Abstract Background: The gold standard for treatment of patients with end-stage heart failure remains . Time spent on the active waiting list, notably for patients, contributes to alarmingly high mortality. Donation after..
Read MoreAbstract Objective To describe cardiac arrest during anesthesia care provided by a pediatric cardiac anesthesiologist in patients with congenital heart disease and identify predictors of outcome. Design Retrospective chart review...
Read MoreAbstract Purpose Extracorporeal cardiopulmonary resuscitation (ECPR) is an advanced resuscitation therapy for cardiopulmonary arrest refractory to standard CPR. ECPR treatment recommendations are not supported by strong evidence, and institutional criteria..
Read MoreAbstract This study aimed to assess whether the proinflammatory markers procalcitonin (PCT), C-reactive protein (CRP), or interleukin 6 (IL-6) are associated with mortality in neonates with congenital diaphragmatic hernia (CDH)..
Read MoreAbstract Importance Studies suggest that everolimus may reduce the risk of rejection, cardiac allograft vasculopathy (CAV), chronic kidney disease (CKD), and cytomegalovirus (CMV) after heart transplant. Everolimus use is controversial because..
Read MoreAbstract Nutritional support in pediatric patients receiving extracorporeal membrane oxygenation (ECMO) therapy is controversial. Although ECMO is increasingly used in pediatric intensive care units, there is no consensus on the..
Read MoreAbstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a notably common complication in pediatrics, with an incidence rate ranging from 15 to 64%. This rate is significantly higher than..
Read MoreAbstract Introduction Bleeding and thrombosis are major causes of morbidity and mortality in pediatric extracorporeal membrane oxygenation (ECMO), yet their evolving, time-dependent risks remain poorly defined. This study evaluated clinical..
Read MoreAbstract Extubation of select neonatal and pediatric patients supported with extracorporeal membrane oxygenation (ECMO) may avoid ventilator-induced lung injury, decrease neurosedative exposure, and improve rehabilitation. A single-center retrospective cohort study..
Read MoreAbstract Background Cardiac allotransplantation is the optimal treatment for end-stage heart failure. However, organ supply remains the principal issue affecting patients. Pediatric patients present unique challenges resulting in long wait-list..
Read MoreAbstract Background Children undergoing cardiopulmonary bypass (CPB) surgery are vulnerable to bleeding and often require transfusions. Pathogen-reduced (PR) platelets may reduce microbial contamination but are associated with decreased platelet count..
Read MoreAbstract Background: To investigate the factors that influence blood transfusions after neonatal cardiac surgery and their association with prolonged mechanical ventilation (PMV) to provide a basis for optimizing blood transfusion..
Read MoreAbstract The emergence of large language models (LLMs) opens new horizons to leverage, often unused, information in clinical text. Our study aims to capitalise on this new potential. Specifically, we..
Read MoreAbstract Background Acute kidney injury (AKI) and dysnatremia following pediatric cardiac surgery are common conditions associated with worse outcomes. While the multifactorial etiology of AKI is well-known, the role of..
Read MoreAbstract Background To evaluate the effect and safety of modified ultrafiltration warming technology during pediatric congenital heart disease (CHD) surgery. Methods A retrospective analysis included 68 children (<1 year) who..
Read MoreAbstract Digital ischemia following extracorporeal membrane oxygenation (ECMO) therapy is a known complication with potential devastating long-term sequela. Onabotulinum toxin type A (BTX-A) has been demonstrated to be effective for..
Read MoreAbstract Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list times and resultant..
Read MoreAbstract Background: Data is limited regarding the effects of supraphysiologic blood oxygen tension (hyperoxia) in patients requiring extracorporeal life support (ECLS). We sought to evaluate the association between hyperoxia and..
Read MoreAbstract Introduction This study aims to describe laboratory and clinical factors associated with thrombotic events during prolonged pediatric extracorporeal membrane oxygenation. Methods A secondary analysis of a multi-center prospective study..
Read MoreAbstract Objectives To ascertain the dosage of bivalirudin in neonates and infants undergoing arterial switch operation on integrated extracorporeal membrane oxygenation–cardiopulmonary bypass (CPB) circuit. Design Pilot study. Setting A tertiary..
Read MoreAbstract Objectives: Blood lactate concentration ([Lac]b) reflects the balance among production, clearance (Cl[Lac]), and volume of distribution. We have observed dramatic improvement in [Lac]b in critically ill patients after starting support..
Read MoreAbstract To evaluate the impact of hospital-acquired infections ( HAIs ) on the prognosis of neonates treated with extracorporeal membrane oxygenation (ECMO) and analyzing related prognostic indicators, we conducted a..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is an important rescue strategy for neonates with severe cardiorespiratory failure, yet its role in the management of hypoxic–ischemic encephalopathy (HIE) remains subject to debate...
Read MoreAbstract OBJECTIVES Acute kidney injury commonly complicates congenital heart surgery with cardiopulmonary bypass, increasing morbidity and mortality. This study aimed to evaluate risk factors for postoperative acute kidney injury and..
Read MoreAbstract Purpose The purpose of this systematic review was to identify the efficacy of cell salvage in adult and pediatric spinal surgery. Methods A comprehensive systematic review of four biomedical..
Read MoreAbstract Aims Pediatric cardiac arrest is associated with high mortality and significant morbidity among survivors. International guidelines for prognostication remain limited due to small heterogeneous patient populations, variable post-return of..
Read MoreAbstract Poor or worsening functional status of lung transplant (LTx) candidates is a key risk factor for waitlist and post-transplant mortality. As more critically ill adults and children are listed..
Read MoreAbstract The storing of dry-assembled and primed extracorporeal membrane oxygenation (ECMO) circuits is common practice and endorsed by the Extracorporeal Life Support Organization (ELSO) for up to 30 days. We..
Read MoreAbstract In neonates with pulmonary hypertension (PH) supported on veno-venous extracorporeal membrane oxygenation (VV-ECMO), keeping the ductus arteriosus (DA) open ensures a high cardiac output of well-oxygenated blood through the..
Read MoreAbstract Purpose Neonates undergoing cardiopulmonary bypass (CPB) are at a high risk of a systemic inflammatory response leading to cardiac, respiratory, and renal dysfunction due to their small body size..
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