Abstract Background Cardioplegia is delivered via antegrade, retrograde, or combined perfusion routes. Antegrade cardioplegia follows the physiological path but may be less effective in patients with severe coronary disease. Retrograde..
Read MoreAbstract Extracorporeal Membrane Oxygenation (ECMO) is increasingly used in refractory cardiac and respiratory failure, yet the role of perfusionists remains narrowly defined. While traditionally viewed as technical operators, perfusionists possess..
Read MoreAbstract There are three reasons why perfusionists and autotransfusionists around the globe still use Normal Saline with cell savers; (1) This what they were taught by their peers and/or didactic..
Read MoreAbstract Background Peripheral veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) cannulation in children poses a significant clinical challenge due to wide variations in body size, vessel caliber, and risk profiles. Purpose..
Read MoreAbstract Heparin is the primary anticoagulant used for cardiopulmonary bypass and requires reversal to prevent postoperative bleeding. Protamine sulfate is the only United States Food and Drug Administration–approved heparin reversal..
Read MoreAbstract The use of extracorporeal life support (ECLS) throughout the perioperative phase of lung transplantation requires nuanced planning and execution by an integrated team of multidisciplinary experts. To date, no..
Read MoreGetinge's ECMO Simulation Global Webinar During this webinar, live participants will have the opportunity to test and enhance their ECMO knowledge by engaging in an interactive eCPR scenario using Pratico Santé’s..
Read MoreAbstract The cardiac surgical operating room is a complex, high risk environment dependent on efficient teamwork and communication between multiple role groups to deliver safe and effective care. As awareness..
Read MoreAbstract Aim This study aimed to evaluate long-term outcomes of mitral valve surgery for rheumatic heart disease (RHD) in Indigenous Australians, comparing survival and revision rates between valve repair and..
Read MoreAbstract Extracorporeal cardiopulmonary resuscitation (ECPR) is the only therapy capable of rescuing patients from refractory cardiac arrest, but its effectiveness is critically dependent on time to reperfusion. The system proposed..
Read MoreAbstract Purpose To assess the effects of conventional ultrafiltration and conventional plus zero-balanced ultrafiltration on delirium and cognition in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods A total..
Read MoreAbstract Although the goal of extracorporeal cardiopulmonary resuscitation (ECPR) remains survival with meaningful neurologic recovery, secondary contribution to organ donation is increasingly recognized. We identified standardized outcome metrics for quality..
Read MoreAbstract Background Cardiac rhythm is a well-established prognostic factor in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR); however, existing evidence is primarily limited to small, single-center studies. This study aimed to..
Read MoreAbstract Severe respiratory failure is frequently complicated by right ventricular dysfunction (RVD), which occurs in 20–50% of cases. In patients on venovenous extracorporeal membrane oxygenation (VV ECMO) with refractory RVD,..
Read MoreAbstract Background: Unfractionated heparin (UFH) is the standard anticoagulant during cardiopulmonary bypass (CPB). A clinically relevant subset develops heparin resistance (HR)—failure to reach adequate anticoagulation with usual UFH—raising thrombotic risk..
Read MoreAbstract Infection is a common indication and complication for extracorporeal membrane oxygenation (ECMO), and adult ECMO recipients face increased nosocomial infection risk. Effective antimicrobial dosing in these patients remains difficult..
Read MoreAbstract Hyperoxia in pediatric cardiopulmonary bypass patients is associated with adverse effects, including reoxygenation injury, increased mortality, heightened inflammatory response, and cerebral injury. Although prior research has demonstrated a correlation..
Read MoreAbstract Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and cardiopulmonary bypass (CPB) are used during pediatric heart surgery to provide cardiopulmonary support to patients as they undergo and recover from surgical..
Read MoreAbstract Background:Infants with CHD who undergo cardiopulmonary bypass surgery are at risk of impaired growth and neurodevelopment. However, few studies have thoroughly investigated the risk factors for growth and neurodevelopmental..
Read MoreAbstract OBJECTIVES: Vasoplegia is a common complication of cardiac surgery that uses cardiopulmonary bypass and contributes to morbidity and mortality, yet a consensus definition does not exist. The objective of..
Read MoreAbstract Cold-stored platelets were abandoned in the 1960s after demonstration of an increased clearance in vivo due to an irreversible activated phenotype. Difficulties in storage, logistics, and the increased requirement..
Read MoreAbstract Baseline cerebral regional oxygen saturation (rSO₂) measured with the INVOS 5100C near-infrared spectroscopy (NIRS) device has been reported to correlate primarily with preoperative B-type natriuretic peptide (BNP) and hemoglobin..
Read MoreAbstract Objective: To compare the effects of intraoperative cell salvage (ICS) and preoperative autologous blood donation (PABD) on postoperative coagulation and platelet function in patients undergoing cardiac surgery, and to..
Read MoreAbstract Acute kidney injury (AKI) affects 40–50% of cardiac surgery patients and is closely linked to renal medullary hypoxia. Although urinary oxygen partial pressure (PuO2) offers real-time insight into renal..
Read MoreAbstract Background This study aimed to develop a data-driven prediction model for cardiac surgery-associated acute kidney injury (CSA-AKI) at the end of surgery using machine learning (ML) algorithms. Methods We..
Read MoreAbstract Background Simulation-based education (SBE) improves learner competence, patient safety and workforce readiness. Yet, existing frameworks such as INACSL and ASPiH provide limited guidance on developing sustainable, institution-wide strategies, particularly..
Read MoreAbstract Importance Platelet transfusion is critical in managing major bleeding, but access to liquid-stored platelets is limited by their 5- to 7-day shelf life. Cryopreserved platelets last up to 2 years..
Read MoreAbstract Background Coronary artery bypass grafting (CABG) carries a high risk of bleeding and allogeneic blood transfusions, both associated with poor outcomes. We assessed perioperative transfusions and factors associated with..
Read MoreAbstract Optimized Extracorporeal Perfusion Strategy: A New Concept Early heart-lung machines were mechanically simple, with rudimentary monitoring capabilities, and caused pronounced physiological disturbances due to large priming volumes and uncoated..
Read MoreAbstract Pulmonary endarterectomy (PEA) remains the curative surgical option for chronic thromboembolic pulmonary hypertension (CTEPH), a condition requiring precise cardiopulmonary bypass (CPB) management to balance cerebral protection, myocardial preservation, and..
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