Archives

Perfusfind S.L.

Abstract Background Severe glucose-6-phosphate dehydrogenase (G6PD) deficiency presents unique challenges during cardiopulmonary bypass (CPB) because of increased susceptibility to oxidative injury and haemolysis. Published guidance regarding optimal perfusion management remains..

Perfusfind S.L.

Abstract Cardiopulmonary bypass (CPB) during heart surgery provokes an inflammatory response that can cause post-operative organ injury, yet how CPB shapes key neutrophil effector programs is unclear. We investigated whether..

Perfusfind S.L.

Abstract BACKGROUND: Acute kidney injury (AKI) is a common and severe complication after cardiac surgery with cardiopulmonary bypass (CPB). Experimental data suggest that increasing CPB flow beyond standard targets may..

Perfusfind S.L.

Abstract Objectives Low haematocrit during cardiopulmonary bypass is a known risk factor for acute kidney injury, but it is unclear whether high haematocrit also increases acute kidney injury risk. We..

Perfusfind S.L.

Abstract Objectives Cardiopulmonary bypass (CPB) priming may influence haemodilution, bleeding, and end-organ injury during HeartMate 3 (HM3) implantation, but evidence in contemporary left ventricular assist device (LVAD) surgery is limited...

Perfusfind S.L.

Abstract Background: Hemoperfusion has emerged as a potential extracorporeal blood purification strategy for attenuating inflammation during cardiopulmonary bypass (CPB), but perioperative biomarker trajectory data remain limited. This pilot comparative study..

Perfusfind S.L.

Abstract Background and Objectives: Prolonged intensive care unit (ICU) stay following coronary artery bypass grafting (CABG) remains a major clinical challenge. The aim of this study was to identify preoperative..

Perfusfind S.L.

Abstract Objectives To determine the probability of a clinically relevant reduction in postoperative myocardial injury following the use of propofol-supplemented cardioplegia. Design Systematic review and Bayesian meta-analysis. Setting Perioperative cardiac..

Perfusfind S.L.

Abstract Background In mitral valve surgery, cardioplegia is commonly dosed by body weight or body surface area (BSA), which may not reflect true cardiac mass. We evaluated whether indexing the..

Perfusfind S.L.

Abstract Failure to wean from cardiopulmonary bypass (CPB) is a rare but critical intraoperative challenge. Common causes include residual structural defects (causing intracardiac shunting, prosthetic valve leaks), left ventricle outflow..

Perfusfind S.L.

Abstract Factor XIII (FXIII) is the final enzyme in the coagulation cascade that cross-links the fibrin monomers, thereby enhancing the clot strength. Congenital FXIII deficiency is rare and is inherited..

Perfusfind S.L.

Abstract INTRODUCTION: Femoral venous cannulation is widely used to establish cardiopulmonary bypass (CPB) during minimally invasive cardiac surgery (MICS). Although transesophageal echocardiography (TEE) is commonly used to guide cannula placement, cannula..

Perfusfind S.L.

Abstract Background: Hemolytic complications remain a major limitation of membrane oxygenators in clinical support. Compared with human lungs, most commercial oxygenators generate substantial pressure drops and high shear stress, increasing..

Perfusfind S.L.

Abstract Objective To describe postoperative outcomes with the use of partial CPB for thoracoabdominal aortic repair. Methods We included all the patients who underwent programmed thoracoabdominal aortic procedures in which..

Perfusfind S.L.

Abstract Background There is limited clinical data to guide surgical decisions for ACC with extensive carinal involvement in the left main bronchus. In this case, it is shown that median..

Perfusfind S.L.

Abstract Background: The clinical benefits of pulsatile perfusion during cardiopulmonary bypass (CPB) remain a subject of debate. This study aimed to compare clinical outcomes between pulsatile and non-pulsatile perfusion during..

Perfusfind S.L.

Abstract Background: Hemodilution during cardiopulmonary bypass (CPB) is a standard perfusion strategy used to reduce blood viscosity and enhance microcirculatory flow. The hemodilution rate, expressed as hemoglobin (Hb) concentration, is..

Perfusfind S.L.

Abstract Objective To evaluate the relationship between cardiopulmonary bypass (CPB) duration, change in thoracic fluid content (ΔTFC) measured using electrical cardiometry, and postoperative oxygenation in infants undergoing ventricular septal defect..

Perfusfind S.L.

Abstract Imagine, for a moment, that targeted temperature management (TTM), the standard of care in post cardiac arrest management for more than two decades, was built on a false premise..

Perfusfind S.L.

Abstract Background We aimed to clarify the changes in sevoflurane blood concentrations in cardiovascular surgeries with cardiopulmonary bypass (CPB) under mild to moderate hypothermia. Methods In this single-center, prospective observational..

Perfusfind S.L.

Abstract Background: Cardiopulmonary bypass (CPB) is a cornerstone of modern cardiac surgery, requiring continuous, high stakes decision making based on rapidly evolving physiological and technical parameters. Despite advances in perfusion..

Perfusfind S.L.

Abstract Background Cardiopulmonary bypass (CPB) is essential in open-heart surgery but is associated with systemic inflammatory response syndrome and organ-specific complications, which can worsen patient outcomes. In low-resource settings, limited..

Perfusfind S.L.

Abstract High-pressure excursions (HPE) during cardiopulmonary bypass (CPB) are rare but potentially life-threatening events linked to coagulation activation, inflammation. Known risk factors include male sex, large body surface area (BSA),..

Perfusfind S.L.

Abstract Objectives To compare myocardial protection afforded by three single-dose cardioplegic solutions — Custodiol (HTK), del Nido (DN) and modified del Nido (MDN) — in adult elective cardiac surgery. Design Double-blind randomised..

Perfusfind S.L.

Abstract Background: Discussions continue on the ideal priming fluid in adult cardiac surgery. The purpose of this prospective study was to evaluate the effects of different types of priming fluids..

Perfusfind S.L.

Abstract Background While hyperoxia has conventionally been the standard during cardiopulmonary bypass (CPB) to prevent hypoxemia, recent concerns regarding oxygen-induced oxidative stress have sparked debate over whether a normoxic strategy..

Perfusfind S.L.

Abstract Introduction: Providing sufficient organ perfusion during cardiopulmonary bypass (CPB) is a common research topic among extracorporeal technology researchers. The application of an elevated cardiac index (CI) to enhance CPB..

Perfusfind S.L.

Abstract Background Ultrafiltration is integral to cardiopulmonary bypass, yet the optimal replacement fluid for zero-balance ultrafiltration requires further investigation to guide clinical practice. This study aimed to compare the efficacy..

Perfusfind S.L.

Abstract Background Cardiopulmonary bypass (CPB) oxygenators provide essential intra-operative gas exchange. Although rare, CPB oxygenator failures can cause catastrophic morbidity and mortality, and published analyses of CPB-specific oxygenator failures are..

Perfusfind S.L.

Abstract Objectives Cardiopulmonary bypass (CPB) impairs endothelial function, causing oedema and disturbed microcirculatory perfusion, that contribute to organ dysfunction following cardiac surgery. We hypothesised that the composition of CPB prime..