Abstract Extracorporeal life support has become a widely integrated tool in treating refractor cardiopulmonary failure. Under normal physiologic conditions, arterial blood flow is inherently pulsatile, and cyclic shear stress plays..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) has become an increasingly vital intervention for patients with severe cardiac and respiratory failure, significantly improving short-term survival rates. However, there is growing recognition of..
Read MoreAbstract Background Despite advancements in management strategies, patients with refractory cardiogenic shock (CS) have high mortality. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly utilized as temporary mechanical support in these..
Read MoreAbstract Extracorporeal life support (ECLS) is increasingly used to rescue patients with refractory respiratory failure, cardiogenic shock and/or cardiac arrest. Acute brain injury during ECLS is common and associated with..
Read MoreAbstract Background Post-cardiotomy cardiogenic shock (PCCS) remains one of the most lethal complications of cardiac surgery, with high in-hospital mortality despite major improvements in operative techniques, and intensive care management...
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) supports patients with end-stage heart and lung disease awaiting transplantation. In pulmonary hypertension, veno-arterial ECMO (VA-ECMO) is common but linked to vascular complications and limited..
Read MoreAbstract Background In adult patients receiving veno-venous Extracorporeal Membrane Oxygenation (VV ECMO), cardiovascular performance plays a critical role in determining oxygen delivery, organ perfusion and safe titration of extracorporeal support...
Read MoreAbstract Background Extracorporeal membrane oxygenation (ECMO) is an established life support technique for refractory acute cardiorespiratory failure in children and adult patients. However, ECMO support is provided only by specialized..
Read MoreAbstract Background Traumatic major limb amputations require urgent intervention to prevent irreversible tissue necrosis and life-threatening systemic complications due to warm ischemia. We aim to demonstrate the efficacy of extracorporeal..
Read MoreAbstract Background Refractory end-stage lung failure may benefit from extracorporeal life support (ECLS) as a bridge to lung transplantation. Venovenous (VV) extracorporeal membrane oxygenation (ECMO) is indicated in patients who..
Read MoreAbstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a commonly used in refractory cardiogenic shock (CS) but may exacerbate left ventricular (LV) loading conditions and impair cardiac energetics. Adjunctive LV..
Read MoreAbstract Background Extracorporeal circulation (ECC) is an essential operation in many cardiac surgeries, but contact between blood and connecting tubes can activate inflammatory factors and adversely affect complement. Previous studies..
Read MoreAbstract In extracorporeal therapies such as cardiopulmonary bypass (CPB) or extracorporeal membrane oxygenation (ECMO), the transport of blood through artificial circulation frequently results in the rupture of erythrocytes, releasing hemoglobin..
Read MoreAbstract Objectives To determine whether preoperative platelet (PLT) count independently predicts in-hospital mortality in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO). Design Secondary analysis of a prospectively maintained institutional registry...
Read MoreAbstract Objective This study aimed to investigate the association of continuous renal replacement therapy (CRRT) use with the prognosis of patients undergoing extracorporeal membrane oxygenation (ECMO) and to explore its..
Read MoreAbstract Background Acute kidney injury (AKI) is frequent in patients supported with venoarterial extracorporeal membrane oxygenation (VA-ECMO), largely due to the severity of cardiogenic shock and multiorgan failure. Renal replacement..
Read MoreAbstract Background Patients supported with extracorporeal membrane oxygenation (ECMO) are susceptible to healthcare-associated infections (HAIs), which may worsen outcomes. However, epidemiological data from Latin American centres remain scarce. Methods We..
Read MoreAbstract Although extracorporeal membrane oxygenation (ECMO) has emerged as a pivotal temporary extracorporeal life support in critically ill patients, it is associated with a high risk of mortality. Establishing a..
Read MoreAbstract Acute kidney injury (AKI) and fluid accumulation (FA) are common during extracorporeal membrane oxygenation (ECMO) support and are associated with increased morbidity and mortality. Despite their clinical importance, contemporary..
Read MoreAbstract Introduction Bleeding and clotting phenotypes are common in patients supported with Extracorporeal Membrane Oxygenation (ECMO) and are associated with increased mortality. However, tools to distinguish bleeding from clotting phenotypes..
Read MoreAbstract Factor XIII (FXIII) contributes to clot stability and reduces clot susceptibility to lysis through fibrin cross-linking. Standard coagulation tests like prothrombin time and activated partial thromboplastin time do not..
Read MoreAbstract Decompensated differential carbon dioxide (CO2) removal can occur during spontaneous breathing on peripheral venoarterial extracorporeal membrane oxygenation (V-A ECMO) when a low right radial arterial partial pressure of carbon..
Read MoreAbstract Introduction Early detection of acute brain injury (ABI) in patients on venoarterial extracorporeal membrane oxygenation (VA ECMO) is challenging. We aimed to investigate if heart rate variability (HRV) in..
Read MoreAbstract Despite the advances in technology, new patient populations, new medications, and multiple monitoring algorithms for anticoagulation, bleeding, and thrombosis complications remain high among those receiving extracorporeal life support (ECLS)..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) has increasingly been used in patients with refractory severe cardiorespiratory failure in recent years. The use of ECMO necessitates anticoagulation as blood passes through an..
Read MoreAbstract Background and Aims Extracorporeal life support (ECLS) is a critical intervention in the management of severe cardiac and respiratory failure. Among the commonly used cannulation techniques, percutaneous cannulation (PC)..
Read MoreAbstract Extracorporeal life support provides temporary cardiorespiratory support for patients with severe, potentially reversible cardiac and/or respiratory failure refractory to conventional measures. Its application has broadened across a wide spectrum..
Read MoreAbstract Introduction Extracorporeal membrane oxygenation (ECMO) is a type of mechanical circulatory support that is increasingly utilised for severe cardiorespiratory failure in the intensive care unit (ICU) setting. ECMO is..
Read MoreAbstract Open thoracoabdominal aortic aneurysm repair (TAAAR) is associated with mortality rates of between 8% and 25%. One of the characteristics of TAAAR is massive bleeding that requires multiple units..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) can trigger a systemic inflammatory response syndrome (SIRS) with activation of inflammatory, endothelial, and coagulation system pathways. We assessed in a randomized trial whether a)..
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