Neurology

The Pupillary Light-Off Reflex in Acute Disorders of Consciousness

Abstract Background In intensive care patients with disorders of consciousness, the pupillary light reflex is a measure of pupillary parasympathetic function. By contrast, the pupillary light-off reflex leads to pupil dilation in response to an abrupt change from light to darkness (“light-off”) and reflects combined parasympathetic and sympathetic pupillary function. To our knowledge, this reflex […]

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