Archives

Perfusfind S.L.

Abstract Background Neonatal cardiac surgery is associated with high morbidity and mortality. Perioperative metabolic stress may result in distinct metabolic phenotypes associated with adverse clinical outcomes. Objectives The purpose of..

Perfusfind S.L.

Abstract Objective: To describe surgical outcomes, in-hospital mortality, and variables associated with mortality in pediatric patients with congenital heart disease (CHD) at a national referral center in México over 14..

Perfusfind S.L.

Abstract Importance  Cyanotic congenital heart diseases, which occur in approximately 0.2% of live births in the United States, have high mortality rates if untreated, but survival to adulthood is common with..

Perfusfind S.L.

Abstract Neurological injury remains a major concern during neonatal aortic arch surgery. Near-infrared spectroscopy (NIRS) is commonly used to monitor cerebral oxygenation but does not provide direct quantitative information on..

Perfusfind S.L.

Abstract Background Optimal oxygenation strategies during cardiopulmonary bypass (CPB) in children with cyanotic congenital heart disease remain controversial. Although hyperoxia has traditionally been used to compensate for chronic hypoxemia, concerns..

Perfusfind S.L.

Abstract Background and Aims Adults with congenital heart disease tend to develop both cardiac and noncardiac age-related comorbidities earlier in life than the general population, suggesting accelerated biological ageing. Epigenetic..

Perfusfind S.L.

Abstract Objectives To identify risk factors associated with inadequate heparin response in pediatric congenital heart surgery requiring cardiopulmonary bypass and to develop age-specific predictive scoring systems. Design Retrospective cohort study...

Perfusfind S.L.

Abstract Congenital heart disease (CHD) is the most common congenital anomaly worldwide and is associated with substantial infant morbidity and mortality. This narrative review synthesizes evidence linking CHD to alterations..

Perfusfind S.L.

Abstract Importance  Neurodevelopmental impairments are common in children with congenital heart disease. Objectives  To compare neurodevelopmental outcomes by cardiac diagnosis and identify associations between medical and social factors and early neurodevelopmental outcomes..

Perfusfind S.L.

Abstract Background Discovered in 1938, haptoglobin is a liver-produced α2-glycoprotein that binds free hemoglobin, mitigating its toxic effects, and serves as a biomarker for hemolysis. The current study, under the..

Perfusfind S.L.

Abstract Background In 2019, the American Society of Extracorporeal Technology (AmSECT) approved the inaugural Standards and Guidelines for Pediatric and Congenital Perfusion Practice. These standards and guidelines were created with the..

Perfusfind S.L.

Abstract Effective perioperative hemostasis in pediatric cardiac surgery depends not only on accurate diagnostics and targeted transfusion strategies but also on a clear and consistent definition of postoperative bleeding. Despite..

Perfusfind S.L.

Abstract Aim Congenital heart disease still has significant morbidity and mortality despite advances in surgery. Inadequate tissue perfusion is thought to be the primary cause. Monitoring children with cerebral oxygenation..

Perfusfind S.L.

Abstract Background: Pediatric cardiac surgery is still a high-risk procedure, with mortality being a significant concern. Lactate clearance has been demonstrated to enhance outcomes in critically ill adult populations; however, data..

Perfusfind S.L.

Abstract Background Congenital heart disease (CHD) remains a leading cause of pediatric morbidity and mortality worldwide. Cardiopulmonary bypass (CPB) is crucial for surgical repair but is associated with systemic inflammation..

Perfusfind S.L.

Abstract As adult programs of newer anthrombotic agents, such as those directed against FXIa, are underway, there is both a pressing need and a great opportunity to optimize the design,..

Perfusfind S.L.

Abstract Congenital heart disease often requires early surgical intervention. Cardiopulmonary bypass (CPB) is a standard procedure, but infants undergoing CPB show an increased risk of postoperative white matter injury. These..

Perfusfind S.L.

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for refractory paediatric in-hospital cardiac arrest (IHCA). Although rapid initiation of extracorporeal life support (ECLS) is widely considered critical, the relative..

Perfusfind S.L.

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) for pediatric cardiac arrest relies on enhanced resources and time-critical decision-making. We aimed to evaluate variations in systems and clinical practice among extracorporeal membrane oxygenation..

Perfusfind S.L.

Abstract Objectives Neonates and infants who receive a Ross or Ross-Konno operation form a different population from older children and adults who undergo this procedure. We aimed to provide a..

Perfusfind S.L.

Abstract During cerebral ischemia, the quantitative Electroencephalogram (EEG) Alpha: Delta Ratio (ADR) decreases, and the asymmetry percentage increases. The utility of analyzing these metrics during neonatal Antegrade Cerebral Perfusion (ACP)..

Perfusfind S.L.

Abstract Background Children with cyanotic congenital heart disease undergoing cardiac surgery with cardiopulmonary bypass (CPB) are exposed to varying oxygenation strategies, and the optimal oxygenation strategy and the impact of..

Perfusfind S.L.

Abstract Background: Neonates and young infants undergoing cardiac surgery with cardiopulmonary bypass (CPB) are highly vulnerable to pulmonary dysfunction, systemic inflammation, capillary leak, and fluid overload, which may lead to..

Perfusfind S.L.

Abstract This case report describes a pediatric cardiac surgery in which electrocardiographic (ECG) changes appeared immediately after the initiation of cardiopulmonary bypass (CPB), followed by severe bradycardia and ultimately flaccid..

Perfusfind S.L.

Abstract Background Retrograde autologous priming and venous antegrade priming replace the cardiopulmonary bypass circuit crystalloid with patient blood to mitigate hemodilution. However, their effectiveness in pediatric patients, particularly when analyzed..

Perfusfind S.L.

Abstract Purpose Pediatric patients undergoing cardiac surgery are at risk of developing postoperative acute kidney injury (AKI). We hypothesized that a reduction in intraoperative renal (SrO2) or cerebral (ScO2) tissue..

Perfusfind S.L.

Abstract Background We implemented a preoperative screening brain magnetic resonance imaging (MRI) protocol for neonates undergoing cardiac surgery. The intent was to identify unrecognized central nervous system (CNS) injury that..

Perfusfind S.L.

Abstract Background: Sanguineous preparation of the cardiopulmonary bypass (CPB) circuit with allogeneic blood products is known to contain substantial complement mediator burden. This study aims to assess the longitudinal immunologic impacts..

Perfusfind S.L.

Abstract Antegrade cerebral perfusion (ACP) and hypothermia are widely used neuroprotective strategies during neonatal aortic arch repairs. Still, over 50% of neonates exhibit new or worsened white matter injury in..

Perfusfind S.L.

Abstract Background: A 17-year-old male patient diagnosed with a single ventricle, in a failed Fontan stage, was evaluated prior to heart transplantation. The patient had a panel-reactive antibody (PRA) for..