Yearly Archives: 2026

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Comparison of myocardial cooling effects between antegrade and retrograde cardioplegia: a retrospective study using thermography

Abstract Background Cardioplegia is delivered via antegrade, retrograde, or combined perfusion routes. Antegrade cardioplegia follows the physiological path but may be less effective in patients with severe coronary disease. Retrograde..

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Redefining the role of perfusionists in ECMO: from technical operators to clinical stakeholders

Abstract Extracorporeal Membrane Oxygenation (ECMO) is increasingly used in refractory cardiac and respiratory failure, yet the role of perfusionists remains narrowly defined. While traditionally viewed as technical operators, perfusionists possess..

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What is the ideal solution for washing salvaged red blood cells using a cell saver for autotransfusion during surgery

Abstract There are three reasons why perfusionists and autotransfusionists around the globe still use Normal Saline with cell savers; (1) This what they were taught by their peers and/or didactic..

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Peripheral veno-arterial ECMO cannulation in children: Review of the relevant ELSO publications

Abstract Background Peripheral veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) cannulation in children poses a significant clinical challenge due to wide variations in body size, vessel caliber, and risk profiles. Purpose..

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Use of Andexanet Alfa to Reverse Heparin After Cardiopulmonary Bypass

Abstract Heparin is the primary anticoagulant used for cardiopulmonary bypass and requires reversal to prevent postoperative bleeding. Protamine sulfate is the only United States Food and Drug Administration–approved heparin reversal..

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ISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation: Part III: Postoperative Considerations

Abstract The use of extracorporeal life support (ECLS) throughout the perioperative phase of lung transplantation requires nuanced planning and execution by an integrated team of multidisciplinary experts. To date, no..

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Getinge’s ECMO simulation Global Webinar

Getinge's ECMO Simulation Global Webinar During this webinar, live participants will have the opportunity to test and enhance their ECMO knowledge by engaging in an interactive eCPR scenario using Pratico Santé’s..

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Leveraging the perfusionist-surgeon dyad to improve the culture of safety

Abstract The cardiac surgical operating room is a complex, high risk environment dependent on efficient teamwork and communication between multiple role groups to deliver safe and effective care. As awareness..

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Mitral Valve Surgery for Rheumatic Heart Disease in Indigenous Australians: A 27-Year Cohort Study of Repair Versus Replacement Outcomes

Abstract Aim This study aimed to evaluate long-term outcomes of mitral valve surgery for rheumatic heart disease (RHD) in Indigenous Australians, comparing survival and revision rates between valve repair and..

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Survival on the clock: rethinking where and how we deliver ECPR

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) is the only therapy capable of rescuing patients from refractory cardiac arrest, but its effectiveness is critically dependent on time to reperfusion. The system proposed..

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Zero-Balance Ultrafiltration Reduces Postoperative Delirium After Cardiac Surgery with Cardiopulmonary Bypass: A Randomized Controlled Trial

Abstract Purpose To assess the effects of conventional ultrafiltration and conventional plus zero-balanced ultrafiltration on delirium and cognition in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods A total..

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Extracorporeal Cardiopulmonary Resuscitation and Organ Donation: A Modified Delphi Study Exploring Cumulative Impact Index Feasibility

Abstract Although the goal of extracorporeal cardiopulmonary resuscitation (ECPR) remains survival with meaningful neurologic recovery, secondary contribution to organ donation is increasingly recognized. We identified standardized outcome metrics for quality..

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Impact of rhythm changes during CPR on ECPR outcomes: an ELSO Registry study

Abstract Background Cardiac rhythm is a well-established prognostic factor in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR); however, existing evidence is primarily limited to small, single-center studies. This study aimed to..

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Outcomes of Venopulmonary Extracorporeal Membrane Oxygenation Conversion in Patients With Severe Respiratory Failure on Venovenous Support

Abstract Severe respiratory failure is frequently complicated by right ventricular dysfunction (RVD), which occurs in 20–50% of cases. In patients on venovenous extracorporeal membrane oxygenation (VV ECMO) with refractory RVD,..

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Heparin Resistance in Cardiac Surgery with Cardiopulmonary Bypass: Mechanisms, Clinical Implications, and Evidence-Based Management

Abstract Background: Unfractionated heparin (UFH) is the standard anticoagulant during cardiopulmonary bypass (CPB). A clinically relevant subset develops heparin resistance (HR)—failure to reach adequate anticoagulation with usual UFH—raising thrombotic risk..

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Antimicrobial pharmacokinetics and stewardship in critically Ill adult patients receiving ECMO: Challenges, evidence, and future directions

Abstract Infection is a common indication and complication for extracorporeal membrane oxygenation (ECMO), and adult ECMO recipients face increased nosocomial infection risk. Effective antimicrobial dosing in these patients remains difficult..

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Effects of hyperoxia in pediatric perfusion patients: a scoping review

Abstract Hyperoxia in pediatric cardiopulmonary bypass patients is associated with adverse effects, including reoxygenation injury, increased mortality, heightened inflammatory response, and cerebral injury. Although prior research has demonstrated a correlation..

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ECMO to CPB: A single circuit approach

Abstract Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and cardiopulmonary bypass (CPB) are used during pediatric heart surgery to provide cardiopulmonary support to patients as they undergo and recover from surgical..

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Growth and neurodevelopment at 18–22 months in term infants with CHD undergoing cardiopulmonary bypass surgery: a retrospective cohort study

Abstract Background:Infants with CHD who undergo cardiopulmonary bypass surgery are at risk of impaired growth and neurodevelopment. However, few studies have thoroughly investigated the risk factors for growth and neurodevelopmental..

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Definitions for Vasoplegia Associated With On-Pump Cardiac Surgery: A Systematic Review With Meta-Analysis

Abstract OBJECTIVES:  Vasoplegia is a common complication of cardiac surgery that uses cardiopulmonary bypass and contributes to morbidity and mortality, yet a consensus definition does not exist. The objective of..

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Cold-stored platelets: A systematic review of recovery in healthy adults and chest drain output in cardiothoracic surgery patients

Abstract Cold-stored platelets were abandoned in the 1960s after demonstration of an increased clearance in vivo due to an irreversible activated phenotype. Difficulties in storage, logistics, and the increased requirement..

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Associations between baseline cerebral oxygen saturation, preoperative B-type natriuretic peptide and hemoglobin levels, and mortality after cardiac surgery in non-dialysis…

Abstract Baseline cerebral regional oxygen saturation (rSO₂) measured with the INVOS 5100C near-infrared spectroscopy (NIRS) device has been reported to correlate primarily with preoperative B-type natriuretic peptide (BNP) and hemoglobin..

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Effects of intraoperative cell salvage versus preoperative autologous blood donation on postoperative coagulation in cardiac surgery

Abstract  Objective: To compare the effects of intraoperative cell salvage (ICS) and preoperative autologous blood donation (PABD) on postoperative coagulation and platelet function in patients undergoing cardiac surgery, and to..

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Improving urinary oxygen monitoring with a transit time algorithm: enhancing AKI detection in cardiac surgery

Abstract Acute kidney injury (AKI) affects 40–50% of cardiac surgery patients and is closely linked to renal medullary hypoxia. Although urinary oxygen partial pressure (PuO2) offers real-time insight into renal..

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Explainable machine learning models for early prediction of acute kidney injury after cardiac surgery

Abstract Background This study aimed to develop a data-driven prediction model for cardiac surgery-associated acute kidney injury (CSA-AKI) at the end of surgery using machine learning (ML) algorithms. Methods We..

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Developing a faculty simulation-based education strategy: a Delphi study to build consensus and aid decision making

Abstract Background Simulation-based education (SBE) improves learner competence, patient safety and workforce readiness. Yet, existing frameworks such as INACSL and ASPiH provide limited guidance on developing sustainable, institution-wide strategies, particularly..

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Cost-Effectiveness of Cryopreserved vs Liquid-Stored Platelets for Managing Surgical Bleeding

Abstract Importance  Platelet transfusion is critical in managing major bleeding, but access to liquid-stored platelets is limited by their 5- to 7-day shelf life. Cryopreserved platelets last up to 2 years..

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Reduced risk of perioperative blood transfusions in coronary surgery: A nationwide study over 18 years

Abstract Background Coronary artery bypass grafting (CABG) carries a high risk of bleeding and allogeneic blood transfusions, both associated with poor outcomes. We assessed perioperative transfusions and factors associated with..

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Optimized Extracorporeal Perfusion Strategy: A New Concept

Abstract Optimized Extracorporeal Perfusion Strategy: A New Concept Early heart-lung machines were mechanically simple, with rudimentary monitoring capabilities, and caused pronounced physiological disturbances due to large priming volumes and uncoated..

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From Deep Hypothermia to Goal-Directed Perfusion: Contemporary Insights Into Perfusion Techniques for Pulmonary Endarterectomy, Including a Narrative Review and Perspectives

Abstract Pulmonary endarterectomy (PEA) remains the curative surgical option for chronic thromboembolic pulmonary hypertension (CTEPH), a condition requiring precise cardiopulmonary bypass (CPB) management to balance cerebral protection, myocardial preservation, and..

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