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Perfusfind S.L.

Abstract High-pressure excursions (HPE) during cardiopulmonary bypass (CPB) are rare but potentially life-threatening events linked to coagulation activation, inflammation. Known risk factors include male sex, large body surface area (BSA),..

Perfusfind S.L.

Abstract Objectives To compare myocardial protection afforded by three single-dose cardioplegic solutions — Custodiol (HTK), del Nido (DN) and modified del Nido (MDN) — in adult elective cardiac surgery. Design Double-blind randomised..

Perfusfind S.L.

Abstract Background: Discussions continue on the ideal priming fluid in adult cardiac surgery. The purpose of this prospective study was to evaluate the effects of different types of priming fluids..

Perfusfind S.L.

Abstract Background While hyperoxia has conventionally been the standard during cardiopulmonary bypass (CPB) to prevent hypoxemia, recent concerns regarding oxygen-induced oxidative stress have sparked debate over whether a normoxic strategy..

Perfusfind S.L.

Abstract Introduction: Providing sufficient organ perfusion during cardiopulmonary bypass (CPB) is a common research topic among extracorporeal technology researchers. The application of an elevated cardiac index (CI) to enhance CPB..

Perfusfind S.L.

Abstract Background Ultrafiltration is integral to cardiopulmonary bypass, yet the optimal replacement fluid for zero-balance ultrafiltration requires further investigation to guide clinical practice. This study aimed to compare the efficacy..

Perfusfind S.L.

Abstract Background Cardiopulmonary bypass (CPB) oxygenators provide essential intra-operative gas exchange. Although rare, CPB oxygenator failures can cause catastrophic morbidity and mortality, and published analyses of CPB-specific oxygenator failures are..

Perfusfind S.L.

Abstract Objectives Cardiopulmonary bypass (CPB) impairs endothelial function, causing oedema and disturbed microcirculatory perfusion, that contribute to organ dysfunction following cardiac surgery. We hypothesised that the composition of CPB prime..

Perfusfind S.L.

Abstract Objective To assess the non-inferiority of topical intrapericardial tranexamic acid (TXA) versus intravenous TXA for efficacy and safety in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods In..

Perfusfind S.L.

Abstract Background Oxygenator failure during cardiopulmonary bypass (CPB) is a rare but potentially catastrophic intraoperative event that can result in sudden hypoxemia and neurological injury if not promptly recognized and..

Perfusfind S.L.

Abstract Purpose This study aimed to evaluate the clinical effects of sodium bicarbonate Ringer’s solution(BRS) as a priming fluid for cardiopulmonary bypass (CPB). Methods A total of 159 patients undergoing..

Perfusfind S.L.

Abstract Background: Cardiopulmonary bypass (CPB) is an essential technique for cardiac surgery but significantly increases the risk of perioperative neurological complications. Electroencephalography (EEG) enables real-time monitoring of brain function and..

Perfusfind S.L.

Abstract Objectives Neurological complications after cardiac surgery have been associated with gaseous microemboli generated during cardiopulmonary bypass. We undertook a trial to assess whether a novel dual-chamber oxygenator, designed to..

Perfusfind S.L.

Abstract Background Neurocognitive decline (NCD) after cardiopulmonary bypass is a well-established phenomenon. While numerous preoperative risk factors have been identified, the influence of intraoperative factors on NCD still needs further..

Perfusfind S.L.

Abstract In cardiac surgery operations with cardiopulmonary bypass (CPB), patients are connected to a heart-lung machine and the patient's blood comes into contact with nonphysiological extracorporeal circulation equipment. Aims: In..

Perfusfind S.L.

Abstract Background Thoracoabdominal aortic aneurysm (TAAA) repair is associated with significant risks of blood loss and organ ischemia. This study evaluates the efficacy of a novel, modified Extracorporeal Circulation (mECC)..

Perfusfind S.L.

Abstract Objectives Cardiopulmonary bypass (CPB) is essential to cardiac surgery but is associated with organ injury from non-physiological perfusion. Goal-directed perfusion (GDP) has emerged as a physiology-based strategy to optimize..

Perfusfind S.L.

Abstract Objective Vasoplegia and endothelial dysfunction are well-known complications of cardioplegia and cardiopulmonary bypass (CP/CPB). Our lab has previously shown that endothelial adherens junction impairment is driven by vascular endothelial..

Perfusfind S.L.

Abstract Background Temperature variations during  (CPB) may significantly contribute to the development and progression of  (AKI) after cardiac surgery. We tested the hypothesis that temperature time-series variables during CPB are associated with..

Perfusfind S.L.

Abstract BACKGROUND:  Weaning from cardiopulmonary bypass (CPB) is a critical step in cardiovascular surgery. Although ionized calcium (iCa) plays a crucial role in myocardial contractility, and hypocalcemia commonly occurs during..

Perfusfind S.L.

Abstract Background Oxygenator oxygen transfer performance is typically measured by manufacturers under standardized, static laboratory conditions. However, these parameters do not adequately reflect the dynamic environment of clinical cardiopulmonary bypass..

Perfusfind S.L.

Abstract Background Pericardiectomy is a definitive treatment for constrictive pericarditis. However, the extent of resection and cardiopulmonary bypass (CPB) use remain debated. We therefore compared hemodynamic changes, complications, long-term survival,..

Perfusfind S.L.

Serum lactate is a critical biomarker in cardiac surgery, offering insights into tissue oxygenation and metabolic status. Elevated lactate levels during cardiopulmonary bypass (CPB) can indicate inadequate perfusion, hypoxia, or..

Perfusfind S.L.

Abstract Background: Minimizing Gaseous microemboli (GME) introduced into the CPB circuit can help alleviate neurologic injury. This study focuses on understanding how suction flow rate and the reservoir level can..

Perfusfind S.L.

Abstract Background: The accuracy and precision of continuous in-line blood gas monitoring (CILBGM) are crucial for optimal blood gas management during cardiopulmonary bypass (CPB) and improved patient outcomes. CILBGM devices,..

Perfusfind S.L.

Abstract Objectives This study aimed to evaluate the hemodynamic impact and cost-effectiveness of a standardized protocol for refractory vasoplegia occurring after cardiopulmonary bypass (CPB). Design Observational, pre-post study. Setting A..

Perfusfind S.L.

Abstract Introduction: Despite the advances in CPB, various complications may occur. Prediction and anticipation of these undesirable outcomes is of great importance. For this reason, various markers have been tried to..

Perfusfind S.L.

Abstract The administration of cardioplegia is a core component of the multimodal approach to myocardial protection during cardiac surgery with cardiopulmonary bypass., An ideal cardioplegia solution should facilitate rapid cardiac arrest,..

Perfusfind S.L.

Abstract Introduction: During cardiopulmonary bypass (CPB), adequate prime solution allows pre-treatment of the tubing line, oxygenator and blood pump, evacuation of air from the arterial conduit, and appropriate blood dilution. However,..

Perfusfind S.L.

Abstract Objective Near Infra-Red Spectroscopy (NIRS), can be used to monitor renal tissue oxygenation (SrO2), as well as thenar muscle oxygenation (SmO2). In this study, we have examined the ability of..