Abstract Perioperative hemorrhage during cardiac surgery is a frequent occurrence and can result in significant morbidity and mortality for patients. Prothrombin complex concentrate (PCC) and recombinant factor VIIa (rFVIIa) are..
Read MoreAbstract BACKGROUND: Patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) are frequently managed with varying degrees of hyperoxia. Existing data suggest that higher levels of Pao2 correlate with worsened outcome in patients..
Read MoreAbstract We appreciate the insightful remarks by Sin et al regarding our systematic review and meta-analysis on extracorporeal membrane oxygenation (ECMO) cannulation by intensivists. Their comments highlight important considerations for..
Read MoreAbstract Introduction Postoperative delirium (POD) is a frequent and serious complication after cardiac surgery. The glucose-to-albumin ratio (GAR) integrates metabolic and nutritional status, but its predictive value for POD in..
Read MoreAbstract Managing severe (AS) alongside complex (CAD) in frail patients is challenging. A 79-year-old female with resting dyspnea was diagnosed with severe AS and CAD. While (CABG) was the appropriate treatment for CAD,..
Read MoreAbstract Negative pressure ventilation (NPV) has been used to assist patients with respiratory failure. Venovenous extracorporeal membrane oxygenation (V-V ECMO) supports patients with acute lung injury who do not respond..
Read MoreAbstract Background Tranexamic acid (TXA) is recommended for reducing blood loss and transfusion in cardiac surgery. However, there are concerns regarding the safety profile of TXA, especially its proconvulsant effects...
Read MoreAbstract Introduction Bleeding events are common during the provision of Venoarterial ECMO (VA ECMO). Previous observational has suggested that these bleeding events are associated with an increased risk of in-hospital..
Read MoreAbstract BACKGROUND The use of extracorporeal life support (ECLS) in the trauma population remains controversial and has been reported only in small cohort studies. Recent ECLS technical advances have increased..
Read MoreAbstract Background The role of cardiac surgery in octogenarians is debated, but limited data exist for patients aged 65–79. This study compared clinical characteristics, surgical procedures, and outcomes between patients ≥ 80..
Read MoreAbstract Objectives To evaluate ECMO-related morbidity and mortality between Early-term (ET) and Full-term (FT) infants. Methods We performed a retrospective review of 3,831 neonatal ECMO runs for meconium aspiration syndrome..
Read MoreAbstract Objective To investigate the impact of veno-venous extracorporeal membrane oxygenation (VV-ECMO) cannula configuration and ECMO blood flow on intravascular hemodynamic environment, oxygen saturation, hemolysis, and thrombotic risk under varying..
Read MoreAbstract To prevent uncontrolled activation of the hemostatic system and thrombin formation that could be triggered by cardiopulmonary bypass (CPB), unfractionated heparin (hereinafter heparin) is administered to induce profound anticoagulation. Effective..
Read MoreAbstract Aims Cardiac surgery, as an intervention to repair cardiac pathology, may improve frailty, but the evidence is limited. This secondary analysis explored changes in frailty before and 6 months..
Read MoreAbstract Perioperative low cardiac output syndrome (LCOS) remains a significant complication in adult cardiac surgery, contributing to substantial morbidity, prolonged intensive care, and increased mortality. Its incidence is expected to..
Read MoreAbstract Background Pulsatile perfusion is a developing technique that attempts to mimic the natural pulsatile flow of blood during cardiopulmonary bypass (CBP). Purpose This systematic review and meta-analysis was conducted..
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Read MoreAbstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) may reduce mortality and improve neurological outcomes in patients with cardiac arrest. We updated our existing meta-analysis and trial sequential analysis to further evaluate..
Read MoreAbstract Background The optimal arterial cannulation strategy for establishing antegrade cerebral perfusion during aortic arch surgery remains a subject of ongoing debate. Our meta-analysis compares outcomes between axillary artery (AxA)..
Read MoreAbstract Background Family members making decisions about ECMO initiation face high-stakes uncertainty, emotional stress and cultural–ethical dilemmas. However, existing research lacks a synthesised understanding of these decision-making experiences across contexts...
Read MoreAbstract These European Resuscitation Council (ERC) Guidelines 2025 on Special Circumstances in Resuscitation are based on the 2025 Consensus on Science with Treatment Recommendations (CoSTR) of the International Liaison Committee..
Read MoreAbstract Introduction Perfusion accidents still threaten the safety of perfusion during open-heart surgery. To prevent these accidents and increase perfusion safety, it is important to first determine the profile of..
Read MoreAbstract Introduction Partial heart transplantation (PHT) represents a novel and adaptable approach to cardiac surgery, allowing for patient-specific and disease-specific interventions while expanding the donor pool and improving organ stewardship...
Read MoreAbstract Background Extracorporeal membrane oxygenation (ECMO) is a critical, life-sustaining intervention often described as ‘a bridge to nowhere’ due to its transient nature and the ethical complexities it entails. This..
Read MoreAbstract Background This study aimed to analyze the postoperative blood transfusion demand and safety of intraoperative cell salvage (ICS) without leukocyte depletion filters in cesarean sections complicated by placenta previa...
Read MoreAbstract Objective: Coronary artery bypass grafting using cardiopulmonary bypass and cardioplegic arrest is an effective treatment for coronary artery disease. Research suggests supplementing the cardioplegia solution with propofol may be..
Read MoreAbstract Objectives To evaluate whether autologous platelet-rich plasma (aPRP) improves blood conservation and postoperative outcomes in emergency surgery for acute type A aortic dissection (ATAAD). Design Systematic review and meta-analysis..
Read MoreAbstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is one of the most frequent and severe complications after cardiac surgery. The association between acute kidney injury and the mismatch between..
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