Abstract The expanding use of extracorporeal cardiopulmonary resuscitation (ECPR) has introduced new clinical scenarios at the intersection of extracorporeal life support and organ donation. Current donor classification systems do not..
Read MoreAbstract Background: Simulation-based education (SBE) is increasingly used in training students in allied healthcare, yet data on its role in United States (U.S.) perfusion programs are limited. This study surveyed perfusion..
Read MoreAbstract Background Human factors (HF) are integral to patient safety. Simulation-based education (SBE) is widely used to teach HF, yet facilitators conceptualise HF in varied ways. This study explored facilitators’..
Read MoreAbstract Simulation is an excellent educational methodology for healthcare learners to practice skills for medical scenarios that are low in frequency but high in emotional intensity. However, these educational experiences..
Read MoreAbstract Background: Hemodilution during cardiopulmonary bypass (CPB) is a standard perfusion strategy used to reduce blood viscosity and enhance microcirculatory flow. The hemodilution rate, expressed as hemoglobin (Hb) concentration, is..
Read MoreAbstract This study describes the development and preliminary validation of an integrated clinical decision support application (Cardiac Critical Care Advisor Pro, CCA Pro v6.0) that combines viscoelastic coagulation analysis, arterial..
Read MoreAbstract Background Extracorporeal Cardiopulmonary Resuscitation (ECPR) is increasingly considered for prehospital cardiac arrest management; however, its impact on resuscitation performance remains unclear. This study aimed to determine whether integrating an..
Read MoreAbstract Background Children undergoing high-risk cardiac surgery face significant postoperative morbidity and mortality risk, and early recognition of impaired systemic perfusion is critical. Current monitoring modalities, such as lactate, central..
Read MoreAbstract Platelets play a pivotal role in hemostasis, where their activation is tightly regulated by biochemical agonists such as thrombin, collagen, and adenosine diphosphate, all of which signal through calcium-mediated..
Read MoreAbstract Background The clinical impact of early spontaneous breathing during veno-venous extracorporeal membrane oxygenation (VV ECMO) for acute respiratory distress syndrome (ARDS) is unclear, balancing potential benefits (reducing sedation and..
Read MoreAbstract Objective Post-cardiopulmonary bypass (post-CPB) vasoplegia syndrome (VS) is associated with a dysregulated inflammatory response and a higher morbidity and mortality, but the molecular pathways involved have been incompletely identified...
Read MoreCentral and Mixed Venous Oxygen Saturation in Cardiac Surgery: A Systematic Review and Meta-analysis
Abstract Central venous oxygen saturation (ScvO2) and mixed venous oxygen saturation (SvO2) are widely used markers of tissue perfusion. Their role in cardiac surgery remains uncertain. This study conducted a..
Read MoreAbstract Perioperative bleeding remains a major complication in cardiac surgery and is associated with increased morbidity, mortality, and transfusion requirements. While patient blood management strategies and goal-directed hemostatic therapies have..
Read MoreAbstract As ECMO continues to grow beyond the CVOR, a growing number of physicians outside cardiac surgery are being asked to cannulate. This expansion is an important step toward building..
Read MoreAbstract Background The use of extracorporeal membrane oxygenation (ECMO) has expanded for severe respiratory and circulatory failure. Acute kidney injury (AKI) is one of the most frequent complications. Up to..
Read MoreAbstract Background Postoperative recovery in older adults undergoing cardiac surgery is a complex and multidimensional process associated with clinical, psychological, and nutritional factors; however, these factors are often addressed separately..
Read MoreAbstract Background This systematic review and meta-analysis evaluated the clinical efficacy and safety of hemoperfusion in adults receiving extracorporeal membrane oxygenation (ECMO). Methods We systematically searched PubMed, Embase, the Cochrane..
Read MoreAbstract Objective To evaluate the relationship between cardiopulmonary bypass (CPB) duration, change in thoracic fluid content (ΔTFC) measured using electrical cardiometry, and postoperative oxygenation in infants undergoing ventricular septal defect..
Read MoreAbstract Imagine, for a moment, that targeted temperature management (TTM), the standard of care in post cardiac arrest management for more than two decades, was built on a false premise..
Read MoreAbstract Objective Aortic arch surgery remains a complex procedure associated with significant morbidity and mortality. This review aims to provide insights into the current concepts and evidence regarding organ protection..
Read MoreAbstract Objectives Antegrade cerebral perfusion (ACP) is used to protect the brain during aortic arch reconstructions. It is unknown whether cerebral autoregulation remains intact during ACP. This study was designed..
Read MoreAbstract Cardiac arrest is a leading cause of global mortality, with low survival rates despite advances in resuscitation science. Reported survival ranges from 8% to 34% for out-of-hospital and in-hospital..
Read MoreAbstract Mechanical stimulation can remodel the physiological mechanical microenvironment of cardiomyocytes and influence their maturation and injury progression. However, the dynamic process by which cardiomyocytes transition from adaptive maturation to..
Read MoreAbstract Over the past 2 decades, liver transplantation (LT) has undergone a profound transformation in different fields. In particular, once characterized by massive blood product utilization, LT is now characterized..
Read MoreAbstract Background: Establishing the Korean Pediatric and Congenital Heart Surgery Database (KPCHSD) and linking it to the World Database for Pediatric and Congenital Heart Surgery (WDPCHS) is an important step..
Read MoreAbstract Objectives Aortic arch surgery traditionally relies on hypothermic circulatory and cardioplegic arrest, exposing myocardium and visceral organs to ischaemia-reperfusion injury. We developed a total body perfusion (TBP) strategy providing..
Read MoreAbstract Objectives Extracorporeal Membrane Oxygenation (ECMO) is associated with high risks of bleeding and clotting. While traditional anticoagulants like heparin and bivalirudin target the coagulation cascade, prostaglandins including PGE1 and PGI2 may..
Read MoreAbstract Objectives Postoperative atrial fibrillation is common after cardiac surgery. Effective preventative measures are lacking, partly due to an incomplete understanding of its pathogenesis. Inflammation is a major contributor to..
Read MoreAbstract Objectives Inadequate heparin response is frequently observed in neonates and young infants. While low antithrombin level is considered to be the primary cause, the existing literature suggests that it..
Read MoreAbstract Background: Extracorporeal membrane oxygenation (ECMO) candidacy decisions for children with respiratory failure can be variable among pediatric critical care attending physicians, and prior studies showed that baseline functional status..
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