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Prothrombotic Microvesicle Generation in Pediatric Cardiopulmonary Bypass: A Pilot Observational Study

Abstract Over 10% of children develop thrombosis after cardiac surgery for congenital heart disease. Children with a single ventricle physiology have the highest risk of thrombosis associated with increased length..

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The Association Between Platelet Transfusion and Acute Kidney Injury Following Fontan Surgery

Abstract Objectives: Previous studies have demonstrated an association between transfusion and increased organ dysfunction. We sought to determine the association between transfusion of blood components (red blood cell [RBC], plasma, platelet,..

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Comprehensive surgical technique for the neonatal and infant Ross Konno procedure – technical pearls

Abstract The Ross Konno procedure is a technically demanding operation in neonates and infants, particularly in small babies and those with significant aortic annular and left ventricular outflow tract hypoplasia...

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Perioperative extracorporeal membrane oxygenation in neonates with transposition of the great arteries: 15 years of experience

Abstract OBJECTIVES Extracorporeal membrane oxygenation (ECMO) can act as a bridge to recovery in both pre- and postoperative patients with transposition of the great arteries (TGA). However, literature on its..

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Timing of venoarterial extracorporeal membrane oxygenation in infant cardiac surgery: a single-centre retrospective study of clinical outcomes

Abstract Background Venoarterial extracorporeal membrane oxygenation (VA ECMO) is a critical therapeutic intervention that is commonly used in the management of paediatric patients with congenital heart disease (CHD). This procedure..

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Use of Inhaled Tranexamic Acid for Pulmonary Hemorrhage in Pediatric Patients on Extracorporeal Membrane Oxygenation Support

Abstract Bleeding is a common complication of extracorporeal membrane oxygenation (ECMO), is multifactorial, and results in significant morbidity and mortality. Pulmonary hemorrhage represents a serious adverse event in pediatric patients..

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Racial and Sex Disparities in Incidence, Risk Factors, and Outcomes of Neonatal Extracorporeal Life Support in the United States

Abstract The impact of race on extracorporeal life support (ECLS) availability, morbidity, and mortality remains poorly defined. We sought to define the impact of race/ethnicity, sex, and location on ECLS..

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Neonatal venoarterial extracorporeal membrane oxygenation cannulation technique

Peripheral cannulation for initiation of neonatal venoarterial extracorporeal membrane oxygenation is an essential technical skill in the armamentarium of every congenital cardiac surgeon and is necessary for the care of..

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Pump‐controlled retrograde trial off extracorporeal membrane oxygenation

Venoarterial extracorporeal membrane oxygenation weaning strategies are not standardized. When dealing with patients with complex physiologies and borderline haemodynamics, it is prudent to have a fail-safe method of approaching decannulation..

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Trends in Cardiac Arrest Outcomes & Management in Children with Cardiac Illness Category Compared to Non-Cardiac Illness Category: An Analysis…

Abstract Introduction Contemporary rates of survival after pediatric in-hospital CPR events and trends in survival over the last 20 years have not been compared based on illness category. We hypothesized that..

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Urine biomarkers, acute kidney injury, and fluid overload in neonatal cardiac surgery

Abstract Background:Cardiac surgery-associated acute kidney injury (CS-AKI) and fluid overload (FO) are common among neonates who undergo cardiopulmonary bypass, and increase mortality risk. Current diagnostic criteria may delay diagnosis. Thus,..

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Daily Surveillance Blood Cultures in Children Supported With Extracorporeal Membrane Oxygenation: Single-Center, Retrospective Cohort Study, 2021–2023

Abstract Objective:  Diagnosing bloodstream infections (BSIs) in patients on extracorporeal membrane oxygenation (ECMO) can be challenging due to circuit-controlled temperature, altered hemodynamics, and questionable reliability of inflammatory markers in critically..

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Perioperative extracorporeal membrane oxygenation in neonates with transposition of the great arteries: 15 years of experience

Abstract OBJECTIVES Extracorporeal membrane oxygenation (ECMO) can act as a bridge to recovery in both pre- and postoperative patients with transposition of the great arteries (TGA). However, literature on its..

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The first case of central Y–Y extra-corporeal membrane oxygenation system in a pediatric patient

Abstract The mechanical circulatory support (MCS) for pediatric patients with severe acute heart failure and poor pulmonary conditions is challenging. Herein, we report the first pediatric case of successfully treated..

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Implementation of Bundled Interventions to Reduce Surgical Site Infections in Pediatric Patients Undergoing Cardiothoracic Surgery: A Quality Improvement Project

Abstract Pediatric patients undergoing cardiothoracic surgery are at increased risk for health care–associated infections, especially surgical site infections (SSIs). Delayed sternal closures are associated with prolonged lengths of stay and..

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Best Practices for Vessel Management in Pediatric Extracorporeal Membrane Oxygenation Cannulation, Decannulation, and Follow-up: A Narrative Review

Abstract Extracorporeal membrane oxygenation (ECMO) to support neonates and children with cardiopulmonary failure was first described in the 1970s, since which time its use has expanded to an increasingly complex..

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CO2 field-flooding devices offer potential value for cardiopulmonary bypass procedures for CHD performed via a right-side small incision approach

Abstract Objective This study sought to evaluate the value of a CO2 field-flooding device in cardiopulmonary bypass (CPB) surgical procedures for congenital heart disease (CHD) performed via a right-side small incision..

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Development and validation of a nomogram for predicting perioperative transfusion in children undergoing cardiac surgery with CPB

Abstract Background Timely recognition of perioperative red blood cell transfusion (PRT) risk is crucial for developing personalized blood management strategies in pediatric patients. In this study, we sought to construct..

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Extracorporeal membrane oxygenation for Chinese neonates with severe respiratory and cardiac failure

Abstract Objective We aimed to outline the experience with extracorporeal membrane oxygenation (ECMO) for respiratory and cardiac failure in neonates in our institution and compare our results with those from..

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Outcomes in Children Who Undergo Postcardiotomy Extracorporeal Membrane Oxygenation: A Report From the STS-CHSD

Abstract Background Children who undergo cardiac surgery may require postcardiotomy extracorporeal membrane oxygenation (ECMO). Although morbidities are considerable, our understanding of outcome determinants is limited. We evaluated associations between patient..

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Early Use Experience of the Crescent Right Atrial Cannula for Neonatal Veno-Venous Extracorporeal Membrane Oxygenation

Abstract Veno-venous (VV) extracorporeal membrane oxygenation (ECMO) is associated with fewer neurological complications and decreased mortality compared to veno-arterial (VA) ECMO in neonatal respiratory failure. The Crescent right atrial (RA)..

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Randomized Trial of Pulsatile and Nonpulsatile Flow in Cyanotic and Acyanotic Congenital Heart Surgery

Abstract Background The study objective was to determine the impact of cardiopulmonary bypass perfusion modalities on cerebral hemodynamics and clinical outcomes in congenital cardiac surgery patients stratified by acyanotic versus..

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Application comparison of paediatric myocardial protection procedures in arterial switch surgery

Abstract Background Reliable myocardial protection is essential for a good outcome after arterial switch operation. Patients and Methods We evaluated 56 neonates with arterial switch operation in this retrospective study...

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Short term outcomes of the first pediatric cardiac surgery program in Rwanda

Abstract Background While the number of cardiac surgery programs in sub-Saharan Africa are increasing, it is still insufficient. With only 0.08 pediatric cardiac surgeons per million people, few cardiac centers..

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Preoperative Serum Ferritin Level and Acute Kidney Injury after Pediatric Cardiac Surgery

Abstract Background Acute kidney injury (AKI) is a significant complication in pediatric patients undergoing cardiac surgery. Iron metabolism-related indicators such as ferritin may predict AKI after adult cardiac surgery. However, it..

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Using artificial intelligence to predict post-operative outcomes in congenital heart surgeries: a systematic review

Abstract Introduction Congenital heart disease (CHD) represents the most common group of congenital anomalies, constitutes a significant contributor to the burden of non-communicable diseases, highlighting the critical need for improved..

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Factors associated with activated clotting time following heparin administration in pediatric cardiopulmonary bypass: A retrospective study

Abstract Introduction The recently recommended activated clotting time (ACT) to be maintained at the initiation of and during cardiopulmonary bypass (CPB) is ≥480 s. However, the post-unfractionated heparin (UFH) administration ACT..

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A randomized study on the impact of optimized modified ultrafiltration on the physiological parameters of infants and children undergoing a…

Abstract Background The aim of this study is to assess the impact of optimized modified ultrafiltration (OMUF) on the physiological parameters of infants and children undergoing cardiopulmonary bypass (CPB). Methods..

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“Extracorporeal membrane oxygenation outcomes in multisystem inflammatory syndrome of childhood – An extracorporeal life support organization registry study”

Abstract Multisystem inflammatory disease in childhood (MIS-C) is a novel pediatric syndrome after a COVID-19 infection that causes systemic injury, with potential life-threatening hemodynamic compromise requiring Extracorporeal Membrane Oxygenation (ECMO)..

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Unifocalization of Major Aortopulmonary Collateral Arteries (MAPCAs) and Native Pulmonary Arteries in Infancy—Application of 3D Printing and Virtual Reality

Abstract Background. Major aortopulmonary collateral arteries (MAPCAs) are rare remnants of pulmonary circulation embryological development usually associated with complex congenital anomalies of the right ventricular outflow tract and pulmonary arteries...

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