Abstract Objective:This study aimed to evaluate school-age neurodevelopmental outcomes among children with single ventricle heart disease who underwent neonatal Norwood operation with regional cerebral perfusion compared to deep hypothermic circulatory..
Read MoreAbstract Allogeneic red blood cells (RBCs) are commonly used for cardiopulmonary bypass (CPB) circuit priming in congenital heart surgery. While convection-based pre-bypass ultrafiltration (PBUF) corrects acid–base, electrolyte, and metabolite imbalances,..
Read MoreAbstract Background Despite the widespread adoption of selective antegrade cerebral perfusion (SACP) for neonatal aortic arch reconstruction, significant variability in techniques persists across institutions, thus reflecting limited supporting data and..
Read MoreAbstract Therapeutic plasma exchange (TPE) in pediatric patients presents many challenges, including management of a large extracorporeal volume (ECV) and calcium replacement for patients who may not be able to..
Read MoreAbstract Background The experience of a percutaneous microaxial (Impella) in children with is limited. The primary objective of this study was to review our institutional clinical outcomes of Impella use in children..
Read MoreAbstract Aims Academic achievement of children with congenital heart disease (CHD) has not been comprehensively studied across the entire CHD severity spectrum. Methods and results Through nationwide registries, we identified..
Read MoreAbstract Congenital diaphragmatic hernia (CDH) is a rare and severe malformation that can lead to life-threatening postnatal physiological challenges which may require lifesaving extracorporeal membrane oxygenation (ECMO) support, sometimes more..
Read MoreAbstract Background Young patients may survive accidental deep hypothermia with prolonged asystolic circulatory arrest because of protective effects of cold. Case Summary An 8-year-old boy fell through pond ice and..
Read MoreAbstract Background Delayed sternal closure (DSC) is a well-established management strategy following complex congenital cardiac surgery that is used to mitigate postoperative hemodynamic and respiratory instability. It is mostly used..
Read MoreAbstract Background There is geographic disparity in the provision of Pediatric and Congenital Heart Disease (PCHD) services; Africa accounts for only 1% of global cardiothoracic surgical capacity. Methods We conducted..
Read MoreAbstract To investigate the feasibility of regional oxygen saturation (rSO2) monitoring for preventing acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) caused by cardiopulmonary bypass (CPB) in infants undergoing ventricular..
Read MoreAbstract Background: The gold standard for treatment of patients with end-stage heart failure remains . Time spent on the active waiting list, notably for patients, contributes to alarmingly high mortality. Donation after..
Read MoreAbstract Objective To describe cardiac arrest during anesthesia care provided by a pediatric cardiac anesthesiologist in patients with congenital heart disease and identify predictors of outcome. Design Retrospective chart review...
Read MoreAbstract Purpose Extracorporeal cardiopulmonary resuscitation (ECPR) is an advanced resuscitation therapy for cardiopulmonary arrest refractory to standard CPR. ECPR treatment recommendations are not supported by strong evidence, and institutional criteria..
Read MoreAbstract This study aimed to assess whether the proinflammatory markers procalcitonin (PCT), C-reactive protein (CRP), or interleukin 6 (IL-6) are associated with mortality in neonates with congenital diaphragmatic hernia (CDH)..
Read MoreAbstract Importance Studies suggest that everolimus may reduce the risk of rejection, cardiac allograft vasculopathy (CAV), chronic kidney disease (CKD), and cytomegalovirus (CMV) after heart transplant. Everolimus use is controversial because..
Read MoreAbstract Nutritional support in pediatric patients receiving extracorporeal membrane oxygenation (ECMO) therapy is controversial. Although ECMO is increasingly used in pediatric intensive care units, there is no consensus on the..
Read MoreAbstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a notably common complication in pediatrics, with an incidence rate ranging from 15 to 64%. This rate is significantly higher than..
Read MoreAbstract Introduction Bleeding and thrombosis are major causes of morbidity and mortality in pediatric extracorporeal membrane oxygenation (ECMO), yet their evolving, time-dependent risks remain poorly defined. This study evaluated clinical..
Read MoreAbstract Extubation of select neonatal and pediatric patients supported with extracorporeal membrane oxygenation (ECMO) may avoid ventilator-induced lung injury, decrease neurosedative exposure, and improve rehabilitation. A single-center retrospective cohort study..
Read MoreAbstract Background Cardiac allotransplantation is the optimal treatment for end-stage heart failure. However, organ supply remains the principal issue affecting patients. Pediatric patients present unique challenges resulting in long wait-list..
Read MoreAbstract Background Children undergoing cardiopulmonary bypass (CPB) surgery are vulnerable to bleeding and often require transfusions. Pathogen-reduced (PR) platelets may reduce microbial contamination but are associated with decreased platelet count..
Read MoreAbstract Background: To investigate the factors that influence blood transfusions after neonatal cardiac surgery and their association with prolonged mechanical ventilation (PMV) to provide a basis for optimizing blood transfusion..
Read MoreAbstract The emergence of large language models (LLMs) opens new horizons to leverage, often unused, information in clinical text. Our study aims to capitalise on this new potential. Specifically, we..
Read MoreAbstract Background Acute kidney injury (AKI) and dysnatremia following pediatric cardiac surgery are common conditions associated with worse outcomes. While the multifactorial etiology of AKI is well-known, the role of..
Read MoreAbstract Background To evaluate the effect and safety of modified ultrafiltration warming technology during pediatric congenital heart disease (CHD) surgery. Methods A retrospective analysis included 68 children (<1 year) who..
Read MoreAbstract Digital ischemia following extracorporeal membrane oxygenation (ECMO) therapy is a known complication with potential devastating long-term sequela. Onabotulinum toxin type A (BTX-A) has been demonstrated to be effective for..
Read MoreAbstract Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list times and resultant..
Read MoreAbstract Background: Data is limited regarding the effects of supraphysiologic blood oxygen tension (hyperoxia) in patients requiring extracorporeal life support (ECLS). We sought to evaluate the association between hyperoxia and..
Read MoreAbstract Introduction This study aims to describe laboratory and clinical factors associated with thrombotic events during prolonged pediatric extracorporeal membrane oxygenation. Methods A secondary analysis of a multi-center prospective study..
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