Yearly Archives: 2026

Perfusfind S.L.

Abstract Background:  Static or averaged electroencephalography (EEG) metrics may fail to capture dynamic cerebral changes during surgery. We assessed the EEG features during aortic arch surgery with cardiopulmonary bypass (CPB)..

Perfusfind S.L.

Abstract Objective Postoperative days alive and out of hospital within 30 days (DAH-30) is a validated, patient-centered metric reflecting the quality of care and recovery after surgery. This study aimed..

Perfusfind S.L.

Abstract Background Cardiogenic shock (CS) is a severe complication of ST-elevation myocardial infarction (STEMI) with high mortality despite advancements in treatment. Mechanical circulatory support (MCS) devices, such as extracorporeal membrane..

Perfusfind S.L.

Abstract Lactate has traditionally been framed as a by-product of anaerobic metabolism and a surrogate for tissue hypoxia. Contemporary physiology recasts lactate as a central fuel, shuttle, and signaling molecule,..

Perfusfind S.L.

Abstract Blood clots are pivotal for haemostasis and regeneration, but they are mechanically weak and form slowly, posing risks for life-threatening haemorrhage and limiting broader applications,,. These limitations are attributed..

Perfusfind S.L.

Abstract Objective Vasoplegia and endothelial dysfunction are well-known complications of cardioplegia and cardiopulmonary bypass (CP/CPB). Our lab has previously shown that endothelial adherens junction impairment is driven by vascular endothelial..

Perfusfind S.L.

Abstract BACKGROUND:  Penetrating cardiac injuries caused by firearms are associated with extremely high prehospital and early in-hospital mortality. During wartime, civilian cardiac surgery centers are increasingly involved in the management..

Perfusfind S.L.

Abstract Background Patients supported with extracorporeal membrane oxygenation (ECMO) are susceptible to healthcare-associated infections (HAIs), which may worsen outcomes. However, epidemiological data from Latin American centres remain scarce. Methods We..

Perfusfind S.L.

Abstract In cardiogenic shock (CS), blood lactate concentration is routinely used to assess shock severity and guide clinical decisions. However, lactate interpretation is often oversimplified, leading to confusion between disease..

Perfusfind S.L.

Abstract Congenital heart disease often requires early surgical intervention. Cardiopulmonary bypass (CPB) is a standard procedure, but infants undergoing CPB show an increased risk of postoperative white matter injury. These..

Perfusfind S.L.

Abstract Although extracorporeal membrane oxygenation (ECMO) has emerged as a pivotal temporary extracorporeal life support in critically ill patients, it is associated with a high risk of mortality. Establishing a..

Perfusfind S.L.

Abstract Objective To characterize relationships between social determinants of health (SDoH) and mortality among infants receiving extracorporeal membrane oxygenation (ECMO). Study design Retrospectively, we identified infants born >34weeks gestation and..

Perfusfind S.L.

Abstract We present the first characterization of multiple organ dysfunction (OD) patterns and their associations with in-hospital mortality for children on extracorporeal membrane oxygenation (ECMO). We retrospectively assessed OD for..

Perfusfind S.L.

Abstract Acute kidney injury (AKI) and fluid accumulation (FA) are common during extracorporeal membrane oxygenation (ECMO) support and are associated with increased morbidity and mortality. Despite their clinical importance, contemporary..

Perfusfind S.L.

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for refractory paediatric in-hospital cardiac arrest (IHCA). Although rapid initiation of extracorporeal life support (ECLS) is widely considered critical, the relative..

Perfusfind S.L.

Abstract Intraoperative adverse events (IAEs) are a significant unresolved problem in surgery. Breakdown in nontechnical skills (NTS) of surgical team members are a significant contributor to preventable IAEs [], Surgical..

Perfusfind S.L.

Abstract Artificial intelligence (AI) has rapidly emerged as a transformative force across multiple scientific and clinical domains, demonstrating remarkable capabilities in data analysis, pattern recognition, and predictive modeling. In the..

Perfusfind S.L.

Abstract Background Extracorporeal circulation (ECC) is increasingly supported by biomaterials engineered to minimize chemical leaching, and many biomedical manufacturers have now removed or substantially reduced phthalate plasticizers particularly di(2-ethylhexyl) phthalate..

Perfusfind S.L.

Abstract Background Acute kidney injury is a common complication of cardiac surgery and may lead to kidney failure. In a large sample sourced from national registries, we estimated the risk..

Perfusfind S.L.

Abstract Introduction Bleeding and clotting phenotypes are common in patients supported with Extracorporeal Membrane Oxygenation (ECMO) and are associated with increased mortality. However, tools to distinguish bleeding from clotting phenotypes..

Perfusfind S.L.

Abstract Factor XIII (FXIII) contributes to clot stability and reduces clot susceptibility to lysis through fibrin cross-linking. Standard coagulation tests like prothrombin time and activated partial thromboplastin time do not..

Perfusfind S.L.

Abstract Background and Objectives: Overt perioperative stroke remains a feared complication of adult cardiac surgery. Diffusion-weighted magnetic resonance imaging (DWI-MRI) has revealed a more prevalent form of cerebral injury, termed..

Perfusfind S.L.

Abstract Decompensated differential carbon dioxide (CO2) removal can occur during spontaneous breathing on peripheral venoarterial extracorporeal membrane oxygenation (V-A ECMO) when a low right radial arterial partial pressure of carbon..

Perfusfind S.L.

Abstract Objective Myocardial protection research in adult cardiac surgery has increasingly examined single dose del Nido cardioplegia alongside conventional multidose blood cardioplegia. Using a scientometric modeling approach, this study aims..

Perfusfind S.L.

Abstract Aim Acute kidney injury (AKI) is a major complication of coronary artery bypass grafting (CABG). Existing predictive models show limited accuracy and rarely include modifiable intraoperative risk factors. Therefore,..

Perfusfind S.L.

Abstract Background/Objectives: Volatile anesthetic dosing during cardiopulmonary bypass (CPB) is poorly standardized. We estimated the end-tidal sevoflurane (ETsevo) concentration required to maintain adequate anesthesia during CPB and investigated the effects..

Perfusfind S.L.

Abstract Background Acute myocardial infarction-related cardiogenic shock (AMI-CS) remains associated with extremely high mortality in patients with acute myocardial infarction despite timely revascularization and advances in mechanical circulatory support (MCS)...

Perfusfind S.L.

Abstract Introduction Early detection of acute brain injury (ABI) in patients on venoarterial extracorporeal membrane oxygenation (VA ECMO) is challenging. We aimed to investigate if heart rate variability (HRV) in..

Perfusfind S.L.

Abstract Background/Objectives: Acute kidney injury (AKI) remains a significant complication following cardiac surgery, associated with increased morbidity and mortality. The early detection of AKI is limited by the cost, availability,..

Perfusfind S.L.

Abstract Despite the advances in technology, new patient populations, new medications, and multiple monitoring algorithms for anticoagulation, bleeding, and thrombosis complications remain high among those receiving extracorporeal life support (ECLS)..