Abstract Introduction Brain infarction (BI) is a severe complication of extracorporeal membrane oxygenation (ECMO) with high morbidity and mortality. We aimed to determine the incidence of BI and identify predictors..
Read MoreAbstract Objectives The objective of this survey is to assess current practices in anticoagulation management, laboratory monitoring, and hematology involvement in extracorporeal membrane oxygenation (ECMO) patients. Methods A cross-sectional international..
Read MoreAbstract Background: Hyperoxia induces oxidative stress and can exacerbate inflammatory response to Veno-Arterial Extracorporeal Life Support (VA–ECLS). This study aimed to evaluate the association between hyperoxia during VA–ECLS and morbidity, complications,..
Read MoreAbstract Background: Extracorporeal membrane oxygenation (ECMO) in pediatric patients requires monitoring by specialists to optimize outcomes. Practice variability exists among pediatric ECMO centers across the country. We present a bedside..
Read MoreAbstract Objectives: The parenteral anticoagulant bivalirudin has favorable safety and efficacy outcomes compared with unfractionated heparin (UFH) in pediatric patients requiring extracorporeal membrane oxygenation (ECMO), and is frequently monitored using..
Read MoreAbstract Background Extracorporeal membrane oxygenation (ECMO) is a critical support modality for patients with reversible cardiopulmonary failure. Despite its benefits, ECMO is associated with neurologic adverse events (NAE), including seizures..
Read MoreAbstract Introduction Extracorporeal membrane oxygenation (ECMO) provides life-saving support for patients with advanced cardiorespiratory failure, yet unanticipated difficulties with peripheral cannulation can delay therapy. This study describes challenging neonatal and..
Read MoreAbstract Objectives: To test the feasibility and safety of a randomized controlled trial (RCT) delivering nitric oxide into the sweep gas of extracorporeal membrane oxygenation (ECMO) circuits (sNO) in critically..
Read MoreAbstract Objectives To develop a multimodal pediatric critical care datamart supporting predictive modeling and decision support tool development, integrating high-resolution physiologic and clinical data and future clinical deployment. Materials and..
Read MoreAbstract Background/Objectives: Venovenous extracorporeal membrane oxygenation (VV ECMO) supports reversible respiratory failure when mechanical ventilation fails. Technological advances and specialized teams now enable ECMO initiation at referring centers, even for high-risk..
Read MoreAbstract The last 10 years have seen an exponential rise in the use of extracorporeal life support (ECLS), also frequently referred to as ECMO (extracorporeal membrane oxygenation) when a membrane..
Read MoreAbstract The 19th International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion took place on May 16 and 17, 2025, at the InRad Events Center of the..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) has been used since 1975 to provide temporary cardiorespiratory support in neonates, children, and adults with severe cardiopulmonary conditions unresponsive to conventional therapy. Initially focused..
Read MoreAbstract Introduction Due to anticoagulation during Extracorporeal Membrane Oxygenation (ECMO), patients face a higher risk of bleeding. This study aimed to assess the correlation between anticoagulation assays and hemorrhage in..
Read MoreAbstract Objective: Unfractionated heparin (UFH) is the most widely used anticoagulant during extracorporeal membrane oxygenation (ECMO). Optimal dosing of UFH for children undergoing ECMO is unknown, leading to suboptimal exposure...
Read MoreAbstract Objective We test the hypothesis that pediatric arterial (“peds art”) cannulae as distal perfusion catheters (DPCs) for venoarterial extracorporeal membrane oxygenation provide more favorable distal limb hemodynamics than introducer..
Read MoreAbstract Objectives: To identify factors associated with the development of death by neurologic criteria (DNC) in neonates treated with extracorporeal membrane oxygenation (ECMO). Design: Retrospective registry study. Setting: Data reported..
Read MoreAbstract Objective: To describe those neonates with dextro-transposition of the great arteries (d-TGA) who undergo preoperative support with extracorporeal membrane oxygenation (ECMO) and to compare outcomes in those undergoing the..
Read MoreAbstract (ECMO) is an invaluable resource in the treatment of critically ill children with cardiopulmonary failure. To date, over 36,000 children have been placed on ECMO and the utilization of..
Read MoreAbstract Objectives: Extracorporeal membrane oxygenation (ECMO) plays a crucial role in the outcome of children following surgery for congenital heart disease. However, its availability and affordability are minimal across the globe...
Read MoreAbstract Background Peripheral veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) cannulation in children poses a significant clinical challenge due to wide variations in body size, vessel caliber, and risk profiles. Purpose..
Read MoreAbstract Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and cardiopulmonary bypass (CPB) are used during pediatric heart surgery to provide cardiopulmonary support to patients as they undergo and recover from surgical..
Read MoreAbstract Unfractionated heparin has long been the conventional anticoagulant for pediatric mechanical circulatory support (MCS). As bivalirudin has gained traction in ventricular assist devices (VAD) management, its role in extracorporeal..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is now commonly used to manage refractory pediatric cardiac or respiratory failure. Traditionally, ECMO has been associated with high morbidity. However, despite advancements in ECMO..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) can provide an option for high-risk procedures that may result in cardiopulmonary collapse. The indications for ECMO standby are not well delineated. We describe the..
Read MoreAbstract Background Children undergoing extracorporeal membrane oxygenation (ECMO) are at risk of hematologic and coagulation complications, including intracranial hemorrhage. Thromboelastography is used to monitor anticoagulation in patients receiving ECMO, but..
Read MoreAbstract Objectives: Decannulation after pediatric extracorporeal life support (ECLS) may be accompanied by arterial reconstruction. There is a paucity of data on arterial morphology following reconstruction. We sought to characterize..
Read MoreAbstract Objectives: An increasing number of pediatric centers use the femoral vein in neonates and smaller children to provide venovenous multisite (VVMS) extracorporeal membrane oxygenation (ECMO), but there are no..
Read MoreAbstract Objective This scoping review aimed to examine current literature on the use of point-of-care ultrasound (POCUS) in paediatric patients supported by extracorporeal membrane oxygenation (ECMO). It assessed existing evidence,..
Read MoreAbstract This referral center’s prospective inception-cohort study from 1989 to 2000 (Era 1) and 2000 to 2022 (Era 2) included 232 consecutive children having neonatal respiratory extracorporeal membrane oxygenation (ECMO)...
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