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Revisiting Acute Respiratory Distress Syndrome ventilation management: Time for a paradigm shift focusing on tidal volume

Abstract: Merola and colleagues critically evaluate current Acute Respiratory Distress Syndrome (ARDS) ventilation strategies, emphasizing limitations inherent in universally applying low tidal volume (VT) strategies. They argue for personalized, physiology-driven ventilation approaches that...

Physical and respiratory therapy in the critically ill patient with obesity: a narrative review

Abstract: Martínez-Camacho et al. discuss the critical aspects of physical and respiratory therapy for obese patients in the ICU, highlighting the complexities of obesity-related respiratory and metabolic disturbances. They emphasize the importance of early mobilization, meticulous ventilatory...

Managing Intracranial Pressure Crisis

Abstract: Viarasilpa provides a comprehensive review of current strategies for managing intracranial pressure (ICP) crises, emphasizing critical care management, ICP monitoring, neuromonitoring, and evidence-based therapeutic approaches. The review integrates protocols from the Brain Trauma...

Management of cardiogenic shock: state-of-the-art

Abstract: Jung et al. provide a comprehensive review addressing current knowledge and contemporary practices in the management of cardiogenic shock (CS). Despite advancements, mortality remains high, and the complexity of patient care underscores the need for individualized treatments. The authors...

Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised…

Abstract: Endo et al. conducted the OPTPRESS trial, a multicenter randomized controlled trial in Japan, evaluating whether a higher mean arterial pressure (MAP) target (80–85 mmHg) reduces mortality in older patients (≥65 years) with septic shock compared to standard targets (65–70 mmHg). The trial...

Intraoperative extracorporeal support for lung transplant: a systematic review and network meta-analysis

Abstract: Pettenuzzo et al. conducted a systematic review and network meta-analysis evaluating the efficacy and safety of intraoperative extracorporeal supports—veno-arterial extracorporeal membrane oxygenation (V-A ECMO) and cardiopulmonary bypass (CPB)—compared to off-pump strategies during lung...
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