Serum lactate is a critical biomarker in cardiac surgery, offering insights into tissue oxygenation and metabolic status. Elevated lactate levels during cardiopulmonary bypass (CPB) can indicate inadequate perfusion, hypoxia, or..
Read MoreAbstract Background: Minimizing Gaseous microemboli (GME) introduced into the CPB circuit can help alleviate neurologic injury. This study focuses on understanding how suction flow rate and the reservoir level can..
Read MoreAbstract Background: The accuracy and precision of continuous in-line blood gas monitoring (CILBGM) are crucial for optimal blood gas management during cardiopulmonary bypass (CPB) and improved patient outcomes. CILBGM devices,..
Read MoreAbstract Objectives This study aimed to evaluate the hemodynamic impact and cost-effectiveness of a standardized protocol for refractory vasoplegia occurring after cardiopulmonary bypass (CPB). Design Observational, pre-post study. Setting A..
Read MoreAbstract Introduction: Despite the advances in CPB, various complications may occur. Prediction and anticipation of these undesirable outcomes is of great importance. For this reason, various markers have been tried to..
Read MoreAbstract The administration of cardioplegia is a core component of the multimodal approach to myocardial protection during cardiac surgery with cardiopulmonary bypass., An ideal cardioplegia solution should facilitate rapid cardiac arrest,..
Read MoreAbstract Introduction: During cardiopulmonary bypass (CPB), adequate prime solution allows pre-treatment of the tubing line, oxygenator and blood pump, evacuation of air from the arterial conduit, and appropriate blood dilution. However,..
Read MoreAbstract Objective Near Infra-Red Spectroscopy (NIRS), can be used to monitor renal tissue oxygenation (SrO2), as well as thenar muscle oxygenation (SmO2). In this study, we have examined the ability of..
Read MoreAbstract Introduction: In patients undergoing cardiopulmonary bypass-guided cardiac surgery, knowledge of the preoperative effects of platelet distribution width (PDW), red cell distribution width - standard deviation (RDW-SD), and platelet large cell..
Read MoreAbstract Introduction: Although the use of the heart-lung machine (HLM) is routine in cardiac operating theaters, there is still a lack of evidence-based guidelines concerning the optimal speed to reach..
Read MoreAbstract Cardiopulmonary bypass (CPB) is an essential component of modern cardiac surgery, allowing surgeons to temporarily replace heart and lung function during complex procedures. One important technical aspect of CPB..
Read MoreAbstract Introduction Delirium is a common, distressing, and dangerous complication after cardiac surgery with cardiopulmonary bypass (CPB) with few modifiable risk factors. This study aims to determine the association between..
Read MoreAbstract Background Nitric oxide (NO) is reported to play several protective roles in the inflammatory response and ischemia/reperfusion injury. This study evaluated the effect of nitric oxide (NO) on postoperative..
Read MoreAbstract Endothelin-1 is a potent regulator of vasomotor tone and promotes endothelium-dependent vasoconstriction of vascular smooth muscle. Dysregulated vasomotor tone is a hallmark of microvascular pathology following cardiac surgery involving..
Read MoreAbstract Background The purpose of this descriptive study was to characterize the utilization and outcomes of CPB after trauma. Methods This is an AAST-sponsored retrospective (2011-2021) multicenter (32 centers) study..
Read MoreAbstract Background/Objectives: Cardiopulmonary bypass (CPB) facilitates complex cardiac surgery but can damage erythrocyte membranes, impairing microcirculation and oxygen transport. Standard rheological tests assess overall blood properties but fail to define..
Read MoreAbstract Objective: To compare the effects of intermittent classical blood cardioplegia and single-dose modified Del Nido cardioplegia on postoperative serum lactate levels and extubation time in patients undergoing coronary artery bypass..
Read MoreAbstract Background Acute aortic dissection of the ascending aorta is a life-threatening disease that poses a significant challenge for cardiovascular surgeons. Dissection of the aorta typically occurs when the aortic..
Read MoreAbstract Objectives To test the hypotheses that intraoperative hyperlactatemia is independently associated with increased postoperative infection risk in cardiac surgery with cardiopulmonary bypass (CPB). Methods This study involved 4970 cardiac..
Read MoreAbstract Objectives To evaluate the efficacy of intraoperative hemoadsorption (HA) during cardiopulmonary bypass (CPB) in reducing acute kidney injury (AKI) and other major postoperative complications in patients undergoing cardiac surgery...
Read MoreAbstract Purpose Cardiopulmonary bypass (CPB) is a well-established procedure that uses cannulae during cardiac surgery to drain and return blood. In challenging cases (e.g. aortic dissection, reoperation), peripheral cannulation in..
Read MoreAbstract Background Heparin is commonly administered to prevent thrombosis during cardiopulmonary bypass (CPB). However, the development of intracardiac thrombi under CPB has still been reported. Case summary A 79-year-old man..
Read MoreAbstract Malignant hyperthermia (MH) is a rare but potentially fatal disorder characterized by a hypermetabolic state produced by exposure to triggering agents such as volatile anesthetics and succinylcholine., MH crises have..
Read MoreAbstract Background Advances in medicine lead to an increase in the number of patients with concurrent heart disease and cancer. We investigated the effect of cardiac surgery under cardiopulmonary bypass..
Read MoreAbstract Objectives This study hypothesizes that induced hypothermia (IH) can safely extend aortic cross-clamp (ACC) time, significantly reducing metabolic burden and end-organ injury, thereby enabling more comprehensive aortic arch reconstructions..
Read MoreAbstract Cardiopulmonary bypass (CPB) is one of the most groundbreaking medical innovations in history, enabling safe and effective heart surgery by temporarily replacing the function of the heart and lungs...
Read MoreAbstract Objectives Cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO) or life support (ECLS) circuits are built from polymers and might release polymeric micro- and nanoparticles (MNP) into the circulation...
Read MoreAbstract Background During cardiac surgery the use of a minimal extracorporeal circulation (MiECC) system may reduce the adverse effects for the patient. This is probably caused by reduced inflammation and..
Read MoreAbstract BACKGROUND The choice of priming and volume replacement fluids during cardiopulmonary bypass (CPB) in cardiac surgery impacts hemodynamic stability, coagulation, renal function, and patient outcomes. Hydroxyethyl starch (HES) 130/0.4..
Read MoreAbstract Objectives The central cannulation technique was introduced at our institution in 2018 and has evolved into a primary cannulation strategy for acute type A aortic dissection (ATAAD) surgery. This..
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