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Vasopressor Requirements after Initiation of Venovenous Extracorporeal Membrane Oxygenation in Patients with Severe Respiratory Failure

Abstract Background Patients with severe respiratory failure frequently suffer from concomitant haemodynamic compromise. By correcting respiratory acidosis and permitting reduced mechanical ventilation pressures, venovenous extracorporeal membrane oxygenation (V-V ECMO) may..

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Extracorporeal Carbon Dioxide Removal in Acute Respiratory Distress Syndrome: Physiologic Rationale and Phenotype-Based Perspectives

Abstract Acute respiratory distress syndrome (ARDS) is a major cause of morbidity and mortality despite decades of progress in ventilatory support. Mechanical ventilation, while essential for oxygenation, may exacerbate lung..

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Socioeconomic status and ECMO outcomes in severe ARDS

Abstract Background Socioeconomic inequalities have been associated with adverse outcomes in critically ill COVID-19 patients. Whether these disparities extend to the most severe ARDS patients treated with ECMO, regardless of..

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Comparison between regional citrate anticoagulation and systemic heparin anticoagulation in patients undergoing continuous renal replacement therapy and venoarterial extracorporeal membrane…

Abstract Introduction Regional citrate anticoagulation (RCA) is the recommended first-line strategy for continuous renal replacement therapy (CRRT) circuits. Acute kidney injury is common in patients undergoing venoarterial extracorporeal membrane oxygenation..

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Emergency cesarean section in pregnant women with severe pulmonary hypertension: the potential role of extracorporeal life support

Abstract BACKGROUND: The aim of this study was to present our institutional experience with periprocedural management of emergency cesarean section (CS) operations and maternal and fetal cardiac complications in pregnant..

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The Impact of Hemolytic Processes Due to Extracorporeal Support Therapy on the Serum Concentration of the Neuronal Marker Protein NSE

Abstract Neuron-specific enolase (NSE) is a marker used to assess neurological impairment. Notwithstanding, the release of NSE into the circulation can also originate from erythrocytes and thrombocytes, signifying that even..

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Inguinal Cannulation for Establishing Extracorporeal Circulation in Adult Porcine Model

Abstract Due to the similar size ratios, adult porcine models are suitable for cardiovascular and circulatory physiology studies on extracorporeal circulation. As standard, the connection to the cardiopulmonary bypass (CBP)..

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Multi-modal pediatric critical care datamart for extracorporeal support prediction and decision support

Abstract Objectives To develop a multimodal pediatric critical care datamart supporting predictive modeling and decision support tool development, integrating high-resolution physiologic and clinical data and future clinical deployment. Materials and..

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Multimodal characterization of flow-induced thrombus initiation and growth in extracorporeal membrane oxygenation

Abstract In cases of severe cardiopulmonary failure, extracorporeal membrane oxygenation (ECMO) may be temporarily used as a life-saving support for cardiac and/or lung function. Operating under non-physiological flow conditions, characterized..

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Building an Extracorporeal Membrane Oxygenation Digital Twin Using High-Resolution Patient Data: An artificial intelligence model for virtual reality simulation

Abstract OBJECTIVES Extracorporeal membrane oxygenation (ECMO) is a life-saving therapy for severe cardiopulmonary failure, but structured training remains constrained by costs, logistics, and the absence of validated high-fidelity simulators. This..

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Current rat models of extracorporeal life support following global ischaemia: a scoping review

Abstract Introduction Small animal models are indispensable in cardiovascular research. This scoping review aims to provide an overview of contemporary rat models for extracorporeal life support (ECLS) after global ischaemia...

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Association Between Systemic Anticoagulation and Outcomes in Patients With Acute Respiratory Distress Syndrome Receiving Venovenous Extracorporeal Membrane Oxygenation: Insights From…

Abstract Objective:  To evaluate whether systemic anticoagulation therapy affects the survival of adult patients receiving venovenous extracorporeal membrane oxygenation (VV-ECMO) for acute respiratory distress syndrome (ARDS). Design:  Multicenter retrospective study...

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Predictors of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) failure: analysis of comorbidities and complications – a 10-year experience

Abstract Introduction Regardless of its effectiveness, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support is not a risk-free method. Its use is associated with high complication and mortality rates, especially in patients..

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Outcomes in Adult Patients Requiring Multiple Runs of Extracorporeal Membrane Oxygenation

Abstract Objectives This study describes a single-institution experience of adult patients supported with multiple runs of extracorporeal membrane oxygenation (ECMO) during the same hospitalization. We aim to assess complication and..

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A Homemade Low-Cost Agar-Agar Extracorporeal Membrane Oxygenation Cannulation Model for Extracorporeal Resuscitation Simulation

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) using venoarterial extracorporeal membrane oxygenation (VA ECMO) is a life-saving intervention for selected patients in refractory cardiac arrest. Given the procedure’s technical complexity and time-critical..

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Comparison of Left Ventricular Unloading Strategies During Extracorporeal Membrane Oxygenation

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) offers cardiopulmonary support with the tradeoff of increased left ventricular (LV) afterload and its adverse sequelae. LV decompression strategies include the use of intra-aortic..

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Application of VA-ECMO combined with IABP in a patient with cardiac arrest following fulminant myocarditis

Abstract Background Fulminant myocarditis is a severe cardiac condition characterized by rapid progression and high mortality. In recent years, advancements in medical technology, particularly the application of mechanical circulatory support,..

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Central veno-arterial ECMO via an aortic prosthetic graft as significant alternative to peripheral ECMO cannulation: evaluation of patient outcomes in…

Abstract Background For patients presenting with cardiogenic shock due to acute myocardial ischaemia, veno-arterial extracorporeal membrane oxygenation (ECMO) is often the only potential lifesaving intervention remaining when revascularisation does not..

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Life-Threatening Iatrogenic Pulmonary Hemorrhage Managed with Salvage Anticoagulation-Free Venovenous Extracorporeal Membrane Oxygenation

Abstract SEVERE HEMOPTYSIS REMAINS A significant medical emergency, often requiring a multidisciplinary approach to identify the bleeding source and implement effective treatment. Airway obstruction due to clots secondary to massive..

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Antimicrobial stewardship during extracorporeal membrane oxygenation: challenges and new perspectives

Abstract Background Extracorporeal membrane oxygenation (ECMO) has emerged as a crucial modality in managing severe cardiac and respiratory failure; however, nosocomial infections and complex antimicrobial prescribing challenges may accompany its..

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Diagnostic Pathways for Refractory Hypoxemia in ECMO: A Case-Based Troubleshooting Approach

Abstract Despite significant advancements in critical care practice and extracorporeal technology, refractory hypoxia remains a persistent clinical challenge during extracorporeal membrane oxygenation (ECMO). To demonstrate a systematic, algorithmic pathway for..

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Venoarterial Extracorporeal MembraneOxygenation in Septic Shock and/or Sepsis-induced Cardiomyopathy: A Systematic Review of Fifteen Studies

Abstract Objective(s) To evaluate survival outcomes and identify candidate profiles for venoarterial extracorporeal membrane oxygenation in adult patients with sepsis-induced cardiomyopathy. Design The authors systematically searched PubMed, Embase, and Google..

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Outcomes and prediction of mortality in patientsrequiring prolonged veno-arterial extracorporealmembrane oxygenation support in the PRECISE-ECLS observational study

Abstract Background: Veno-arterial ExtraCorporeal Membrane Oxygenation (V-A ECMO) as a bridge to recovery or long-term assist devices in severe cardiocirculatory failure typically lasts 5-7 days. There is scarce guidance on..

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Argatroban in Patients with Extracorporeal Membrane Oxygenation—A Randomized Controlled Pilot Trial

Abstract INTRODUCTION Unfractionated heparin (UFH) is the most commonly used anticoagulant during extracorporeal membrane oxygenation (ECMO) (1). However, UFH also has several limitations: (i) it requires individualized dosing and close..

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Clinician Variability in a Case about ECMO Candidacy: A Qualitative Analysis

Abstract Introduction Veno-venous extracorporeal membrane oxygenation (VV ECMO) is a life-sustaining technology that supports patients with severe acute respiratory failure. Indications and contraindications to VV ECMO are evolving and professional..

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Safety and Efficacy of Stored Wet-Preprimed Extracorporeal Membrane Oxygenation Circuits: A Scoping Review

Abstract Extracorporeal membrane oxygenation (ECMO) may be a life-saving intervention for patients with respiratory or cardiac failure or cardiac arrest. Storing wet-preprimed ECMO circuits can reduce the time to initiate..

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Detection of Thrombi in Extracorporeal Membrane Oxygenation Circuits Using Low-Frequency Acoustic Measurements

Abstract Extracorporeal membrane oxygenation (ECMO) provides temporary support for patients with severe acute cardiac or respiratory failure. Although thrombotic complications are common during ECMO, the real-time detection and management of..

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Extracorporeal membrane oxygenation escape room simulation teamwork dynamics and effectiveness

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) is a high-risk, low-frequency intervention requiring specialized training and effective teamwork, for which simulation-based training is a valuable tool. Across medical disciplines escape room-style..

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Sex differences in venoarterial extracorporeal membrane oxygenation utilisation and clinical outcomes in Australia

Abstract Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly utilised in critically ill patients with severe cardiac failure and cardiac arrest, yet sex-specific differences in presentation, utilisation, and clinical outcomes..

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Extracorporeal Membrane Oxygenation (ECMO) for Acute Respiratory Distress Syndrome (ARDS) During Pregnancy: A Systematic Review

Abstract Acute respiratory distress syndrome (ARDS) in pregnancy is rare but life-threatening. Extracorporeal membrane oxygenation (ECMO) has been used as rescue therapy in refractory cases, though evidence remains limited. This..

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