Archives

Perfusfind S.L.

Abstract Heparin is the primary anticoagulant used for cardiopulmonary bypass and requires reversal to prevent postoperative bleeding. Protamine sulfate is the only United States Food and Drug Administration–approved heparin reversal..

Perfusfind S.L.

Abstract Purpose To assess the effects of conventional ultrafiltration and conventional plus zero-balanced ultrafiltration on delirium and cognition in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods A total..

Perfusfind S.L.

Abstract Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and cardiopulmonary bypass (CPB) are used during pediatric heart surgery to provide cardiopulmonary support to patients as they undergo and recover from surgical..

Perfusfind S.L.

Abstract OBJECTIVES:  Vasoplegia is a common complication of cardiac surgery that uses cardiopulmonary bypass and contributes to morbidity and mortality, yet a consensus definition does not exist. The objective of..

Perfusfind S.L.

Abstract Purpose: Cryoprecipitate has been covered by Japanese national health insurance since 2020 for cardiopulmonary bypass (CPB)-induced hypofibrinogenemia. This study evaluated the clinical efficacy of in-house cryoprecipitate use in patients..

Perfusfind S.L.

Abstract Background/Objectives: Whether a remote history of SARS-CoV-2 infection independently affects early haemodynamic stability after elective cardiopulmonary bypass (CPB) remains uncertain. We evaluated whether prior COVID-19 (>7 weeks before surgery)..

Perfusfind S.L.

Abstract Background Elevated central venous pressure during cardiac surgery can lead to increased renal venous pressure, subsequently resulting in renal insufficiency. However, there is a lack of animal models available..

Perfusfind S.L.

Abstract Separation from cardiopulmonary bypass (CPB) is a critical phase of cardiac surgery, particularly in patients with pulmonary hypertension and right heart failure. Milrinone, a phosphodiesterase inhibitor, is often used..

Perfusfind S.L.

Abstract Introduction Vacuum-assisted venous drainage (VAVD) has been proposed as a better alternative option than conventional gravitational venous drainage (GVD) in cardiac surgery. However, the literature reports conflicting results between..

Perfusfind S.L.

Abstract Background Goal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) commonly targets indexed oxygen delivery (DO2i), yet fixed delivery thresholds may ignore patient-specific metabolic demand. The oxygen extraction ratio (O2ER) integrates..

Perfusfind S.L.

Abstract Background Although delivering less oxygen is associated with acute kidney injury, little is known about its association with long-term mortality and how the association may be modified by transfusion...

Perfusfind S.L.

Abstract Background and clinical significance. Penetrating cardiothoracic wounds require prompt treatment in order to decrease mortality and morbidity. Surgical therapy, aimed at bleeding control and removal of damaged tissue, varies widely..

Perfusfind S.L.

Abstract In extracorporeal life support and perfusion, progress has rarely followed the neat, linear hierarchy of evidence promoted by traditional evidence-based medicine. The randomized controlled trial (RCT) remains the proclaimed..

Perfusfind S.L.

Abstract Introduction: The use of cardiopulmonary bypass (CPB) is necessary during the repair of most congenital heart disease (CHD). The surface area of the CPB circuit and the volume of..

Perfusfind S.L.

Abstract Background Cardiopulmonary bypass (CPB) plays a crucial role in cardiac surgery, with the pump being a key component affecting both hemolysis and thrombosis. Centrifugal levitating pumps (CP) have demonstrated..

Perfusfind S.L.

Abstract Real-time, quantitative biosensing within extracorporeal perfusion (ECP) and extracorporeal membrane oxygenation (ECMO) systems is key to advancing this life-support technology beyond the hospital setting to emergency care. Measuring and..

Perfusfind S.L.

Abstract Introduction Intra-operative hypotension is common during cardiopulmonary bypass and may contribute to tissue hypoxia. Tissue hypoxia has been linked to the development of postoperative kidney and brain injury. Vasopressors..

Perfusfind S.L.

Abstract Objectives Maintaining a nadir oxygen delivery ≥ 280 mL/min/m2 during cardiopulmonary bypass is a pillar of the goal-directed perfusion strategy in cardiac surgery. However, there are patients who develop a..

Perfusfind S.L.

Abstract Objective To explore the factors affecting patient outcomes in pulmonary artery thromboendarterectomy (PTE) under deep hypothermic circulatory arrest (DHCA) and cardiopulmonary bypass (CPB) support and to provide a reference..

Perfusfind S.L.

Abstract Managing severe  (AS) alongside complex  (CAD) in frail patients is challenging. A 79-year-old female with resting dyspnea was diagnosed with severe AS and CAD. While  (CABG) was the appropriate treatment for CAD,..

Perfusfind S.L.

Abstract Background Pulsatile perfusion is a developing technique that attempts to mimic the natural pulsatile flow of blood during cardiopulmonary bypass (CBP). Purpose This systematic review and meta-analysis was conducted..

Perfusfind S.L.

Abstract Introduction Perfusion accidents still threaten the safety of perfusion during open-heart surgery. To prevent these accidents and increase perfusion safety, it is important to first determine the profile of..

Perfusfind S.L.

Abstract Objective: Coronary artery bypass grafting using cardiopulmonary bypass and cardioplegic arrest is an effective treatment for coronary artery disease. Research suggests supplementing the cardioplegia solution with propofol may be..

Perfusfind S.L.

Abstract Background Cardiopulmonary bypass is widely used in cardiac surgery but often leads to lung ischemia–reperfusion injury, a major cause of morbidity and mortality. Despite advances in critical care, effective..

Perfusfind S.L.

Abstract Background Cardiopulmonary bypass (CPB) during cardiac surgery disrupts cerebral hemodynamics, potentially leading to postoperative neurological complications such as delirium. Transcranial Doppler (TCD) offers non-invasive monitoring of cerebral blood flow..

Perfusfind S.L.

Abstract Background/Aim Recent literature suggested that the use of Minimal Invasive Extracorporeal Circulation (MIECC) may mitigate the inflammatory response in patients undergoing cardiac surgery. We aimed to perform a meta-analysis..

Perfusfind S.L.

Abstract Introduction Blood damage during cardiopulmonary bypass can trigger postoperative inflammatory responses and organ injury. Therefore, optimizing the blood circuit design to minimize damage remains essential. However, variations in venous..

Perfusfind S.L.

Abstract Cardiopulmonary bypass (CPB) is one of the most groundbreaking medical innovations in history, enabling safe and effective heart surgery by temporarily replacing the function of the heart and lungs...

Perfusfind S.L.

Abstract Objectives Systemic inflammatory response syndrome (SIRS) is a common complication following cardiopulmonary bypass (CPB), associated with increased mortality. We assessed the relationship between indexed oxygen delivery (DO2i) during CPB..

Perfusfind S.L.

Abstract Background: Low hematocrit level is a hematological problem that is frequently encountered during cardiopulmonary bypass (CPB) in patients undergoing on-pump coronary artery bypass grafting (CABG). This study aimed to..