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Artificial Intelligence in Perioperative Cardiothoracic and Vascular Practice: The Development and Deployment of Assisted and Autonomous Care Options

Abstract The applications of artificial intelligence (AI) in perioperative cardiothoracic and vascular practice continue to grow, given its multiple applications from discovery across translation and integration to delivery of clinical..

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Delirium after Coronary Artery Bypass Grafting: Where We Are Now and Setting Goals for Where We Could Go Next

Abstract Delirium remains a common yet important complication after coronary artery bypass grafting (CABG)., Despite robust research linking delirium to adverse outcomes in this setting, it is still regarded as a..

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Rethinking paracorporeal lung assist device support in the modern era: Why so different than ECMO?

Abstract Background Pediatric patients with combined irreversible pulmonary disease and right ventricular (RV) failure on conventional ECMO face significant challenges with rehabilitation and transplant candidacy. We describe our institutional experience..

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Early Prediction of Neurological Outcome After Cardiac Arrest-Rationale and Design of the Prospective International Observational EARLY-NEURO, a STEPCARE Substudy

Abstract Background Guidelines discourage prediction of neurological outcome in comatose patients within the first 72 h after cardiac arrest. Increasing evidence suggests that patients with the most severe brain injury and..

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Biomechanical anticoagulation by spherical platelets in extracorporeal systems

Abstract Extracorporeal life support, such as hemodialysis, often face the risk of blood coagulation, where systemic anticoagulation with heparin is routinely administered. However, this strategy is contraindicated in patients at..

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The global burden of cardiovascular disease in adults: A mapping review

Abstract The global burden of cardiovascular diseases (CVDs) in adults is increasing. Over the past several decades, CVDs have remained the leading cause of death worldwide. Among CVDs, most mortality..

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Perioperative multivariate analysis and risk prediction of acute kidney injury after cardiac surgery: Based on dynamic temperature changes during cardiopulmonary…

Abstract Background Temperature variations during  (CPB) may significantly contribute to the development and progression of  (AKI) after cardiac surgery. We tested the hypothesis that temperature time-series variables during CPB are associated with..

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NAVA use in infants with established bronchopulmonary dysplasia, congenital diaphragmatic hernia, and those on ECMO: a narrative literature review

Abstract Neurally Adjusted Ventilatory Assist (NAVA) is an innovative mode of ventilation that delivers support in synchrony with the infant’s diaphragmatic electrical activity. This technology aims to improve patient–ventilator interaction,..

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Factor XII in Thrombosis and Thromboinflammation: From Molecular Biology to Clinical Translation

Abstract Factor XII (FXII) is a central mediator at the intersection of coagulation, fibrinolysis, inflammation, and immunity. It is activated upon contact with negatively charged surfaces, triggering the intrinsic coagulation..

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Anaemia: A Scientific Overview on Types and Recent Advancements in the Detection of Anaemia

Abstract Anaemia is the term for low red blood cell numbers or a deficiency of hemoglobin, the protein that carries oxygen in red blood cells. This results in a reduction..

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Effects of Hyperbaric Oxygen Therapy on Myocardial Injury and Inflammatory Biomarkers: A Systematic Review With Qualitative Synthesis

Abstract Myocardial injury is a major predictor of adverse cardiovascular outcomes and is driven by both ischemic and inflammatory mechanisms. Hyperbaric oxygen therapy (HBOT), which delivers 100% oxygen at supra-atmospheric..

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Ross(-Konno) Procedure in Neonates and Infants: A Multicentre Experience

Abstract Objectives Neonates and infants who receive a Ross or Ross-Konno operation form a different population from older children and adults who undergo this procedure. We aimed to provide a..

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Applying randomized control trial criteria to an ECPR cohort

Abstract Objective To assess how inclusion criteria from major randomized controlled trials (RCTs) of extracorporeal cardiopulmonary resuscitation (ECPR) apply within a cannulated ECPR cohort and to benchmark observed outcomes against..

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Sweep Flow Nitric Oxide Effects on Coagulation, Inflammation, and Endothelial System Activation During Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) can trigger a systemic inflammatory response syndrome (SIRS) with activation of inflammatory, endothelial, and coagulation system pathways. We assessed in a randomized trial whether a)..

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The adsorptive property of HA380 hemoperfusion in inflammation alleviation during cardiopulmonary bypass

Abstract Clinically, the inflammation induced by cardiopulmonary bypass (CPB) is associated with a higher incidence of severe complications and mortality. Based on the absorptive property of hemoperfusion, it has been..

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Perioperative Glucose Pragmatic (PROGRAM) Trial: Standardized Insulin Management in Surgical Patients

Abstract Background: Perioperative hyperglycemia is associated with adverse patient outcomes including surgical site infections. This study examined whether an automated insulin dosing reminder is associated with a lower risk for..

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Association Between Ionized Calcium Concentrations During Weaning From Cardiopulmonary Bypass and Postoperative Low Cardiac Output Syndrome: A Retrospective Cohort Study

Abstract BACKGROUND:  Weaning from cardiopulmonary bypass (CPB) is a critical step in cardiovascular surgery. Although ionized calcium (iCa) plays a crucial role in myocardial contractility, and hypocalcemia commonly occurs during..

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Short-Term Outcomes of Intra-Aortic Balloon Pump vs. Microaxial Flow Pump for Fulminant Myocarditis Supported by Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background: The clinical differences between intra-aortic balloon pumping (IABP) and a microaxial flow pump (Impella) for left ventricular (LV) unloading in patients with fulminant myocarditis (FM) supported with venoarterial extracorporeal..

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Intravenous Dabigatran for Anticoagulation during Cardiopulmonary Bypass in a Sheep Model

Abstract Background: Heparin is the standard anticoagulant used during cardiopulmonary bypass (CPB). However, there are problems with heparin, including immunogenicity and variability of effect, that make a search for an..

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Trends in Neonatal Extracorporeal Membrane Oxygenation (ECMO) in New York State: 2018-2024

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) has been used in the care of critically ill neonates since the 1970s. Some neonatal ECMO indications include inadequate tissue oxygen delivery, severe hypoxic..

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Lactic alkalosis in a patient on veno-venous extracorporeal membrane oxygenation: A case report

Abstract Background: Lactic alkalosis, defined as an increase in circulating lactate in the setting of elevated extracellular pH, has been described in both in vivo and in vitro settings, often..

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Novel Use of a Distal Perfusion Catheter With a Removable Side Port in Patients on VA-ECMO

Abstract Risk of limb ischemia in patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) is minimized with the use of distal perfusion catheters (DPCs). However, conventional sheaths utilize a flow-limiting side..

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Cost-effectiveness of extracorporeal CPR for out-of-hospital cardiac arrest: a trial-based Markov model with a lifetime horizon

Abstract Aims Extracorporeal cardiopulmonary resuscitation (ECPR) can restore circulation in refractory out-of-hospital cardiac arrest (OHCA). A trial-based analysis with a 1-year horizon showed limited cost-effectiveness of this demanding procedure. However,..

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The Year in Coagulation and Transfusion: Selected Highlights

Abstract The past year has yielded important advances in coagulation and transfusion practice across cardiothoracic and vascular care. Patient blood management remains central, with growing evidence supporting restrictive transfusion thresholds,..

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Cardiac surgery in Chile: preoperative risk characterization and analytical outcomes pre-operative risk characterization in cardiac surgeries

Abstract Background Cardiovascular diseases are the leading cause of mortality worldwide, including in Chile, accounting for about 23% of all deaths. Advanced cardiac surgical procedures like coronary artery bypass grafting..

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Oxygenator oxygen transfer performance during cardiopulmonary bypass of the Sorin® Inspire 6F©

Abstract Background Oxygenator oxygen transfer performance is typically measured by manufacturers under standardized, static laboratory conditions. However, these parameters do not adequately reflect the dynamic environment of clinical cardiopulmonary bypass..

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Quantitative Electroencephalogram Patterns During Neonatal Antegrade Cerebral Perfusion and Deep Hypothermic Circulatory Arrest that Suggest Neurologic Injury

Abstract During cerebral ischemia, the quantitative Electroencephalogram (EEG) Alpha: Delta Ratio (ADR) decreases, and the asymmetry percentage increases. The utility of analyzing these metrics during neonatal Antegrade Cerebral Perfusion (ACP)..

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Special 3 day Rescue Team Course Paris - Nov 30/ 2 Dec

Special 3 day Rescue Team Course Paris NEXT SESSION 30 November to 2 December 2026 Come learn all you need to know on OHCA, ECPR and REBOA during a 3-day..

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Guiding complexity in V-A ECMO weaning decisions for cardiogenic shock: Insights from a conjoint analysis

Abstract Weaning and liberation from V-A ECMO for cardiogenic shock involves complex decision-making that requires balancing multiple clinical parameters. In the absence of specific weaning guidelines, ECMO centers rely on..

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Heparin Exposure Adjustment to Reduce Thrombo-hemorrhagic Complications After Venoarterial Extracorporeal Membrane Oxygenator Cannulation: The HEART-ECMO Observational Cohort Study

Abstract Objectives Hemorrhagic complications remain a major concern in patients with cardiogenic shock and extracorporeal cardiopulmonary resuscitation. The purpose of this study was to assess the effect of withholding a..

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