Archives

Perfusfind S.L.

Abstract Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is a complex and invasive intervention used increasingly in the management of severe respiratory failure. Once established, the management of prolonged V-V ECMO..

Perfusfind S.L.

Abstract Importance  Underweight and obesity represent opposite ends of the nutritional risk spectrum that negatively affect children’s health worldwide. Both conditions have been associated with increased mortality in pediatric patients receiving..

Perfusfind S.L.

Abstract Ventricular septal rupture (VSR) is a rare but often fatal complication of acute myocardial infarction (AMI), with a high mortality largely driven by resultant cardiogenic shock. Venoarterial extracorporeal membrane..

Perfusfind S.L.

Abstract Normothermic regional perfusion (NRP) is increasingly implemented to optimize the outcome of transplantation from donors undergoing circulatory determination of death. NRP shortens the duration of warm ischemia, allowing splanchnic..

Perfusfind S.L.

Abstract Disseminated intravascular coagulation (DIC) has long been described as a catastrophic systemic activation of coagulation with suppressed anticoagulant and fibrinolytic pathways, culminating in macro- and microvascular thrombosis, hypoperfusion, and..

Perfusfind S.L.

Abstract Background This study evaluates the outcomes and management considerations associated with using extracorporeal membrane oxygenation (ECMO) in patients with traumatic brain injury (TBI), including those requiring neurosurgical intervention. It..

Perfusfind S.L.

Abstract A clear and systematic terminological framework is essential for exactly describing a patient’s hemodynamic state. After assessing absolute values of hemodynamic variables and considering the specific clinical context, the..

Perfusfind S.L.

Abstract Background Protected cardiac surgery is a proactive strategy that applies temporary mechanical circulatory support to prevent perioperative low cardiac output syndrome in high-risk cardiac surgery. Rather than escalating vasoactive..

Perfusfind S.L.

Abstract Background Bleeding and thrombosis are major complications of micro-axial flow pump (mAFP) support in cardiogenic shock (CS), yet contemporary data on their incidence, temporal trends, and prognostic impact remain..

Perfusfind S.L.

Abstract Anticoagulants are widely used to prevent and treat thrombotic disorders, and continuous advances have refined their efficacy and safety. Beyond their established anticoagulant function, growing evidence indicates that some..

Perfusfind S.L.

Abstract Intractable bleeding during cardiac surgery is a rare but life-threatening complication. We describe a novel management approach in which the patient was supported with venoarterial extracorporeal membrane oxygenation until..

Perfusfind S.L.

Abstract Congenital heart disease (CHD) is the most frequent congenital malformation at birth and is associated with neurodevelopmental impairments. Alterations in cardiovascular physiology can lead to reduced cerebral blood perfusion..

Perfusfind S.L.

Abstract Differential oxygenation may complicate extracorporeal cardiopulmonary resuscitation (ECPR) either due to the initial pathology or subsequent lung injury. The dual circulation phenomenon inherent to peripheral venoarterial extracorporeal membrane oxygenation..

Perfusfind S.L.

Abstract Background Monitoring of unfractionated heparin (UFH) in critically ill patients is challenging due to disease-related alterations of the coagulation system, directly affecting conventional laboratory tests, including activated partial thromboplastin..

Perfusfind S.L.

Abstract Cardiovascular diseases (CVD) remain the leading cause of mortality worldwide, with chronic kidney disease (CKD) constituting a significant risk factor. Despite the crucial role of amino acids as fundamental..

Perfusfind S.L.

Abstract Introduction Veno-venous extracorporeal membrane oxygenation (VV-ECMO) supports oxygenation and carbon dioxide (CO2) clearance in the short- or mid-term, and is traditionally utilized in severe, refractory respiratory failure. There is..

Perfusfind S.L.

Abstract Background Extracorporeal Membrane Oxygenation (ECMO) is a critical rescue therapy complicated by high rates of nosocomial infections (NIs). While Western data abound, evidence from the Middle East remains limited...

Perfusfind S.L.

Abstract Antegrade cerebral perfusion (ACP) and hypothermia are widely used neuroprotective strategies during neonatal aortic arch repairs. Still, over 50% of neonates exhibit new or worsened white matter injury in..

Perfusfind S.L.

Abstract Acute postoperative bioprosthetic valve thrombosis is a rare complication with challenging treatment. We present two consecutive cases of patients with myocardial infarction and papillary muscle rupture requiring urgent surgical..

Perfusfind S.L.

Abstract Introduction Brain infarction (BI) is a severe complication of extracorporeal membrane oxygenation (ECMO) with high morbidity and mortality. We aimed to determine the incidence of BI and identify predictors..

Perfusfind S.L.

Abstract Dear Editor, We read with great interest the article by Tanaka et al. reporting their institutional experience with mechanical circulatory support (MCS) in patients undergoing surgical repair of acute..

Perfusfind S.L.

Abstract BACKGROUND:  Mortality prognostication in adult patients requiring extracorporeal membrane oxygenation (ECMO) is not accurate or established. We hypothesized that composite lactate-based metrics and machine-learning models would improve in-hospital mortality..

Perfusfind S.L.

Abstract Background In order to ensure both surgical safety and reliability, operative management of patients undergoing cardiac surgery requires stringent standards and awareness from cardiac surgeons, anesthesiologists and perfusionists. Among..

Perfusfind S.L.

Abstract Introduction:  In cardiogenic shock (CS), persistent microcirculatory impairment despite improved macrocirculatory parameters is associated with poor outcomes. Therapeutic strategies must therefore address both macro- and micro-circulation. Conventional microcirculatory measures..

Perfusfind S.L.

Abstract Pan and colleagues report the findings of a large, blinded, placebo-controlled single-center randomized clinical trial of sivelestat for the prevention of acute respiratory distress syndrome (ARDS) among patients undergoing..

Perfusfind S.L.

Abstract Rhabdomyolysis is a pathological process that results from the breakdown of skeletal muscle fibers, leading to the release of intracellular contents such as myoglobin, creatine kinase, potassium, and phosphate..

Perfusfind S.L.

Abstract Obesity poses technical challenges during veno-venous extracorporeal membrane oxygenation (VV-ECMO) cannulation because of thick subcutaneous tissue and increased insertion resistance. While patient-related factors are well recognized, the impact of..

Perfusfind S.L.

Abstract Introduction Acute kidney injury (AKI) is a well-known serious complication of cardiopulmonary bypass (CPB) surgery and one of the significant risk factors for mortality, prolonged hospital stay, and additional..

Perfusfind S.L.

Abstract Restoration of coronary blood flow is essential for myocardial salvage in acute myocardial infarction (AMI), yet substantial injury and adverse remodeling often persist after successful reperfusion. Experimental ischemia–reperfusion models..

Perfusfind S.L.

Abstract Although cardiovascular disease (CVD) is the leading cause of mortality globally, it remains insufficiently understood in large parts of the world. The scientific foundations underpinning CVD risk prediction, diagnostics,..