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Recombinant Factor VIIa Versus Prothrombin Complex Concentrate in Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-analysis

Abstract Perioperative hemorrhage during cardiac surgery is a frequent occurrence and can result in significant morbidity and mortality for patients. Prothrombin complex concentrate (PCC) and recombinant factor VIIa (rFVIIa) are..

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Early Exposure to Arterial Hyperoxia During Extracorporeal Membrane Oxygenator Support and Acute Brain Injury and Mortality in Patients With Cardiogenic…

Abstract BACKGROUND:  Patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) are frequently managed with varying degrees of hyperoxia. Existing data suggest that higher levels of Pao2 correlate with worsened outcome in patients..

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“Safety of ECMO Cannulation: Organization and Standardized Training Matters”

Abstract We appreciate the insightful remarks by Sin et al regarding our systematic review and meta-analysis on extracorporeal membrane oxygenation (ECMO) cannulation by intensivists. Their comments highlight important considerations for..

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A simple ratio, a complex outcome: glucose-to-albumin ratio predicts delirium in ICU patients after cardiac surgery

Abstract Introduction Postoperative delirium (POD) is a frequent and serious complication after cardiac surgery. The glucose-to-albumin ratio (GAR) integrates metabolic and nutritional status, but its predictive value for POD in..

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Simultaneous coronary artery bypass grafting and transcarotid transcatheter aortic valve implantation using a cardiopulmonary bypass-assisted carotid perfusion

Abstract Managing severe  (AS) alongside complex  (CAD) in frail patients is challenging. A 79-year-old female with resting dyspnea was diagnosed with severe AS and CAD. While  (CABG) was the appropriate treatment for CAD,..

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Novel use of negative pressure ventilation for weaning of venovenous extracorporeal membrane oxygenation

Abstract Negative pressure ventilation (NPV) has been used to assist patients with respiratory failure. Venovenous extracorporeal membrane oxygenation (V-V ECMO) supports patients with acute lung injury who do not respond..

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Efficacy and safety of tranexamic acid in cardiac surgery: a systematic review and network meta-analysis

Abstract Background Tranexamic acid (TXA) is recommended for reducing blood loss and transfusion in cardiac surgery. However, there are concerns regarding the safety profile of TXA, especially its proconvulsant effects...

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Death and new disability following bleeding complications during venoarterial extracorporeal membrane oxygenation. A prospective cohort study from the EXCEL registry

Abstract Introduction Bleeding events are common during the provision of Venoarterial ECMO (VA ECMO). Previous observational has suggested that these bleeding events are associated with an increased risk of in-hospital..

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Indications and outcomes of extracorporeal life support in trauma patients

Abstract BACKGROUND  The use of extracorporeal life support (ECLS) in the trauma population remains controversial and has been reported only in small cohort studies. Recent ECLS technical advances have increased..

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Cardiac surgery in older adults: a retrospective cohort study of outcomes and risk score performance in octogenarians versus patients aged…

Abstract Background The role of cardiac surgery in octogenarians is debated, but limited data exist for patients aged 65–79. This study compared clinical characteristics, surgical procedures, and outcomes between patients ≥ 80..

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Acid-Base Disturbances After Cardiac Surgery: A Cohort Study Using the Physicochemical Approach

Abstract Objective Metabolic acidosis is a common complication following cardiac surgery with cardiopulmonary bypass (CPB). Recent evidence suggests that unmeasured anions (UAs), assessed via the strong ion gap (SIG), may..

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Outcomes in early term neonates requiring extracorporeal membrane oxygenation

Abstract Objectives To evaluate ECMO-related morbidity and mortality between Early-term (ET) and Full-term (FT) infants. Methods We performed a retrospective review of 3,831 neonatal ECMO runs for meconium aspiration syndrome..

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The Impact of Venovenous Extracorporeal Membrane Oxygenation Cannulation Configuration on Hemodynamic Characteristics and Risks of Hemolysis

Abstract Objective To investigate the impact of veno-venous extracorporeal membrane oxygenation (VV-ECMO) cannula configuration and ECMO blood flow on intravascular hemodynamic environment, oxygen saturation, hemolysis, and thrombotic risk under varying..

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Activated Clotting Time Measurement in Cardiac Surgery: An Infinite Game

Abstract To prevent uncontrolled activation of the hemostatic system and thrombin formation that could be triggered by cardiopulmonary bypass (CPB), unfractionated heparin (hereinafter heparin) is administered to induce profound anticoagulation. Effective..

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Frailty changes after cardiac surgery: better or worse?

Abstract Aims Cardiac surgery, as an intervention to repair cardiac pathology, may improve frailty, but the evidence is limited. This secondary analysis explored changes in frailty before and 6 months..

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EACTS Expert Consensus Document on protected cardiac surgery: pre-emptive use of temporary mechanical circulatory support in adult cardiac surgery patients…

Abstract Perioperative low cardiac output syndrome (LCOS) remains a significant complication in adult cardiac surgery, contributing to substantial morbidity, prolonged intensive care, and increased mortality. Its incidence is expected to..

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The impact of pulsatile vs. non-pulsatile perfusion in patients undergoing cardiopulmonary bypass: A comprehensive systematic review and meta-analysis of 33…

Abstract Background Pulsatile perfusion is a developing technique that attempts to mimic the natural pulsatile flow of blood during cardiopulmonary bypass (CBP). Purpose This systematic review and meta-analysis was conducted..

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EuroPerfusion 2026 - Oct 30/31

  Sava Center, Milentija Popovica 9, Belgrado, Beograd, RS, 11070 Main Congress Hall

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Extracorporeal cardiopulmonary resuscitation versus conventional CPR in cardiac arrest: an updated meta-analysis and trial sequential analysis

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) may reduce mortality and improve neurological outcomes in patients with cardiac arrest. We updated our existing meta-analysis and trial sequential analysis to further evaluate..

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Does cannulation site affect outcomes of antegrade cerebral perfusion in aortic arch surgery? A meta-analysis of axillary versus innominate access

Abstract Background The optimal arterial cannulation strategy for establishing antegrade cerebral perfusion during aortic arch surgery remains a subject of ongoing debate. Our meta-analysis compares outcomes between axillary artery (AxA)..

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Between Hope and Harm: A Meta-Synthesis of Family Decision-Making Agonies in ECMO Initiation Crossroads

Abstract Background Family members making decisions about ECMO initiation face high-stakes uncertainty, emotional stress and cultural–ethical dilemmas. However, existing research lacks a synthesised understanding of these decision-making experiences across contexts...

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European Resuscitation Council Guidelines 2025 Special Circumstances in Resuscitation

Abstract These European Resuscitation Council (ERC) Guidelines 2025 on Special Circumstances in Resuscitation are based on the 2025 Consensus on Science with Treatment Recommendations (CoSTR) of the International Liaison Committee..

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Evaluation of Knowledge, Attitudes, and Experiences of Perfusionists on the Safety of Cardiopulmonary Perfusion

Abstract Introduction Perfusion accidents still threaten the safety of perfusion during open-heart surgery. To prevent these accidents and increase perfusion safety, it is important to first determine the profile of..

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Shaping the Future of Partial Heart Transplantation: Innovations and Emerging Applications

Abstract Introduction Partial heart transplantation (PHT) represents a novel and adaptable approach to cardiac surgery, allowing for patient-specific and disease-specific interventions while expanding the donor pool and improving organ stewardship...

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Ethical Dilemmas Surrounding ECMO Withdrawal: A Qualitative Empirical Study

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a critical, life-sustaining intervention often described as ‘a bridge to nowhere’ due to its transient nature and the ethical complexities it entails. This..

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Effect of intraoperative cell salvage on postoperative blood transfusion demand outcomes in cesarean section with placenta previa: a retrospective study…

Abstract Background This study aimed to analyze the postoperative blood transfusion demand and safety of intraoperative cell salvage (ICS) without leukocyte depletion filters in cesarean sections complicated by placenta previa...

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Propofol-supplemented cardioplegia: A multicenter blinded 3-group randomized trial (Propofol for Myocardial Protection Trial 2: ProMPT2)

Abstract Objective: Coronary artery bypass grafting using cardiopulmonary bypass and cardioplegic arrest is an effective treatment for coronary artery disease. Research suggests supplementing the cardioplegia solution with propofol may be..

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Does Autologous Platelet-Rich Plasma Improve Blood Conservation and Postoperative Outcomes in Acute Type A Aortic Dissection Surgery? A Systematic Review…

Abstract Objectives To evaluate whether autologous platelet-rich plasma (aPRP) improves blood conservation and postoperative outcomes in emergency surgery for acute type A aortic dissection (ATAAD). Design Systematic review and meta-analysis..

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Prognostic value of venous-to-arterial pCO2 gap during cardiopulmonary bypass for predicting cardiac surgery-associated kidney injury: A bicentric retrospective study

Abstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is one of the most frequent and severe complications after cardiac surgery. The association between acute kidney injury and the mismatch between..

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