Abstract Normothermic regional perfusion (NRP) is increasingly implemented to optimize the outcome of transplantation from donors undergoing circulatory determination of death. NRP shortens the duration of warm ischemia, allowing splanchnic..
Read MoreAbstract Normothermic regional perfusion (NRP) has emerged as one of the most consequential innovations in modern liver transplantation, particularly in the context of controlled donation after circulatory death (cDCD). Historically,..
Read MoreAbstract Background The increasing prevalence of end-stage heart failure coupled with limited donor organs creates a critical need for novel strategies in heart transplantation. Donation after circulatory death offers a..
Read MoreAbstract Heart transplantation continues to be the definitive treatment option for end-stage heart failure, but its availability remains limited by the imbalance between the supply and demand of suitable donor..
Read MoreAbstract Normothermic regional perfusion (NRP) is an effective method for recovering donation after circulatory death (DCD) organs. However, concerns remain that NRP may allow unintended cerebral perfusion despite clamping of..
Read MoreAbstract Background: The gold standard for treatment of patients with end-stage heart failure remains . Time spent on the active waiting list, notably for patients, contributes to alarmingly high mortality. Donation after..
Read MoreAbstract Normothermic regional perfusion during controlled donation after circulatory death has emerged as a means to increase the number and viability of organs available for transplant. Because normothermic regional perfusion..
Read MoreAbstract Normothermic regional perfusion (NRP) is a strategy of postmortem reperfusion with warm oxygenated blood of a portion of the body applied in donors undergoing circulatory determination of death (DCDDs)...
Read MoreAbstract Background Cardiac allotransplantation is the optimal treatment for end-stage heart failure. However, organ supply remains the principal issue affecting patients. Pediatric patients present unique challenges resulting in long wait-list..
Read MoreAbstract Normothermic regional perfusion (NRP) is a strategy of postmortem reperfusion with warm oxygenated blood of a portion of the body applied in donors undergoing circulatory determination of death (DCDDs)...
Read MoreAbstract Background Donation after circulatory death (DCD) heart transplants have increased in the United States with direct procurement with machine perfusion (DPP) and thoracoabdominal normothermic regional perfusion (TA-NRP) techniques. There..
Read MoreAbstract Background Normothermic regional perfusion (NRP) and direct procurement and perfusion (DPP) allow for transplantation with donation after circulatory death (DCD) hearts. This study aimed to characterize the use of..
Read MoreAbstract Normothermic regional perfusion (NRP) is a surgical technique that can improve the quality and number of organs recovered for donation after the determination of death by circulatory criteria. Despite..
Read MoreAbstract Controlled donation after the circulatory determination of death (cDCDD) has emerged as a strategy to increase the availability of organs for clinical use. Traditionally, organs from cDCDD donors have..
Read MoreAbstract Heart transplantation (HT) is the gold standard treatment of end-stage heart disease. Waitlist mortality remains high due to a shortage of available donor organs. Donation after circulatory death (DCD)..
Read MoreAs the field of organ transplantation continues to evolve, the use of Donation after Circulatory Death (DCD) donors has emerged as a critical method to expand the donor pool. However,..
Read MoreTuscany Normothermic Regional Perfusion Mobile Teams for Controlled Donation After Circulatory Death
Abstract Introduction To facilitate the implementation of controlled donation after circulatory death (cDCD) programs even in hospitals not equipped with a local extracorporeal membrane oxygenation (ECMO) team, some countries have..
Read MoreAbstract Background. Withdrawal of life-sustaining therapy (WLST) performed in the circulatory determination of death (DCD) donors leads to cardiac arrest, challenging the utilization of the myocardium for transplantation. The rapid..
Read MoreAbstract In donation after circulatory death (DCD) organ transplantation, normothermic regional perfusion (NRP) restores oxygenated blood flow following cardiac arrest and reverses warm ischemia. Recently, NRP has also been used..
Read MoreAbstract To the Editor, Rubin argues that the use of normothermic regional perfusion (NRP) during organ recovery in donation after the circulatory determination of death (DCD) amounts to euthanasia..
Read MoreAbstract Regional tissue oxygen saturation (rSO2) monitoring through near-infrared spectroscopy (NIRS) has been reported as a non-invasive strategy to estimate the adequacy of matching between oxygen delivery (DO2) and oxygen..
Read MoreAbstract Thoracoabdominal normothermic (TA-NRP) has recently begun being utilized in the United States for recovery of from some after circulatory death (DCD), but data on lungs recovered in this method is limited to ...
Read MoreAbstract Background Heart transplantation in donation after circulatory death (DCD) relies on warm perfusion using either in situ normothermic regional perfusion (NRP) or ex situ normothermic machine perfusion. In this..
Read MoreAbstract Donation after circulatory death (DCD) programs are expanding in Europe, in the attempt to expand donors pool. Even in controlled DCD donors, however, a protracted warm ischemia time occurring..
Read MoreAbstract Donation after circulatory determination of death has increased the number of organs available but can result in worse recipient outcomes than organs recovered from donors after neurologic death. Normothermic..
Read MoreAbstract Objective This pilot study sought to evaluate the feasibility of our donation after circulatory death (DCD) heart transplantation protocol using cardiopulmonary bypass (CPB) for normothermic regional reperfusion (NRP). Methods..
Read MoreAbstract Controlled donation after circulatory determination of death (DCD), where death is determined after cardiac arrest, has been responsible for the largest quantitative increase in Canadian organ donation and transplants,..
Read More














