Tags Archives: Ecmo paediatric

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A Comparative Analysis of Bivalirudin and Heparin for Extracorporeal Membrane Oxygenation in a Pediatric Cardiothoracic Intensive Care Unit

Abstract Unfractionated heparin has long been the conventional anticoagulant for pediatric mechanical circulatory support (MCS). As bivalirudin has gained traction in ventricular assist devices (VAD) management, its role in extracorporeal..

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Functional Status Change in Pediatric Extracorporeal Membrane Oxygenation Survivors is Equivalent to Propensity-Matched Patients Managed Without Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is now commonly used to manage refractory pediatric cardiac or respiratory failure. Traditionally, ECMO has been associated with high morbidity. However, despite advancements in ECMO..

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Experience With Pediatric Extracorporeal Membrane Oxygenation (ECMO) Standby at Two High-Volume Centers

Abstract Extracorporeal membrane oxygenation (ECMO) can provide an option for high-risk procedures that may result in cardiopulmonary collapse. The indications for ECMO standby are not well delineated. We describe the..

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Thromboelastography in Children Undergoing Extracorporeal Membrane Oxygenation

Abstract Background Children undergoing extracorporeal membrane oxygenation (ECMO) are at risk of hematologic and coagulation complications, including intracranial hemorrhage. Thromboelastography is used to monitor anticoagulation in patients receiving ECMO, but..

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Arterial Changes After Vascular Reconstruction Following Decannulation From Extracorporeal Life Support: Single-Center, Retrospective Cohort 2002–2022

Abstract Objectives:  Decannulation after pediatric extracorporeal life support (ECLS) may be accompanied by arterial reconstruction. There is a paucity of data on arterial morphology following reconstruction. We sought to characterize..

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Multisite Venovenous Extracorporeal Membrane Oxygenation in Pediatric Patients Under 15 kg: Three-Center, Analysis of Surgical Versus Percutaneous Approach and Thrombosis…

Abstract Objectives:  An increasing number of pediatric centers use the femoral vein in neonates and smaller children to provide venovenous multisite (VVMS) extracorporeal membrane oxygenation (ECMO), but there are no..

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A scoping review: Point-of-care ultrasound (POCUS) use in paediatric ECMO

Abstract Objective This scoping review aimed to examine current literature on the use of point-of-care ultrasound (POCUS) in paediatric patients supported by extracorporeal membrane oxygenation (ECMO). It assessed existing evidence,..

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Over 30 Years of Neonatal Respiratory Extracorporeal Membrane Oxygenation From a Regional Program

Abstract This referral center’s prospective inception-cohort study from 1989 to 2000 (Era 1) and 2000 to 2022 (Era 2) included 232 consecutive children having neonatal respiratory extracorporeal membrane oxygenation (ECMO)...

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Outcomes in early term neonates requiring extracorporeal membrane oxygenation

Abstract Objectives To evaluate ECMO-related morbidity and mortality between Early-term (ET) and Full-term (FT) infants. Methods We performed a retrospective review of 3,831 neonatal ECMO runs for meconium aspiration syndrome..

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Multisite Venovenous Extracorporeal Membrane Oxygenation in Pediatric Patients Under 15 kg: Three-Center, Analysis of Surgical Versus Percutaneous Approach and Thrombosis…

Abstract Objectives:  An increasing number of pediatric centers use the femoral vein in neonates and smaller children to provide venovenous multisite (VVMS) extracorporeal membrane oxygenation (ECMO), but there are no..

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Advances and Challenges in Artificial Womb for Respiratory Support in Extremely Low Gestational Age Neonates: A Narrative Review

Abstract Background Respiratory management of extremely low gestational age neonates (ELGANs) is a major challenge in neonatal intensive care, as they face high mortality and morbidity due to complications such..

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Mobile ECMO for inter-hospital transport of pediatric patients: experience from 22 cases

Abstract Objective To summarize the management experience of inter-hospital transport of critically ill children with extracorporeal membrane oxygenation (ECMO) in our hospital and provide evidence for the mobile ECMO for..

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Evaluation of the impact of extracorporeal membrane oxygenation (ECMO) oxygenator shunt flow on neonatal hemolysis: An in vitro study

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) is utilized in critically ill neonates with severe cardiopulmonary failure. Hemolysis is a potential complication and is associated with significantly increased morbidity and mortality...

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VV ECMO cannulation in infants and children under 10 kg: Evolving strategies, outcomes, and innovations

Abstract Venovenous extracorporeal membrane oxygenation (VV ECMO) has become an increasingly preferred modality for respiratory support in neonates and infants under 10 kg, driven by a growing recognition of its..

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Outcomes of a Second Run of Extracorporeal Membrane Oxygenation in Neonates: A Propensity Score Matched Analysis of a Nationwide Registry

Abstract This study analyzed the outcomes of neonates undergoing a second run of extracorporeal membrane oxygenation (ECMO) to determine whether there is a benefit to a repeated run. We used..

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Repeated Treatments With Extracorporeal Membrane Oxygenation in Congenital Diaphragmatic Hernia Patients: A Registry Analysis

Abstract Congenital diaphragmatic hernia (CDH) is a rare and severe malformation that can lead to life-threatening postnatal physiological challenges which may require lifesaving extracorporeal membrane oxygenation (ECMO) support, sometimes more..

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“When I walk away and wonder, did I make the best decision?”: A decisional needs assessment among providers involved in…

Abstract Purpose Extracorporeal cardiopulmonary resuscitation (ECPR) is an advanced resuscitation therapy for cardiopulmonary arrest refractory to standard CPR. ECPR treatment recommendations are not supported by strong evidence, and institutional criteria..

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Inflammatory Markers During Extracorporeal Membrane Oxygenation in Neonates With Congenital Diaphragmatic Hernia

Abstract This study aimed to assess whether the proinflammatory markers procalcitonin (PCT), C-reactive protein (CRP), or interleukin 6 (IL-6) are associated with mortality in neonates with congenital diaphragmatic hernia (CDH)..

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Temporal trends and risk factors for bleeding and thrombosis in pediatric ECMO: A multicenter cohort study

Abstract Introduction Bleeding and thrombosis are major causes of morbidity and mortality in pediatric extracorporeal membrane oxygenation (ECMO), yet their evolving, time-dependent risks remain poorly defined. This study evaluated clinical..

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Large Single-Center Experience With Extubation During Neonatal and Pediatric Extracorporeal Membrane Oxygenation

Abstract Extubation of select neonatal and pediatric patients supported with extracorporeal membrane oxygenation (ECMO) may avoid ventilator-induced lung injury, decrease neurosedative exposure, and improve rehabilitation. A single-center retrospective cohort study..

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Pulmonary arterial hypertension in neonates and children post open-heart surgery: assessment and management including extracorporeal membrane oxygenation (ECMO) — a…

Abstract Background Congenital heart disease (CHD) that requires heart surgery is common. Severe postoperative pulmonary hypertension (PH) occurs in 2% of cardiac procedures and is associated with high morbidity and..

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Arterial Cannula Size Selection for Percutaneous Femoral Venoarterial Extracorporeal Membrane Oxygenation in Children and Young Adults: Solving a Goldilocks Paradox?

Abstract The correct arterial cannula size for percutaneous femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO) cannulation is imperative for adequate circulatory support. We aimed to describe the relationship between cannula size,..

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The Relationship Between the Type of Microorganisms Isolated in Cultures and Outcomes in Children on Extracorporeal Membrane Oxygenation Support Following…

Abstract Objetives Extracorporeal membrane oxygenation (ECMO) after surgery for congenital heart disease (CHD) provides hemodynamic support to patients when their myocardial function is temporarily affected. Postoperative infections in children with..

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Investigation of contamination and environmental exposure of cold/heated water supply systems for extracorporeal circulation used in ECMO and other applications

Abstract Infection cases have been reported where Legionella spp. and NTM (non-tuberculous mycobacteria) increased due to the contamination of circulating water in cold/heated water supply systems for extracorporeal circulation used in cardiac..

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Refractory anaphylactic shock to peanut ingestion in a pediatric patient requiring extracorporeal life support

Abstract Introduction Current guidelines advise that anaphylactic shock refractory to traditional treatments may be managed with extracorporeal life support (ECLS), but reports have been exclusive to adults. Case Report We..

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Is hyperoxia in early pediatric veno-veno extracorporeal life support associated with mortality?

Abstract Background: Data is limited regarding the effects of supraphysiologic blood oxygen tension (hyperoxia) in patients requiring extracorporeal life support (ECLS). We sought to evaluate the association between hyperoxia and..

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Comprehensive secondary analysis of thrombotic events in pediatric patients receiving extracorporeal membrane oxygenation: A prospective cohort study

Abstract Introduction This study aims to describe laboratory and clinical factors associated with thrombotic events during prolonged pediatric extracorporeal membrane oxygenation. Methods A secondary analysis of a multi-center prospective study..

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Evaluation of Intraoperative Bivalirudin Anticoagulation in Neonates and Infants Undergoing Arterial Switch Operation on Integrated ECMO-CPB Circuit: A Prospective Study

Abstract Objectives To ascertain the dosage of bivalirudin in neonates and infants undergoing arterial switch operation on integrated extracorporeal membrane oxygenation–cardiopulmonary bypass (CPB) circuit. Design Pilot study. Setting A tertiary..

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Hyperlactatemia in Critically Ill Children: Modeling Early Recovery Kinetics After Initiation of Extracorporeal Membrane Oxygenation

Abstract Objectives:  Blood lactate concentration ([Lac]b) reflects the balance among production, clearance (Cl[Lac]), and volume of distribution. We have observed dramatic improvement in [Lac]b in critically ill patients after starting support..

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Assembling, Priming, and Storing Circuits for Pediatric and Neonatal Extracorporeal Membrane Oxygenation

Abstract The storing of dry-assembled and primed extracorporeal membrane oxygenation (ECMO) circuits is common practice and endorsed by the Extracorporeal Life Support Organization (ELSO) for up to 30 days. We..

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