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Guideline on pregnant and peripartum extracorporeal membrane oxigenation, Elso 2025 Narrative

At the time of publication of this guideline, the leading causes of maternal death for pregnant and peripartum patients include hemorrhage, infection, eclampsia, thromboembolism, and cardiac disease. Not only are these..

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Endothelial Activation and Permeability in Patients on VV-ECMO Support: An Exploratory Study

Abstract Background Veno-venous extracorporeal membrane oxygenation (VV-ECMO) supports critically ill patients with respiratory failure. However, ECMO may induce systemic inflammation, hemolysis, and hemodilution, potentially resulting in endothelial activation and damage. Therefore,..

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An initiative to reduce blood stream infections (BSI) in patients on ECMO

Abstract Introduction Blood Stream Infections (BSI) occur in 3-35% of patients on ECMO (Extracorporeal membrane Oxygenation). With the increased use of ECMO since the COVID-19 pandemic, the magnitude of this..

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Single venous cannulation for bi-atrial venoarterial extracorporeal membrane oxygenation in bridge to transplantation: a two-in-one approach

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) often leads to left ventricular (LV) overload, particularly in patients with biventricular cardiogenic shock. This increased afterload can hinder cardiac muscle recovery and cause..

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Activated Clotting Time and Haemostatic Complications in Patients Receiving ECMO Support: A Systematic Review

Abstract Background: Extracorporeal membrane oxygenation (ECMO) requires systemic anticoagulation to prevent clotting, typically using unfractionated heparin (UFH). However, anticoagulation carries a bleeding risk, necessitating monitoring. Activated clotting time (ACT) is..

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Global Survey of Extracorporeal Membrane Oxygenation Transport Programs: Variability in Team Composition, Training, and Capabilities

Abstract Extracorporeal membrane oxygenation (ECMO) is a form of cardiopulmonary support associated with improved survival in severe respiratory failure and refractory cardiac arrest. Extracorporeal membrane oxygenation is highly specialized and..

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Prognostic scores of extracorporeal membrane oxygenation: a scoping review

Abstract BACKGROUND: Extracorporeal membrane oxygenation (ECMO) is an effective measure for saving the lives of critically ill patients. Prompt identification of the risk factors for mortality among patients receiving ECMO and..

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Re-evaluating the association between thrombocytopenia and bleeding in extracorporeal membrane oxygenation (ECMO)

Abstract Objectives The platelet trigger at which to transfuse platelets to prevent bleeding complications in patients supported with extracorporeal membrane oxygenation (ECMO) is unclear. We aimed to elucidate the association..

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Impact of Preoperative Extracorporeal Membrane Oxygenation Use on Lung Transplant Outcomes

Abstract Background  (ECMO) may be used to support critically ill patients before . The relationship between preoperative venoarterial and venovenous ECMO and their relationship with  indications remain poorly elucidated. Methods This study..

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Venovenous Extracorporeal Membrane Oxygenation Cannulation by Intensivists and Surgeons: A Single-Center Retrospective Noninferiority Analysis of Complications and Outcomes From 2018…

Abstract Objectives:  To evaluate the safety and efficacy of venovenous extracorporeal membrane oxygenation (ECMO) cannulation by nonsurgeon intensivists (critical care medicine intensivists [CCM]) compared with cardiothoracic surgeons (CTS). Design:  Retrospective,..

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In-Hospital Outcomes and Readmissions in High-Risk Pulmonary Embolism Patients Requiring Extracorporeal Membrane Oxygenation Support

Abstract There are limited data on the use of extracorporeal membrane oxygenation (ECMO) in high-risk pulmonary embolism (PE) patients. We analyzed the use of ECMO in high-risk PE patients (defined..

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Hyperoxia and End-Organ Complications Among Cardiogenic Shock Patients Supported by Veno-Arterial Extracorporeal Membrane Oxygenation

Abstract Abstract Objectives:  To investigate whether severe hyperoxia predisposes to end-organ complications and whether these complications contribute to in-hospital mortality among cardiogenic shock (CS) patients supported in veno-arterial extracorporeal membrane..

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Extracorporeal membrane oxygenation cannula dressing and securement practices: A point prevalence study

Abstract Background Effective securement of extracorporeal membrane oxygenation (ECMO) cannulae, both at the insertion site and along the length of circuit tubing, may reduce the risk of cannula migration, dislodgement,..

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Investigating the Impact of Cannula Size on Pump Operation and Hemodynamics in an In Silico Clinical Trial

Abstract Veno-arterial extracorporeal membrane oxygenation (V‑A ECMO) is a critical care therapy for patients with severe cardiorespiratory failure, and it is associated with high in‑hospital mortality rates. Causes are the..

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Use of Temporary Ventricular Assist Devices for Left Ventricular Unloading During Venoarterial Extracorporeal Membrane Oxygenation Support

Venoarterial extracorporeal membrane oxygenation (VA ECMO) provides temporary mechanical circulatory support for patients in refractory cardiogenic shock. Initiation of VA ECMO often results in increased left ventricular (LV) afterload as..

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Clinical Outcomes of Cardiogenic Shock Patients Supported with VA-ECMO: Insights from the Cardiogenic Shock Working Group

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) use for cardiogenic shock (CS) is increasing worldwide despite conflicting results from randomized trials, which focused on myocardial-infarction related CS (MI-CS). Methods We..

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Aortic Balloon Occlusion in Circulatory Determination of Death Donors Undergoing Abdominal Normothermic Regional Perfusion?

Abstract Normothermic regional perfusion (NRP) is a strategy of postmortem reperfusion with warm oxygenated blood of a portion of the body applied in donors undergoing circulatory determination of death (DCDDs)...

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Risk factors for bleeding and thrombotic complications during extracorporeal membrane oxygenation support in adults based on the MIMIC-IV database

Abstract Objective:   To identify risk factors for bleeding and thrombotic complications during extracorporeal membrane oxygenation (ECMO) support in adults and to develop a predictive model based on these factors...

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Extracorporeal life support for adult patients with ARDS

Abstract Extracorporeal Life Support (ECLS), including venovenous (VV) extracorporeal membrane oxygenation (ECMO) and extracorporeal carbon dioxide removal (ECCO2R) is a temporary support option for patients with severe respiratory failure. Current..

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Incidence, kinetics, and clinical impact of thrombocytopenia in venovenous ECMO: insights from the multicenter observational PROTECMO study

Abstract Background Thrombocytopenia is a recognized risk factor for bleeding during extracorporeal membrane oxygenation (ECMO). This study determines the incidence, risk factors, and clinical relevance of thrombocytopenia and platelet transfusions..

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Storage duration of packed red blood cells transfused during veno-venous extracorporealmembrane oxygenation is associatedwith elevated pulmonary artery pressureand lung injury…

Abstract Background Veno‑venous extracorporeal membrane oxygenation (VV‑ECMO) is associated with a high transfusion burden. While trials have concluded that red blood cell (RBC) storage does not impact patient morbidity and..

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Crescent jugular dual-lumen catheter for adult veno-venous extracorporeal membrane oxygenation in China: Multicenter initial experience

Abstract Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is a life support technique used for patients with life-threatening respiratory failure. It effectively addresses arterial hypoxemia without overstretching the injured lungs. Traditional..

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Pharmacological Research Agenda on Adult Extracorporeal Membrane Oxygenation Using the Delphi Method: A Position Article of the Extracorporeal Membrane Oxygenation…

Abstract Objectives:  Extracorporeal membrane oxygenation (ECMO) is a critical intervention for patients with severe cardiac or respiratory failure. However, pharmacological management for ECMO-supported patients presents unique challenges due to alterations..

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Optimal ECLS Support in Mixed Cardiogenic and Septic Shock: An ELSO Registry Analysis

Abstract Background Mixed cardiogenic and septic shock has been shown to have a higher mortality than cardiogenic shock alone and presents a unique hemodynamic phenotype. Objectives This study aimed to..

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Patients Post Cardiac Surgery Requiring Venoarterial Extracorporeal Membrane Oxygenation: Outcomes From an Intensivist-Led Extracorporeal Membrane Oxygenation Program

Abstract Post cardiac surgery shock (PCS) is a life-threatening condition that may require the use of mechanical circulatory support. Venoarterial (VA) extracorporeal membrane oxygenation (ECMO) is increasingly used to treat..

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Outcomes of Patients Requiring VA-ECMO for Cardiogenic Shock and Evaluation of Programmatic Changes

Abstract Objectives To describe outcomes in patients who received venoarterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock and to evaluate outcomes following programmatic changes. Design A retrospective cohort study. Setting..

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Flow of Data, Not Blood Flow, Is the Key to Unraveling ECMO Support in Mixed Shock

Abstract Mixed shock has been identified by the Shock Academic Research Consortium (SHARC) as a “high-risk, understudied population”. It develops in around one-quarter of patients with cardiogenic shock and has a higher..

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Current intraoperative mechanical circulatory support strategies for bilateral lung transplantation surgery

Abstract Objective To discuss technical strategies and considerations to facilitate intraoperative extracorporeal membrane oxygenation (ECMO) management during lung transplantation. Methods We review our institutional approach to the management of intraoperative..

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Venovenous extracorporeal membrane oxygenation with mechanical chest compression for cardiopulmonary resuscitation: A porcine model study

Abstract Objective To evaluate the effectiveness of venovenous (VV) extracorporeal membrane oxygenation (ECMO) using a dual-lumen cannula coupled with continuous mechanical chest compressions (cMCC) for cardiopulmonary resuscitation and compare it..

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A Continuous, Real-Time Coagulation State Monitor for ECMO Patients

Abstract For patients undergoing extracorporeal membrane oxygenation (ECMO), clot formation is a critical complication requiring high-risk circuit changes. Blood tests used to assess clotting risk may be drawn only four..

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