Archives

Perfusfind S.L.

Abstract Background: A 17-year-old male patient diagnosed with a single ventricle, in a failed Fontan stage, was evaluated prior to heart transplantation. The patient had a panel-reactive antibody (PRA) for..

Perfusfind S.L.

Abstract Background Intraoperative sodium changes and new postoperative white matter injury are prevalent in neonates with congenital heart disease (CHD) who undergo cardiopulmonary bypass surgery. Rapid sodium correction in hyponatremia..

Perfusfind S.L.

Abstract Introduction: The absence of a congenital heart surgery national registry limits understanding of access, surgical volume, and mortality. This study analyzes the Brazilian administrative data to assess procedural distribution, outcomes,..

Perfusfind S.L.

Abstract Hereditary spherocytosis (HS) is a rare inherited haemolytic anaemia. This case report outlines a neonatal patient with presumed HS requiring cardiopulmonary bypass (CPB) and the whole blood exchange transfusion..

Perfusfind S.L.

Abstract Introduction Post-CPB bleeding remains a critical challenge in neonatal cardiac surgery, and early detection of coagulopathy to guide transfusion decisions may offer significant benefits. We hypothesized that routine use..

Perfusfind S.L.

Abstract Excessive right heart load imposes an acute or chronic injury on the right ventricle (RV), predisposing critically ill neonates and cardiac surgical patients to RV failure, low cardiac output..

Perfusfind S.L.

Abstract Antithrombin (AT), a glycoprotein, plays a key role in anticoagulation by inhibiting coagulation proteases. It is also the primary mediator of heparin's anticoagulant effect, with heparin binding amplifying AT..

Perfusfind S.L.

Abstract Background Refractory cardiac arrest remains a major challenge in children, with poor survival despite advances in cardiopulmonary resuscitation (CPR). Extracorporeal cardiopulmonary resuscitation (ECPR), defined as rapid deployment of extracorporeal..

Perfusfind S.L.

Abstract Background Pediatric cardiac surgery with cardiopulmonary bypass (CPB) is associated with systemic inflammation. This trial aimed to determine whether continuous high-exchange ultrafiltration during CPB has a clinical immunomodulatory effect...

Perfusfind S.L.

Abstract A six-month-old, 3.3-kg, intact male American shorthair cat with a ventricular septal defect (VSD) underwent open-heart surgery using total cardiopulmonary bypass. Repair of the VSD was performed via a..

Perfusfind S.L.

Abstract Objectives This study aimed to investigate whether prebypass endogenous melatonin concentrations are associated with perioperative oxidative DNA injury, indexed by urinary 8-hydroxy-2′-deoxyguanosine (8-OHdG), and to explore their relationship with..

Perfusfind S.L.

Abstract Background Drawing on more than 30 years of valuable expertise in in-vitro, in-vivo, and clinical trials, we report the key findings of our institutional research on pulsatile cardiopulmonary bypass..

Perfusfind S.L.

Abstract Background Acute kidney injury (AKI) is a common complication after pediatric cardiac surgery using cardiopulmonary bypass (CPB). This study evaluated renal regional oxygen saturation (R-rSO₂), measured via near-infrared spectroscopy..

Perfusfind S.L.

Abstract Objectives This quality improvement project aimed to enhance operating room efficiency in a newly established paediatric cardiac operating room by focusing on key performance indicators (KPI), including (1) first..

Perfusfind S.L.

Abstract Design Apixaban is a direct oral anticoagulant that inhibits factor Xa. Our objective was to examine the effect of apixaban on perioperative transfusion requirements in pediatric patients undergoing cardiac..

Perfusfind S.L.

Abstract Background/Objectives: In the present study, we hypothesized that cardiac surgery in pediatric patients with congenital heart disease (CHD) leads to profound endothelial glycocalyx degradation, measured as the increase in..

Perfusfind S.L.

Abstract Racial and ethnic disparities and language barriers coexist with inequities in a child’s educational, environmental, and economic opportunity. We evaluated the association between surgical outcomes and a composite child..

Perfusfind S.L.

Abstract The number of potential pediatric heart transplant recipients continues to exceed the number of donors, and consequently the waitlist mortality remains significant. Despite this, around 40% of all donated..

Perfusfind S.L.

Abstract Background Donor discard rates for pediatric heart transplant (HT) remain high (≈40%), often driven by concerns about elevated donor troponin levels. This study evaluated the association between peak donor..

Perfusfind S.L.

Abstract Background:  Acute kidney injury (AKI) is a frequent complication of congenital heart surgery with cardiopulmonary bypass (CPB) in pediatric patients, contributing to significant morbidity and mortality. Aim:  To determine..

Perfusfind S.L.

Abstract Introduction Heparin induced thrombocytopenia (HIT) with in paediatric population is rare and subsequent anticoagulation management is challenging. Bivalirudin is a viable alternative to heparin for anticoagulating paediatric patients with..

Perfusfind S.L.

Abstract Objective To investigate the association of Tau protein levels with postoperative evidence of neural injury following cardiopulmonary bypass (CPB) in pediatric cardiac surgery patients. Methods One hundred forty-four consecutive..

Perfusfind S.L.

Abstract Hyperoxia in pediatric cardiopulmonary bypass patients is associated with adverse effects, including reoxygenation injury, increased mortality, heightened inflammatory response, and cerebral injury. Although prior research has demonstrated a correlation..

Perfusfind S.L.

Abstract Background:Infants with CHD who undergo cardiopulmonary bypass surgery are at risk of impaired growth and neurodevelopment. However, few studies have thoroughly investigated the risk factors for growth and neurodevelopmental..

Perfusfind S.L.

Abstract Background Children with congenital heart disease are at risk for poor neurodevelopment. The gut microbiome may influence neurodevelopmental outcomes through the gut-brain axis. This study investigated the association of..

Perfusfind S.L.

Abstract Background Acute Kidney Injury (AKI) is a frequent post-operative complication following cardiac surgery in the clinical setting. Iron metabolism disorders are a key cause of kidney injury during the..

Perfusfind S.L.

Abstract Objectives Neonates with complex congenital heart disease (CHD), in particular newborns with hypoplastic left heart syndrome (HLHS) or transposition of the great arteries (TGA), may show brain pathologies and..

Perfusfind S.L.

LVAD Implantation in Pediatric Population inflow from LV and outflow to Ascending Aorta.   LVAD Implantation in the Pediatric Population   By Sam Zeraatiannejaddavani, MD   ⸻   A —..

Perfusfind S.L.

Abstract Background Children with heart disease and cardiopulmonary failure may be supported with extracorporeal membrane oxygenation (ECMO) for stabilization before cardiac surgery. This study describes their epidemiology and outcomes. Methods..

Perfusfind S.L.

Abstract Objectives:  To derive and externally validate supervised machine learning (ML) models predictive of cardiac surgery-associated acute kidney injury (CS-AKI). Design:  Retrospective cohort analysis. Setting:  Multicenter (4), cardiac surgical centers..