cardiac dysfunction archivos - Perfusfind Intensive Care

Sepsis-induced cardiac dysfunction: mitochondria and energy metabolism

Summary of Sepsis-induced cardiac dysfunction: mitochondria and energy metabolism (Yu et al.) Abstract Summary: Yu et al. systematically reviewed the pathophysiological mechanisms underlying sepsis-induced myocardial dysfunction (SIMD), emphasizing mitochondrial dysfunction and disruptions in myocardial energy metabolism. The review highlights critical aspects, including alterations in myocardial substrates, mitochondrial damage, oxidative stress, calcium imbalance, mitochondrial DNA (mtDNA) […]

cardiac dysfunction, energy metabolism, sepsis

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Pharmacological Insights in Critical Care, Sepsis

Ivabradine in Septic Shock: A Narrative Review

Abstract In patients with septic shock, compensatory tachycardia initially serves to maintain adequate cardiac output and tissue oxygenation but may persist despite appropriate fluid and vasopressor resuscitation. This sustained elevation in heart rate and altered heart rate variability, indicative of autonomic dysfunction, is a well-established independent predictor of adverse outcomes in critical illness. Elevated heart

cardiac dysfunction, Ivabradine, multiple organ disfunction syndrome, septic cardiomyopathy, septic shock, β-blockers

Ivabradine in Septic Shock: A Narrative Review Read Post »