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Red blood cell transfusion practices in extracorporeal membrane oxygenation: A single-center study

Abstract Objectives Evaluating blood transfusion practices and their impact on morbidity and mortality across extracorporeal membrane oxygenation (ECMO) configurations. Background As ECMO becomes increasingly utilised in critical care, the ideal..

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Investigation of contamination and environmental exposure of cold/heated water supply systems for extracorporeal circulation used in ECMO and other applications

Abstract Infection cases have been reported where Legionella spp. and NTM (non-tuberculous mycobacteria) increased due to the contamination of circulating water in cold/heated water supply systems for extracorporeal circulation used in cardiac..

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New Findings on Pulsatile ECMO: Verification of the Potential to Improve Antithrombogenicity of a Membrane Oxygenator Using Pump-Generated Pulsatile Flow…

Abstract Background Extracorporeal membrane oxygenation (ECMO) provides mechanical circulatory and respiratory support. However, thrombus formation in the circuit can lead to hemorrhagic complications, requiring improvements in ECMO anti-thrombogenicity. Few studies..

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Successful Treatment of Extracorporeal Membrane Oxygenation Induced Digital Ischemia in Infants Using Botulinum Toxin Type A

Abstract Digital ischemia following extracorporeal membrane oxygenation (ECMO) therapy is a known complication with potential devastating long-term sequela. Onabotulinum toxin type A (BTX-A) has been demonstrated to be effective for..

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Minimally invasive, transapical dual-lumened cannula for short-term left ventricular support in a clinically relevant large animal model†

Abstract OBJECTIVES Cardiogenic shock is still a major clinical challenge, despite the available devices. We developed a minimally invasive, transapical dual-lumened cannula, which can provide antegrade circulatory support and unloading..

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Is hyperoxia in early pediatric veno-veno extracorporeal life support associated with mortality?

Abstract Background: Data is limited regarding the effects of supraphysiologic blood oxygen tension (hyperoxia) in patients requiring extracorporeal life support (ECLS). We sought to evaluate the association between hyperoxia and..

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Mortality and Complications in Hybrid Extracorporeal Membrane Oxygenation: A Meta-Analysis of Initial Use Versus Transition

Abstract Hybrid extracorporeal membrane oxygenation (ECMO), containing additional ECMO cannulations in addition to conventional ECMO, is increasingly used for the treatment of serious cardiopulmonary conditions. Patients initiating non-hybrid ECMO may..

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Critical hematological parameters in bleeding during extracorporeal membrane oxygenation support

Abstract Bleeding complications are frequently observed in patients undergoing extracorporeal membrane oxygenation and are associated with increased mortality. Due to the complex mechanisms, managing bleeding during ECMO remains a challenge...

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Comprehensive secondary analysis of thrombotic events in pediatric patients receiving extracorporeal membrane oxygenation: A prospective cohort study

Abstract Introduction This study aims to describe laboratory and clinical factors associated with thrombotic events during prolonged pediatric extracorporeal membrane oxygenation. Methods A secondary analysis of a multi-center prospective study..

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Veno-Arterial Extracorporeal Membrane Oxygenation in Cardiotoxic Drug-Induced Cardiogenic Shock: A Systematic Narrative Review

Abstract Background: Severe poisoning can lead to catastrophic cardiovascular collapse, often progressing to multiorgan failure and death. While intensive supportive care and pharmacological intervention remain the cornerstone of management, cases of..

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Cycle ergometers in extracorporeal membrane oxygenation patient rehabilitation: A scoping review

Abstract Introduction The aim of this scoping review was to determine what evidence is available regarding the use of the cycle ergometer in the rehabilitation of adult patients undergoing extracorporeal..

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Near-Infrared Spectroscopy for Preventing Limb Ischemia in Extracorporeal Membrane Oxygenation

Abstract Background Limb ischemia is a serious complication of venoarterial (VA) extracorporeal membrane oxygenation (ECMO), potentially resulting in amputation, rhabdomyolysis, or death. This study aimed to evaluate the effectiveness of..

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Total thyroidectomy performed under general anesthesia with venovenous extracorporeal membrane oxygenation during a thyroid storm: a case report

Abstract Thyroid storm (TS) is an endocrine emergency requiring aggressive medical management. In severe cases, hemodynamic instability may necessitate extracorporeal membrane oxygenation (ECMO) support as a bridge to definitive surgical..

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Redefining weaning in a VA ECMO: a case report on pump-controlled retrograde trial off

Abstract Extracorporeal membrane oxygenation (ECMO) is widely recognized as a life-saving measure. The use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) is on the rise, serving as an effective mechanical..

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Visualizing Flow Dynamics in a Human Aorta During Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Treatment Through Particle Image Velocimetry Study

Abstract Purpose To build a mock circulatory loop to simulate veno-arterial extracorporeal membrane oxygenation (V-A ECMO) haemodynamics using a patient-specific silicone aortic phantom and compare the flow dynamics for continuous..

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The Impact of the COVID-19 Pandemic on Intensive Care Nurses' Experience in Providing Extracorporeal Membrane Oxygenation Care

Abstract To explore the challenges and describe the impact of the COVID-19 pandemic on intensive care nurses' experience in providing ECMO care in a high-volume Australian ICU ECMO centre that..

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Heparin-free veno-venous ECMO for airway obstruction: A case report and review of literature

Abstract Rationale:  Life-threatening airway obstructions caused by tumors demand prompt and effective intervention. Traditional surgical methods are often complicated by bleeding risks, especially with the use of anticoagulation during extracorporeal..

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Machine Learning–Based First-Day Mortality Prediction for Venoarterial Extracorporeal Membrane Oxygenation: The Novel RESCUE-24 Score

Abstract Extracorporeal membrane oxygenation (ECMO) provides critical cardiac support, but predicting outcomes remains a challenge. We enrolled 1,748 adult venoarterial (VA)-ECMO patients at the National Taiwan University Hospital between 2010..

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Weight Categories Have no Impact on Mortality in Patients Treated with Extracorporeal Membrane Oxygenation (ECMO)

Abstract Background Extracorporeal Membrane Oxygenation (ECMO) is a critical support system for patients with acute and severe cardiac and respiratory failure. This study investigates the impact of different patient body..

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The effects of extracorporeal blood purification (oXiris®) in patients with cardiogenic shock who require VA-ECMO (CLEAN ECMO): a prospective, open-label,…

Abstract Background A systemic inflammatory response can contribute to poor outcomes in an advanced stage of cardiogenic shock (CS). We investigated the efficacy of extracorporeal endotoxin and cytokine adsorption using..

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Evaluation of Intraoperative Bivalirudin Anticoagulation in Neonates and Infants Undergoing Arterial Switch Operation on Integrated ECMO-CPB Circuit: A Prospective Study

Abstract Objectives To ascertain the dosage of bivalirudin in neonates and infants undergoing arterial switch operation on integrated extracorporeal membrane oxygenation–cardiopulmonary bypass (CPB) circuit. Design Pilot study. Setting A tertiary..

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Hyperlactatemia in Critically Ill Children: Modeling Early Recovery Kinetics After Initiation of Extracorporeal Membrane Oxygenation

Abstract Objectives:  Blood lactate concentration ([Lac]b) reflects the balance among production, clearance (Cl[Lac]), and volume of distribution. We have observed dramatic improvement in [Lac]b in critically ill patients after starting support..

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Canonical flow structures formed in a diagonal pump used in extracorporeal membrane oxygenation

Abstract This study focuses on the fluid dynamics of a blood pump used in extracorporeal membrane oxygenation (ECMO). In ECMO, the patient's blood is pumped through a circuit composed of..

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Hospital-acquired infections in neonatal ECMO patients: a systematic review and meta-analysis

Abstract To evaluate the impact of hospital-acquired infections ( HAIs ) on the prognosis of neonates treated with extracorporeal membrane oxygenation (ECMO) and analyzing related prognostic indicators, we conducted a..

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Endovascular Management for Accidental Cannulation of the Left Ascending Lumbar Vein with an Extracorporeal Membrane Oxygenation Catheter: A Case Report

Abstract The femoral vein is frequently used for central venous access during extracorporeal membrane oxygenation (ECMO). Accidental cannulation of the ascending lumbar vein (ALV) during ECMO has rarely been reported...

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ECMO Use in Neonates with Hypoxic–Ischemic Encephalopathy

Abstract Extracorporeal membrane oxygenation (ECMO) is an important rescue strategy for neonates with severe cardiorespiratory failure, yet its role in the management of hypoxic–ischemic encephalopathy (HIE) remains subject to debate...

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The effects of extracorporeal bloodpurification (oXiris®) in patientswith cardiogenic shock who require VA-ECMO.

Abstract Background A systemic inflammatory response can contribute to poor outcomes in an advanced stage of cardiogenic shock (CS). We investigated the efficacy of extracorporeal endotoxin and cytokine adsorption using..

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Characterizing Microbiome Changes in Veno-Venous Extracorporeal Membrane Oxygenation: A Case Report of Multidrug-Resistant Bacteremia

Abstract Microbiome analysis using metagenomics next-generation sequencing (mNGS) is rarely performed in patients receiving extracorporeal membrane oxygenation (ECMO). Patient body sites were swabbed within 72 hours of ECMO cannulation and..

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Extracorporeal membrane oxygenation (ECMO): A narrative review for the emergency clinician

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) is an established therapy that supports a patient in respiratory or cardiopulmonary failure to recovery, transplant, or durable mechanical support. Prompt referral by the..

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Rare complication of extracorporeal membrane oxygenation cannula misplacement into the hepatic vein: A case report Li K, Pan XJ, Liu…

Abstract BACKGROUND Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is a lifesaving intervention for severe respiratory failure; however, its effectiveness depends on accurate cannulation-patients with anatomical variations present with significant challenges..

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