Infusion strategy of del Nido cardioplegia for long aortic cross-clamp time in adult cardiac surgery
Abstract Background The del Nido cardioplegia (DNC) solution has been widely used for myocardial protection in adult cardiac surgery, however, its use remains unclear in cases with long aortic cross-clamp..
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Abstract Aims The study explores the association between race, survival and neurological outcomes among out-of-hospital cardiac arrest (OHCA) patients listed in Minnesota metro and the University of Minnesota Extracorporeal Cardiopulmonary..
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Abstract Managing refractory cardiogenic shock is individualized, with few aspects considered routine or universally contraindicated. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a temporary mechanical circulatory support strategy, providing hemodynamic stabilization..
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Abstract Introduction Contrast-induced acute kidney injury (CIAKI) is a common and serious complication of coronary angiography, caused by iodinated contrast agents. It significantly worsens cardiovascular prognosis and increases in-hospital morbidity..
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Abstract Background The association between sex and cardiovascular risk and different responses to heart failure therapies is well established. However, sex related outcomes of different types of short-term mechanical circulatory..
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Abstract Background Extracorporeal cardiopulmonary resuscitation (eCPR) is a new approach for cardiac arrest management and is regarded as a possible alternative for conventional cardiopulmonary resuscitation (cCPR). Aim Our systematic review..
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Abstract Cardiovascular surgery with cardiopulmonary bypass (CPB) is associated with several potential complications, including the activation of inflammatory and coagulation pathways, which may lead to acute kidney injury (AKI). In..
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Abstract Pressure-volume (PV) loop analysis remains the gold standard for studying cardiac physiology by offering a comprehensive analysis and quantitative assessment of the heart. The PV loop analysis uncovers the..
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Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life support technique used in patients with respiratory or cardiac failure. Despite the increased use of ECMO, the incidence and risk factors..
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Abstract Myocardial protection during cardiac surgery is crucial for preventing ischemia-reperfusion injury and preserving myocardial function. Cardioplegia, a solution used to induce electromechanical cardiac arrest, is the fundamental method for..
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Abstract Objectives: Extracorporeal membrane oxygenation (ECMO) plays a crucial role in the outcome of children following surgery for congenital heart disease. However, its availability and affordability are minimal across the globe...
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Abstract Despite evidence-based guidelines to inform platelet transfusion practice, unnecessary platelet transfusion persists. We performed a multicentre retrospective analysis of adults admitted to general medicine, subspecialty medicine and critical care..
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Abstract Background: Acute kidney injury (AKI) is a frequent complication of congenital heart surgery with cardiopulmonary bypass (CPB) in pediatric patients, contributing to significant morbidity and mortality. Aim: To determine..
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Abstract This chapter provides an overview of heparin, including discovery, structure, mechanism of action, and principal use for anticoagulation. For over 100 years, heparin has a central role in prophylaxis..
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Abstract The activated partial thromboplastin time (APTT) assay is essential for evaluating coagulation. However, prolonged APTT may result from pathological conditions or contamination with unfractionated heparin (UFH), which can occur..
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Abstract Introduction Heparin induced thrombocytopenia (HIT) with in paediatric population is rare and subsequent anticoagulation management is challenging. Bivalirudin is a viable alternative to heparin for anticoagulating paediatric patients with..
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Abstract Background Up to half of patients with infective endocarditis (IE) require cardiac surgery. Although anaemia is common, its precise prevalence, transfusion practices and impact on outcomes in surgically treated IE..
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Abstract Objectives CytoSorb, an extracorporeal blood purification device composed of biocompatible, highly porous polymer beads, is being increasingly adopted in different critically ill settings to allow for both enhanced organ..
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Abstract Anticoagulation is mandatory during venoarterial extracorporeal membrane oxygenation (V-A ECMO) flow reduction trials with very low blood flow. Anticoagulation in the ECMO circuit might be intensified with less effect..
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Abstract To synthesize physiological principles and practical monitoring strategies for perioperative and intensive care hemodynamics, addressing two questions: which variables should be monitored, and what targets should be pursued to..
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Abstract Background This study aims to assess the level of ethical distress experienced by intensive care unit (ICU) nurses in their work, thereby providing a theoretical basis for the development..
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Ex Vivo Lung Perfusion (EVLP) has become a key strategy to assess, recondition, and safely transplant lungs from DCD (Donation after Circulatory Death) donors, particularly because of warm ischemia exposure...
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An on-pump veno-arterial (VA) ECMO strategy allows safe stabilization and preparation of a lung-less patient while awaiting immediate implantation of the recipient graft. Following bilateral pneumonectomy, VA ECMO provides full..
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Abstract Background: Postoperative delirium (POD) is known to involve systemic inflammatory responses, but the characteristics of the immune cell types involved in these responses are unclear. Methods: In this prospective study, we..
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Abstract Background: Postoperative thrombocytopenia is a frequent finding after cardiac surgery, affecting approximately 10–40% of patients. The early decline in platelet count, typically observed within the first 48–72 h, is..
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Abstract Background Cardiac arrest (CA) remains a leading cause of mortality and long-term neurological disability. In cases of refractory CA, extracorporeal cardiopulmonary resuscitation (ECPR) may be implemented as a salvage..
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Abstract Objective We aimed to develop and evaluate cardiac surgery–associated acute kidney injury (CSA-AKI) machine learning prediction models that included clinical variables, biomarkers, and high-frequency hemodynamic measurements. Design A prospective,..
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Abstract Objective To investigate the association of Tau protein levels with postoperative evidence of neural injury following cardiopulmonary bypass (CPB) in pediatric cardiac surgery patients. Methods One hundred forty-four consecutive..
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Abstract Background The objective of our study was to evaluate the ability of Emergency Medicine (EM) physicians who have completed an accelerated extracorporeal membrane oxygenation (ECMO) course and mannequin training..
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Abstract The use of extracorporeal cardiopulmonary resuscitation (ECPR) has risen exponentially worldwide. Following favorable observational studies, randomized controlled trials yielded conflicting results in patients with out of hospital cardiac arrest..
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