Archives

thumbnail
0 comment

Using an intermittent flow (“clamp and flash”) method to assess the readiness to wean from VA ECMO in adult and…

Abstract Background: The use of VA extracorporeal membrane oxygenation (ECMO) for cardiac recovery is widely adopted, with extensive publications on assessing readiness to wean from VA ECMO. Techniques to reduce..

Read More
thumbnail
0 comment

Venovenous Extracorporeal Membrane Oxygenation Outcomes in Cirrhosis: An Extracorporeal Life Support Organization Registry Study

Abstract Cirrhosis was previously listed in Extracorporeal Life Support Organization (ELSO) guidelines as an absolute contraindication for venovenous extracorporeal membrane oxygenation (VV ECMO) and has since been removed. Minimal data..

Read More
thumbnail
0 comment

Evaluation of Cerebral Blood Pressure During Normothermic Regional Perfusion

Abstract Normothermic regional perfusion (NRP) is an effective method for recovering donation after circulatory death (DCD) organs. However, concerns remain that NRP may allow unintended cerebral perfusion despite clamping of..

Read More
thumbnail
0 comment

Hemodynamics in femoro-femoral venovenous extracorporeal membrane oxygenation using large eddy simulations

Abstract Venovenous extracorporeal membrane oxygenation (ECMO) is used for support in refractory severe respiratory failure. Venous drainage and return are accomplished through cannulation of patient’s major veins, typically on the..

Read More
thumbnail
0 comment

Understanding the Outcomes of Extracorporeal Membrane Oxygen Support in Patients With Sickle Cell Trait

Abstract The impact of common hemoglobinopathies, such as sickle cell trait (SCT), on outcomes in adults requiring extracorporeal membrane oxygenation (ECMO) remains understudied. Extracorporeal Life Support Organization registry data was..

Read More
thumbnail
0 comment

Buttock ischemia in adults with femoral venoarterial-extracorporeal membranoxygenation – A single center experience

Abstract Introduction Femoral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is used as an ultima ratio to maintain circulation in patients with refractory cardiorespiratory failure, but is also associated with vascular and..

Read More
thumbnail
0 comment

A silicon membrane microfluidic oxygenator for use as an artificial placenta with minimal anticoagulation

Abstract Extreme prematurity carries a high burden of morbidity and mortality. The artificial placenta is an emerging therapy that has the potential to improve outcomes in these patients. However, current..

Read More
thumbnail
0 comment

Complications of microaxial flow pump and VA-ECMO in infarct-related cardiogenic shock: Insights from the Netherlands heart registration

Abstract Background Active mechanical circulatory support (MCS) is associated with high complication rates. Reducing device-related complications may improve outcomes in patients with infarct-related cardiogenic shock (AMI-CS). This study aims to..

Read More
thumbnail
0 comment

Baseline characteristics and in-hospital mortality predictors in female patients on venovenous extracorporeal membrane oxygenation: Impact of pregnancy

Abstract Background Venovenous extracorporeal membrane oxygenation (VV-ECMO) is often used for lung rest in critically ill patients, including pregnant patients. Objectives We aimed to determine how pregnant and non-pregnant patients..

Read More
thumbnail
0 comment

Predicting Successful Weaning from Veno-Arterial ECMO Using Machine Learning

Abstract Extracorporeal Membrane Oxygenation (ECMO) is a life-saving cardiopulmonary support for patients with acute heart failure. However, the process of weaning from veno-arterial (V-A) ECMO remains complex and risky. We..

Read More
thumbnail
0 comment

Simulation-Based Education for Extracorporeal Membrane Oxygenation and Strategies for Implementation

Abstract Simulation-based education (SBE) in health care is expanding in both scope and relevance. As on-the-job training is challenging in extracorporeal membrane oxygenation (ECMO), SBE features strongly in its curricula,..

Read More
thumbnail
0 comment

ELSO 2025 Narrative Guideline on the Use of ECMO for Accidental Hypothermia

Background Accidental hypothermia (AH) can be caused by exposure to cold weather conditions, immersion in water, avalanche burial in snow, or indoors, mostly affecting elderly patients with multiple comorbidities., There are..

Read More
thumbnail
0 comment

Clinical outcomes of levosimendan administration in veno-arterial extracorporeal membrane oxygenation: a meta-analysis

Abstract Objectives To evaluate the effectiveness of levosimendan in promoting weaning from veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in patients with refractory cardiogenic shock through a meta-analysis of clinical trials. Design Systematic review..

Read More
thumbnail
0 comment

Selective Cytopheretic Device Therapy in the Context of Extracorporeal Membrane Oxygenation

Abstract This review examines the clinical data and basic science research to evaluate the potential of the Selective Cytopheretic Device (SCD) in mitigating Extracorporeal Membrane Oxygenation (ECMO)-associated inflammation. In brief,..

Read More
thumbnail
0 comment

Radiomics-enhanced modelling approach for predicting the need for ECMO in ARDS patients: a retrospective cohort study

Abstract Decisions regarding veno-venous extracorporeal membrane oxygenation (vv-ECMO) in patients with acute respiratory distress syndrome (ARDS) are often based solely on clinical and physiological parameters, which may insufficiently reflect severity..

Read More
thumbnail
0 comment

Prolonged Mechanical Ventilation Before Venovenous Extracorporeal Membrane Oxygenation and In-Hospital Mortality in Patients With Acute Respiratory Distress Syndrome

Abstract Objectives:  To evaluate the relationship between the duration of pre-extracorporeal membrane oxygenation (ECMO) mechanical ventilation and mortality in acute respiratory distress syndrome (ARDS) patients undergoing venovenous ECMO. Design:  Retrospective..

Read More
thumbnail
0 comment

Residual blood management after ECMO weaning: Reinfuse, salvage, or discard?

Abstract Extracorporeal membrane oxygenation (ECMO) supports patients with severe refractory cardiac or respiratory failure but managing residual circuit blood after weaning lacks consensus. After decannulation, the oxygenator and circuit retain..

Read More
thumbnail
0 comment

Infection risks in patients treated by continuous renal replacement therapy and extracorporeal membrane oxygenation

Abstract Purpose of review  This review addresses the growing concern over nosocomial infections in patients undergoing extracorporeal membrane oxygenation (ECMO) and/or continuous renal replacement therapy (CRRT). As the use of..

Read More
thumbnail
0 comment

The Association of Physical Therapy Timing and Frequency With Functional Outcomes in Patients Supported With Extracorporeal Membrane Oxygenation: A Single-Center…

Abstract IMPORTANCE:  Physical therapy (PT) interventions for patients supported with extracorporeal membrane oxygenation (ECMO) is thought to help preserve independence, but the impact of PT frequency on ECMO recovery is..

Read More
thumbnail
0 comment

Rapid Cycle Deliberate Practice Extracorporeal Membrane Oxygenation Simulation in the Cardiac Catheterization Laboratory

Abstract Delays in mechanical circulatory support initiation, in particular extracorporeal membrane oxygenation (ECMO), can exceed an hour while awaiting a specialized shock team. Delays can negatively impact patient outcomes. To address..

Read More
thumbnail
0 comment

Extracorporeal Membrane Oxygenation Cannulation by Intensivists: A Systematic Review and Meta-Analysis

Abstract Purpose To summarize the currently available evidence regarding the effectiveness and safety of extracorporeal membrane oxygenation (ECMO) cannulation performed by intensivists. Methods We conducted a systematic search of MEDLINE,..

Read More
thumbnail
0 comment

Effect of Cytokine Hemoadsorption Therapy in Rats During Venovenous Extracorporeal Membrane Oxygenation

Abstract Cytokine hemoadsorption therapy has been proposed to reduce inflammation in patients with hyperinflammation. However, the clinical benefit of cytokine hemoadsorption therapy during venovenous extracorporeal membrane oxygenation (VV ECMO) is..

Read More
thumbnail
0 comment

Effects of Inadvertent Left Atrial Return During Venovenous Extracorporeal Membrane Oxygenation: The Veno-Left Atrial Case Series

Abstract Venovenous extracorporeal membrane oxygenation (V-V ECMO) is a life-saving organ support for patients with severe respiratory failure. One of the possible complications involves cannula positioning, but the literature has..

Read More
thumbnail
0 comment

Conventional versus pump-controlled retrograde trial off (PCRTO) weaning in V-A ECMO: exploring feasibility, physiological insights and benefits

Abstract Weaning from veno-arterial extracorporeal membrane oxygenation (V-A ECMO) and determining the optimal timing for liberation from mechanical circulatory support (MCS) remain critical yet complex. Although multiple weaning protocols exist,..

Read More
thumbnail
0 comment

Management of Amniotic Fluid Embolism (AFE) using anticoagulation-free ECMO

Abstract Amniotic fluid embolism (AFE) is a critical obstetric complication characterized by the entry of amniotic fluid and its components into maternal circulation during parturition, leading to acute cardiopulmonary failure,..

Read More
thumbnail
0 comment

ECMO in Pregnancy: Analysis of Indications, Management and Outcomes

Abstract Extracorporeal membrane oxygenation (ECMO) has become a critical rescue therapy for pregnant and peripartum patients experiencing life-threatening cardiac or respiratory failure that is refractory to standard treatments. Pregnancy induces..

Read More
thumbnail
0 comment

Optimizing Extracorporeal Membrane Oxygenation Gas Exchange: Key Insights for Clinical Management

Abstract This review examines the role of extracorporeal membrane oxygenation (ECMO) in the management of severe acute respiratory distress syndrome (ARDS), emphasizing its contribution to lung-protective ventilation through optimizing oxygenation..

Read More
thumbnail
0 comment

Effectiveness and safety of bivalirudin anticoagulation therapy in adult patients receiving extracorporeal membrane oxygenation: A systematic review and meta-analysis

Abstract Background:  Compared to heparin, there is limited evidence of the benefits of bivalirudin in the patients with extracorporeal membrane oxygenation (ECMO). Methods:  We searched for studies comparing bivalirudin anticoagulation..

Read More
thumbnail
0 comment

Von Willebrand factor in Ecmo: a dynamic modulator of hemorrhage and thrombosis

Abstract Von Willebrand factor (vWF) orchestrates hemostasis through platelet activation, factor VIII stabilization, and inflammatory modulation, with emerging evidence highlighting its shear-dependent conformational dynamics as a critical regulator of thrombus..

Read More
thumbnail
0 comment

Cell-free hemoglobin is associated with microcirculatory perfusion disturbances and acute kidney injury in rats on extracorporeal membrane oxygenation

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life-saving treatment, but carries a high risk of complications such as acute kidney injury (AKI). A contributor to AKI is hemolysis, which..

Read More