Tags Archives: postoperative delirium

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Phase-Specific Electroencephalography Monitoring: A Dynamic Approach to Predict Postoperative Delirium During Aortic Surgery

Abstract Background:  Static or averaged electroencephalography (EEG) metrics may fail to capture dynamic cerebral changes during surgery. We assessed the EEG features during aortic arch surgery with cardiopulmonary bypass (CPB)..

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Excessive Anesthetic Depth Is Associated With Increased Rate of Postoperative Delirium After Cardiac Surgery: A Retrospective Analysis of Processed Electroencephalography

Abstract Objectives To evaluate whether prolonged exposure below a Patient State Index (PSI) threshold of 25—considered indicative of excessive anesthesia depth via processed electroencephalography—is associated with postoperative delirium (POD) in..

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Delirium after Coronary Artery Bypass Grafting: Where We Are Now and Setting Goals for Where We Could Go Next

Abstract Delirium remains a common yet important complication after coronary artery bypass grafting (CABG)., Despite robust research linking delirium to adverse outcomes in this setting, it is still regarded as a..

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Oxygenator-related gaseous microemboli and postoperative delirium after on-pump coronary artery bypass grafting: a prospective cohort study

Abstract Background The increasing preference for off-pump coronary artery bypass grafting (CABG) reflects efforts to reduce complications associated with cardiopulmonary bypass (CPB). A lower incidence of postoperative delirium (POD) after..

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Efficacy of intranasal insulin in reducing the incidence of postoperative delirium: A systematic review and meta-analysis of randomised controlled trials

Abstract Background: Postoperative delirium is a common and serious complication in surgical patients, often leading to prolonged hospitalisation and increased morbidity. Intranasal insulin has shown promising results in preventing postoperative..

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Association of Vitamin C Administration with Postoperative Delirium After Cardiac Surgery with Cardiopulmonary Bypass: A Single-Center Retrospective Exploratory Cohort Study

Abstract Objectives: Oxidative stress after cardiac surgery may disrupt the blood–brain barrier and contribute to postoperative delirium (POD). Although associations between oxidative stress and POD are recognized, whether vitamin C (VC)..

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Delirium after cardiac surgery incidence and perioperative risk factors in a prospective cohort

Abstract Background Delirium is an aetiologically nonspecific cerebral syndrome characterised by disturbances in consciousness, attention, perception, cognition, memory, psychomotor activity, emotion, and the sleep–wake cycle. It frequently occurs after cardiac..

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Perioperative Profiles of Immune Cells in Patients with Postoperative Delirium After Cardiac Surgery with Cardiopulmonary Bypass

Abstract Background: Postoperative delirium (POD) is known to involve systemic inflammatory responses, but the characteristics of the immune cell types involved in these responses are unclear.  Methods: In this prospective study, we..

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Zero-Balance Ultrafiltration Reduces Postoperative Delirium After Cardiac Surgery with Cardiopulmonary Bypass: A Randomized Controlled Trial

Abstract Purpose To assess the effects of conventional ultrafiltration and conventional plus zero-balanced ultrafiltration on delirium and cognition in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods A total..

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A simple ratio, a complex outcome: glucose-to-albumin ratio predicts delirium in ICU patients after cardiac surgery

Abstract Introduction Postoperative delirium (POD) is a frequent and serious complication after cardiac surgery. The glucose-to-albumin ratio (GAR) integrates metabolic and nutritional status, but its predictive value for POD in..

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Early alpha power in the frontal lobe area can predict delirium after cardiac surgery

Abstract Background Delirium is a common postoperative complication in patients undergoing cardiac surgery and is associated with prolonged hospitalization and persistent cognitive impairment. This study aimed to assess the predictive..

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Hemodynamic control during cardiopulmonary bypass and the incidence of postoperative delirium– a post hoc analysis

Abstract Background Delirium is a common neurological complication after cardiac surgery. The purpose of the present study was to analyze the association between hemodynamic fluctuations during cardiopulmonary bypass (CPB) and..

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Intranasal insulin enhances postoperative sleep quality and delirium in middle-aged cardiac surgery patients: A randomized controlled trial

Abstract Background Postoperative delirium (POD) remains a significant complication following cardiopulmonary bypass (CPB) surgery, particularly in middle-aged patients who constitute the majority of this surgical population. While intranasal insulin (INI)..

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Establishment and validation of a nomogram of postoperative delirium in patients undergoing cardiac surgery: a retrospective study of MIMIC-IV

Abstract Objective To establish a nomogram for predicting the occurrence of postoperative delirium (POD) in patients undergoing cardiac surgery. Materials and methods Data from 5379 patients were retrieved from the..

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Practical prognostic tools to predict the risk of postoperative delirium in older patients undergoing cardiac surgery: visual and dynamic nomograms

Abstract Purpose Postoperative Delirium (POD) has an incidence of up to 65% in older patients undergoing cardiac surgery. We aimed to develop two dynamic nomograms to predict the risk of..

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Intra- and early postoperative predictors of delirium risk in cardiac surgery: results from the prospective observational FINDERI study

Abstract Background:  Postoperative delirium (POD) is a severe complication following cardiac surgery and is associated with increased morbidity and mortality. The impact of intra- and early postoperative factors on the..

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Systematic literature review on early detection of postoperative delirium in adult patients after cardiac surgery

Abstract Background Postoperative delirium (POD) is a cognitive decline and attention deficit that can occur in patients after cardiac surgery. Despite extensive research identifying the risk factors, POD often remains..

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Cerebral Overperfusion Despite Reduced Cortical Metabolism Is Associated with Postoperative Delirium in Cardiac Surgery Patients: A Prospective Observational Study

Abstract Background: Decreased cerebral oximetry (rSO2) in cardiac surgery is associated with postoperative delirium (POD). However, interventions optimizing intraoperative rSO2 are inconclusive.    Methods: In this prospective observational cohort study, the..

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Association between baseline serum bicarbonate and the risk of postoperative delirium in patients undergoing cardiac surgery in the ICU: a…

Abstract Background Although serum bicarbonate is a reliable predictor of various disease complications, its relationship with postoperative delirium (POD) remains unclear. Our research aimed to assess the effect of baseline..

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Effect of mannitol on postoperative delirium in patients undergoing coronary artery bypass graft: a randomised controlled trial

Abstract Objective Postoperative delirium (POD), especially after cardiac surgery with cardiopulmonary bypass (CPB), is a relatively common and severe complication increasing side effects, length of hospital stay, mortality and healthcare resource..

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The association between cerebral blood flow variations during on-pump coronary artery bypass grafting surgery and postoperative delirium

Abstract Introduction Postoperative delirium (POD) has a major impact on patient recovery after cardiac surgery. Although its pathophysiology remains unclear, there could be a correlation between cerebral blood flow (CBF)..

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Intraoperative Blood Pressure Management and Its Effects on Postoperative Delirium After Cardiac Surgery: A Single-Center Retrospective Cohort Study

Abstract Objectives There is accumulating evidence that blood pressure management might be associated with end-organ dysfunction after cardiac surgery. This study aimed to investigate the impact of intraoperative hypotension (IOH)..

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Target flow deviations on the cardiopulmonary bypass cause postoperative delirium in cardiothoracic surgery—a retrospective study evaluating temporal fluctuations of perfusion…

Abstract OBJECTIVES Postoperative delirium (POD) is common, costly and associated with long-term morbidity and increased mortality. We conducted a cohort study to assess the contribution of cardiopulmonary bypass (CPB) to..

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Risk factors and incidence of postoperative delirium after cardiac surgery in children: a systematic review and meta-analysis

Abstract Delirium, a form of acute cerebral dysfunction, is a common complication of postoperative cardiac surgery in children. It is strongly associated with adverse outcomes, including prolonged hospitalization, increased mortality,..

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Serum neurofilament light and postoperative delirium in cardiac surgery: a preplanned secondary analysis of a prospective observational study

Abstract Background Impaired cognition is a major predisposing factor for postoperative delirium but it is not systematically assessed. Anesthesia and surgery may cause postoperative delirium by affecting brain integrity. Neurofilament..

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Online interpretable dynamic prediction models for postoperative delirium after cardiac surgery under cardiopulmonary bypass developed based on machine learning algorithms:…

Abstract Objective: Postoperative delirium (POD) is strongly associated with poor early and long-term prognosis in cardiac surgery patients with cardiopulmonary bypass (CPB). This study aimed to develop dynamic prediction models for..

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Is a hyperosmolar pump prime for cardiopulmonary bypass a risk factor for postoperative delirium? A double blinded randomised controlled trial

Abstract Objective:  Postoperative delirium (POD) is common after cardiac surgery. We have previously identified plasma sodium concentration and the volume of infused fluids during surgery as possible risk factors. Both..

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Timing, Threshold, and Duration of Intraoperative Hypotension in Cardiac Surgery: Their Associations With Postoperative Delirium

Abstract Objectives To study the timing, threshold, and duration of intraoperative hypotension (IOH) associated with the risk of  (POD). Design A single-center retrospective observational study. Setting University teaching hospital. Participants A..

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Prediction of Postoperative Delirium After Cardiac Surgery with A Quick Test of Cognitive Speed, Mini-Mental State Examination and Hospital Anxiety…

Abstract Purpose: To evaluate if preoperative assessment with A Quick Test of Cognitive Speed (AQT) could increase the accuracy of predicting delirium after cardiac surgery compared to Mini-Mental State Examination (MMSE),..

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Postoperative delirium prediction using machine learning models and preoperative electronic health record data

Abstract Background Accurate, pragmatic risk stratification for postoperative delirium (POD) is necessary to target preventative resources toward high-risk patients. Machine learning (ML) offers a novel approach to leveraging electronic health..

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