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Extracorporeal Carbon Dioxide Removal Combined With Inhaled Nitric Oxide for Hypercapnic Acute Respiratory Distress Syndrome With Active Airway Hemorrhage: A…

Abstract Low-flow extracorporeal carbon dioxide removal (ECCO2R) may be useful when severe hypercapnia limits ultra-protective ventilation but full venovenous extracorporeal membrane oxygenation (VV-ECMO) is not pursued. We describe a 68..

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Antimicrobial use in adult patients receiving extracorporeal membrane oxygenation in a center without routine prophylaxis

Abstract Antimicrobial use in patients receiving extracorporeal membrane oxygenation (ECMO) is poorly described. In this study, evaluating antimicrobial use at a single center without ECMO-specific antimicrobial prophylaxis protocols, antimicrobials were..

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Extracorporeal membrane oxygenation in congenital cardiac surgery: a 10-year single-centre experience

Abstract Introduction:Extracorporeal Membrane Oxygenation (ECMO) has evolved as an effective mechanical support for cardiorespiratory failure in patients undergoing congenital cardiac surgery, and the threshold of using it has substantially reduced...

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Challenging the Obesity Paradox: A Multicenter Study of Body Mass Index and Mortality in Venovenous Extracorporeal Membrane Oxygenation

Abstract Obesity is common among critically ill adults, but its association with outcomes during venovenous extracorporeal membrane oxygenation (VV ECMO) remains controversial. We evaluated associations of body mass index (BMI)..

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Development and validation of a novel nursing activities for extracorporeal membrane oxygenation scale in the Netherlands: A nationwide multicentre study

Abstract Objectives To develop and validate a scale to measure nursing activities in patients receiving extracorporeal membrane oxygenation (ECMO) and to examine its underlying factor structure. Methods A multicentre cross-sectional..

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Palliative Extracorporeal Membrane Oxygenation Decannulation: An Ethical, Evidence-Based Approach

Abstract Background Extracorporeal membrane oxygenation, although lifesaving, is invasive. Complications affecting all body systems mandate reevaluation of goals of care. When extracorporeal membrane oxygenation is nonbeneficial, planning for de-escalation/decannulation to..

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Patient-reported outcome and experience measures in post-ECMO follow-up: a scoping review

Abstract Objectives To map the use of patient-reported outcome measures (PROMs) and patient-reported experience measures (PREMs) in adult follow-up after extracorporeal membrane oxygenation (ECMO), and to identify measurement gaps relevant..

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Extracorporeal Membrane Oxygenation Cannulation and Early Management in the Emergency Resuscitation Room Versus Intensive Care Unit: Single-Center Experience

Abstract In this single-center retrospective cohort study, we compared extracorporeal membrane oxygenation (ECMO) cannulation and early management performed in the emergency resuscitation room (ERR) versus the intensive care unit (ICU)...

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Cerebro‑Cardiovascular Coupling During Extracorporeal Membrane Oxygenation Using Cerebral Oxygenation, Doppler Flow, and Echocardiography

Abstract Cerebral injury remains a major contributor to morbidity and mortality in VA‑ECMO patients. Disruption of cerebral autoregulation during extracorporeal support may predispose to neurological damage. This prospective study evaluated..

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Electrical Impedance Tomography Reveals Venoarterial Extracorporeal Membrane Oxygenation Flow-Induced Ventilation-Perfusion Mismatch

Abstract An obese female patient with ischemic cardiomyopathy was placed on venoarterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock after in-hospital cardiac arrest. Despite biventricular recovery by day 3, VA-ECMO..

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Interfacial Pathway in EAS-Modified PMP Membranes Synergistically Enhances CO2/O2 Selectivity for ECMO

Abstract Efficient and selective gas transport across soft and nonporous interfaces remains a pivotal challenge for biomimetic membrane design, particularly in extracorporeal membrane oxygenation (ECMO) systems. Here, we report a..

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Characterization of Ventilator-Associated Pneumonia in Patients Receiving Extracorporeal Membrane Oxygenation Support

Abstract In this retrospective cohort study at a quaternary referral hospital, 829 adult patients supported by extracorporeal membrane oxygenation (ECMO) between January 1, 2014, and October 31, 2024, were screened..

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Resuscitative Transesophageal Echocardiography Simulation Based Education for Extracorporeal Cardiopulmonary Resuscitation Cannulation Guidance

Abstract Extracorporeal membrane oxygenation (ECMO) cannulation during refractory cardiac arrest has become a key therapeutic option in contemporary critical care medicine. When initiated in a timely manner, extracorporeal cardiopulmonary resuscitation..

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Mechanical circulatory support strategy in post–myocardial infarction ventricular septal defect repair

Abstract Post–myocardial infarction (PMI) ventricular septal defect (VSD) repair is associated with high mortality., The pathophysiology varies based on the size of the infarction and the VSD, which results in..

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A Novel Extracorporeal Membrane Oxygenation System With Enhanced Hemocompatibility and Long-Term Stability

Abstract To optimize and evaluate the hydrodynamic performance and gas exchange efficiency of a newly developed centrifugal blood pump and membrane oxygenator for extracorporeal membrane oxygenation (ECMO) support, blood pump..

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Re-evaluation of oxygenation and oxygen exposure in patients with ARDS and veno-venous extracorporeal membrane oxygenation

Abstract Optimal oxygen target levels for critically ill patients have been discussed for decades and very low but also high PaO2-levels were both associated with higher mortality [, ]. In..

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Liquid Lung Rest During Extracorporeal Life Support in a Neonatal Porcine Model of Acute Lung Injury

Abstract In patients with severe lung injury, extracorporeal life support (ECLS) enables lung rest, but the optimal strategy is unknown. This study compared liquid lung rest (LLR) versus standard gas rest ventilation..

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What is missing from fluid balance calculations during ECMO? Water loss from the membrane lung

Abstract Fluid administration and fluid balance are both important clinical considerations in the management of patients receiving extracorporeal membrane oxygenation (ECMO). Insufficient intravascular volume may limit the output of preload-dependent..

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Prosthetic valve thrombosis on venoarterial extracorporeal membrane oxygenation support: Risk factors and outcomes

Abstract Introduction In patients with prior valve replacement requiring venoarterial extracorporeal membrane oxygenation (VA ECMO), there is a risk of prosthetic valve thrombosis (PVT) due to intracardiac stasis. We describe..

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Bilateral radial arterial pressure concordance as a real-time bedside marker of native cardiac recovery during peripheral VA-ECMO weaning

Abstract Patients supported with peripheral femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO) frequently face the challenge of determining the optimal timing for weaning trials, as no universally standardized bedside method is..

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Rehabilitation Intensity and Discharge Outcomes in Venovenous Extracorporeal Membrane Oxygenation Used as a Bridge to Recovery

Abstract Early rehabilitation during venovenous extracorporeal membrane oxygenation used as a bridge to recovery (VV ECMO–BTR) may help preserve functional capacity. We retrospectively analyzed 153 adults supported with VV ECMO–BTR..

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Lactate clearance and volume status at cannulation are associated with survival in trauma VV ECMO patients

Abstract Background Veno-venous extracorporeal membrane oxygenation (VV ECMO) is an advanced therapy for patients with respiratory failure refractory to conventional management. Volume overload and elevated lactate levels have been associated..

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Impact of intra-aortic balloon pump support on cerebral blood flow velocity during venoarterial ECMO

Abstract Introduction Venoarterial extracorporeal membrane oxygenation (V-A ECMO) is frequently combined with intra-aortic balloon pump (IABP) support in patients with refractory cardiogenic shock. Although IABP may reduce V-A ECMO–related afterload,..

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Clinical and Functional Outcomes Following Repeat VA-ECMO in Adults: A Propensity Score–Matched Comparative Study

Abstract Background/Objectives: Evidence on outcomes after repeat VA-ECMO in adults remains limited. This study aimed to compare survival and post-discharge functional outcomes between adults requiring a second VA-ECMO run and..

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ECMO artificial intelligence: matching the model to the clinical question

Abstract One theme worth emphasizing is that “ECMO prediction” is not a single task. Some models are intended to inform decisions before cannulation, whereas others incorporate variables such as ECMO..

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Veno-arterial-venous Extracorporeal Membrane Oxygenation with a Hemoconcentrator to Manage Transfusion Associated Hyperkalemic Arrest

Abstract Liver transplantation (LT) is an established therapy for patients with end-stage liver disease. Advances in surgical technique, anesthetic management, and standardization of perioperative care have significantly improved outcomes, making..

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Comparative Performance of Oxygenators for Extracorporeal Membrane Oxygenation in Adults: A Retrospective Analysis

Abstract Extracorporeal membrane oxygenation (ECMO) is a vital therapy for patients with severe cardiac and pulmonary failure. Despite technological advances, oxygenator dysfunction remains common, yet comparative clinical data across devices..

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Circuit-Directed Nitric Oxide in Anticoagulation-Contraindicated Adult Extracorporeal Membrane Oxygenation: A Single-Center Case Series

Abstract Oxygenator thrombosis is a major complication during extracorporeal membrane oxygenation (ECMO), but systemic anticoagulation may be contraindicated by active hemorrhage, recent surgery, intracranial injury, or severe coagulopathy. Circuit-directed nitric..

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Levosimendan During VA-ECMO for Cardiogenic Shock: An Updated Systematic Review and Meta-analysis Including the LEVOECMO Trial

Abstract Background Levosimendan is often given during venoarterial extracorporeal membrane oxygenation (VA-ECMO) support with the intention of facilitating weaning. The available evidence, however, has been derived largely from nonrandomized studies..

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Protocol and Statistical Analysis Plan for the ECMO-Free Trial

Abstract Background Decannulation from venovenous extracorporeal membrane oxygenation (ECMO) at the earliest safe opportunity would be expected to improve patient outcomes. Currently, the manner in which clinicians liberate patients from..

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