Modified cardiac power output as a marker for left ventricular recovery during V-A ECMO
Abstract
Dear Editor,
The timely liberation of cardiogenic shock (CS) patients from veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is crucial to reduce device complications, although the predictor of weaning is still under debate.
Cardiac power output (CPO), calculated as mean arterial pressure(MAP) times cardiac output(CO) /451, is considered a reliable outcome parameter as a surrogate
of hydraulic output heart energy in CS [1], although its role as a prognosticator was challenged [2]. In V-A ECMO, CPO may be unreliable since elevated MAP may be dependent on poor or absent pulsatility biasing its interpretation.
Therefore, we evaluated the predictive value of CPO versus a modified CPO (mCPO) incorporating pulse pressure (PP) instead of MAP.
We extracted data on consecutive patients enrolled in our local database between January 2016 and 2020; the protocol was approved from the Institutional Review
Board of Fondazione IRCCS Policlinico San Matteo (protocol number 60954/2018).