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Intraoperative blood recovery in cancer surgery: A pilot study evaluating local feasibility

Abstract Background Cancer surgery patients are among those most at high risk of perioperative anemia. Allogeneic transfusions are linked to adverse effects, including increased cancer recurrence and mortality. Intraoperative cell..

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Effects of inhaled anaesthetic agents on the oxygen dissociation curve: An updated discussion

Abstract The oxygen dissociation curve is a critical concept in understanding how oxygen is transported in the blood and delivered to tissues. In anaesthesia, inhaled anaesthetic agents are the fundamental..

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Prevalence and impact of ECMO cannula colonization: a single center study

Abstract During ECMO therapy, infections are common and have substantial impact on treatment outcomes. However, data on the prevalence and clinical impact of microbial ECMO cannula colonization are scarce. Between..

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Electroencephalogram monitoring during anesthesia and critical care: a guide for the clinician

Abstract Perioperative anesthetic, surgical and critical careinterventions can affect brain physiology and overall brain health. The clinical utility of electroencephalogram (EEG) monitoring in anesthesia and intensive care settings is multifaceted,..

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Bleeding Definitions in Pediatric Extracorporeal Membrane Oxygenation (ECMO) Studies: A Systematic Review and Meta-Analysis

Abstract Extracorporeal membrane oxygenation (ECMO) supports severe cardiorespiratory failure but carries a significant bleeding risk. This systematic review aims to report bleeding definitions in studies involving neonates and children treated..

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Impact of a Generated Magnetic Field at the Schumann Resonance Frequency on Skin Blood Perfusion and Peripheral Pulse Amplitudes

Abstract A pilot study was conducted in six young adult male volunteers (25.8±1.3 years) to determine if there was evidence of an effect of a locally applied magnetic field at..

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Venoarterial Extracorporeal Membrane Oxygenation: A Better Pressor

Abstract PROFOUND HYPOTENSION AND end-organ hypoperfusion are most often the consequence of inadequate systemic blood flow from primary cardiac failure (cardiogenic shock) or hemorrhage (hemorrhagic shock). However, profound hypotension may..

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Clinical assessment of cannula performance during adult minimally invasive valve surgery using predictive mathematical models

Abstract OBJECTIVES Peripheral cannula selection in minimally invasive cardiac surgery (MICS) is crucial, as venous drainage limitations during cardiopulmonary bypass (CPB can impair end-organ perfusion and overall outcomes. This study..

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Extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest

Abstract When conventional cardiopulmonary resuscitation (CCPR) cannot restore spontaneous circulation, the initiation of venoarterial extracorporeal membrane oxygenation during refractory cardiac arrest—known as extracorporeal CPR (ECPR)—might restore circulation and adequate tissue..

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Extracorporeal membrane oxygenation for systemic lupus erythematosus: An ELSO registry analysis

Abstract The success of extracorporeal membrane oxygenation (ECMO) in treating Systemic Lupus Erythematosus (SLE) and the risk factors associated with mortality remain uncertain.   Methods: We describe the survival outcomes at..

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Extracorporeal Membrane Oxygenation Cannulation Site Affects Coronary and Cerebral Perfusion When Combined With Intra-Aortic Balloon Pump

Abstract The use of intra-aortic balloon pump (IABP) alongside venoarterial extracorporeal membrane oxygenation (VA-ECMO) in critically ill patients presenting refractory cardiogenic shock raises questions regarding its impact on organs perfusion...

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A Comprehensive Review of Left Atrial Venoarterial Extracorporeal Membrane Oxygenation

Abstract Cardiogenic shock (CS) in patients with structural heart disease (SHD) and severe valvular abnormalities poses unique challenges to traditional mechanical circulatory support (MCS) strategies, such as intra-aortic balloon pumps..

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Bullying, Harassment, and Undermining Behavior in Cardiothoracic Surgery in the United Kingdom and Ireland

Abstract Background Bullying, harassment, and undermining behavior has a profound detrimental effect on the multiprofessional team, patient safety, and clinical outcomes. Bullying creates a poor working and training environment, increasing..

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Neuron-Specific Enolase and S100B as Biomarkers of Ischemic Brain Injury During Surgery

Abstract Biochemical markers can be used in addition to neuroimaging techniques to evaluate the extent of ischemic brain injuries and to enable earlier diagnosis and faster intervention following the ischemic..

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Factors Influencing Recirculation in Veno-Venous Extracorporeal Membrane Oxygenation: Insights From a Controlled Bench Study

Abstract This study investigated factors influencing recirculation in veno-venous extracorporeal membrane oxygenation (VV ECMO) using a controlled bench model comprising a VV ECMO circuit and a mock circulatory loop with..

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State-of-the-Art Review: Advantages and Disadvantages of Femoral Versus Central Cannulation

Abstract The choice of cannulation technique for cardiopulmonary bypass remains a critical decision in cardiac surgery with direct consequences for intraoperative management and patient outcomes. Central and femoral cannulation represent..

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Probiotic mitigates gut hypoperfusion-associated acute gastrointestinal injury in patients undergoing cardiopulmonary bypass: a randomized controlled trial

Abstract Background Acute gastrointestinal injury (AGI) after cardiopulmonary bypass (CPB) is associated with poor prognosis. This study aimed to evaluate the effect of preoperative probiotic supplementation on the incidence of..

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Fine-Mapping the Association of Acute Kidney Injury With Mean Arterial and Central Venous Pressures During Coronary Artery Bypass Surgery

Abstract BACKGROUND:  Prior studies identified thresholds for mean arterial pressure (MAP <65 mm Hg) and central venous pressure (CVP >12 mm Hg) beyond which risk for cardiac surgery-associated acute kidney..

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Near-infrared spectroscopy to monitor cerebral and renal oxygen saturation during cardiopulmonary bypass surgery for paediatric congenital heart disease: study protocol…

Abstract Background Current indicators for monitoring intraoperative organ function remain predominantly indirect, delayed and non-specific, particularly in paediatric populations undergoing congenital heart surgery, where multifactorial influences further complicate functional assessments. Emerging..

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Association of early perioperative stroke after cardiothoracic surgery with intraoperative regional cerebral oxygenation using near-infrared spectroscopy: an observational cohort study…

Abstract Purpose Patients undergoing cardiothoracic surgery are at risk of developing perioperative stroke, but residual effects of anesthesia may hamper timely detection. This study aims to determine if there is..

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Maintaining ventilation with very low tidal volume and positive-end expiratory pressure versus no ventilation during cardiopulmonary bypass for cardiac surgery…

Abstract Purpose Cardiopulmonary bypass (CPB) during cardiac surgery mechanically circulates and oxygenates the blood, bypassing the heart and lungs. Despite limited evidence, maintaining mechanical ventilation (MV) during CPB is recommended,..

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Long-Term Functional Outcomes in the First 12 Months After VA-ECMO in Adult Patients: A Prospective, Multicenter Study

Abstract BACKGROUND: Long-term outcomes and quality of life have been identified as core patient-centered outcomes for venoarterial extracorporeal membrane oxygenation (VA-ECMO) research. The aim of this study is to investigate..

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Infectious diseases and infection control prevention strategies in adult and pediatric population on ECMO

Abstract As survival after ECMO improves and use of ECMO support increases in both pediatric and adult population, there is a need to focus on both the morbidities and complications..

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Pre-hospital ECPR for Refractory Cardiac Arrest – The PRECARE pilot feasibility study

Abstract Background Survival from refractory out of hospital cardiac arrest (OHCA) treated with conventional cardiopulmonary resuscitation (CCPR) remains low. Extracorporeal cardiac resuscitation (ECPR) is increasingly be utilised in refractory OHCA,..

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Thrombus Migration Resulting From Cessation of Cardiopulmonary Bypass Flow in a Patient With Left Ventricular Thrombus

Introduction Left ventricular (LV) thrombus formation is a known complication associated with acute myocardial infarction and other conditions that impair LV function, carrying a risk for systemic embolization., In this report,..

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A robust analysis of alternate methods for estimating blood volume

Abstract Aim This study evaluates the accuracy of a newly derived blood volume estimation formula based on the Boer equation for lean body mass, comparing its performance against the Nadler,..

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Factors Affecting the Time to Postoperative Recovery of Consciousness in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass: A Retrospective Study

Abstract Introduction: The causes of delayed recovery of consciousness from anesthesia after cardiac surgery with cardiopulmonary bypass are diverse and often related to multiple factors. This study investigated the factors..

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Impact of Point-of-care allogeneic red blood cell washing on markers of transfusion-related respiratory complications: A phase II randomized clinical trial

Abstract Background:  Transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO) are leading causes of transfusion-related morbidity and mortality. Soluble factors in red blood cell (RBC) supernatant may increase..

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Comparison of Three Mathematical Models of the Pharmacokinetics of Heparin to Guide the Use of Protamine in a Large Simulated…

Abstract Background: In cardiac surgery, protamine is used to reverse the effects of heparin after separation from cardiopulmonary bypass (CPB). Excess of protamine has been demonstrated to cause platelet dysfunction and..

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The impact of arterial cannulation strategy on carotid perfusion during cardiopulmonary bypass: A computational fluid dynamics analysis from the perspective…

Abstract Introduction: Cardiopulmonary bypass (CPB) is utilized during cardiovascular surgery to maintain organ oxygen supply and blood perfusion instead of cardiopulmonary function. Three primary methods of artery cannulation used for CPB..

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