Archives

Perfusfind S.L.

Abstract Background Patient Blood Management (PBM) is a multidisciplinary strategy to optimise patient outcomes by preserving autologous blood and reducing unnecessary transfusion. Although PBM initiatives exist worldwide, the consistency of..

Perfusfind S.L.

Abstract Coagulopathy, bleeding, and transfusion of allogeneic blood products remain major concerns in a relevant portion of patients undergoing cardiac surgery, and all of them have been associated with increased..

Perfusfind S.L.

Abstract Study Question To describe the blood product utilization during neonatal and pediatric extracorporeal membrane oxygenation (ECMO) and to determine whether its usage correlates with clinical outcomes of bleeding, thrombosis..

Perfusfind S.L.

Abstract Transfusions are one of the most common procedures performed in the hospital setting, but the frequency of adverse events is often not recognized. These transfusion adverse events include transfusion..

Perfusfind S.L.

Abstract Patient Blood Management (PBM) has evolved from a transfusion-centered practice to a structured, patient-focused perioperative strategy aimed at improving surgical outcomes while preserving blood resources. In the operating room,..

Perfusfind S.L.

Abstract Background Traumatic or surgical hemorrhage causes substantial morbidity and mortality. Electrical vagus nerve stimulation (VNS) reduces traumatic hemorrhage in animal models. VNS targets acetylcholine-producing T lymphocytes in the spleen..

Perfusfind S.L.

Abstract Background Jehova′s Witnesses refuse the administration of allogenic blood products for religious reasons. This stance represents a special challenge for the perioperative management and requires individualized ethically sensitive and..

Perfusfind S.L.

Abstract Patient blood management (PBM) aims to improve patient outcome by managing and preserving a patient’s own blood and its components. Among the many recommended interventions, reducing intraoperative blood loss..

Perfusfind S.L.

Abstract Background: Postoperative thrombocytopenia is a frequent complication in cardiac surgery, associated with increased morbidity and mortality. Our study aimed to describe platelet count after cardiac surgery and identify predictors..

Perfusfind S.L.

Abstract Andexanet alfa (Ondexxya) currently holds UK marketing authorisation (MA) for adult patients treated with a direct factor Xa (FXa) inhibitor (apixaban or rivaroxaban) when reversal of anticoagulation is indicated..

Perfusfind S.L.

Abstract Objectives To compare postoperative platelet counts in patients in whom intraoperative cell salvage (ICS) was performed using either a centrifugation-based device (ICS-centrifugation) or a filtration-based device (ICS-filtration; Same) for..

Perfusfind S.L.

Abstract Viscoelastic testing (VET), recommended for heart surgery, lacks adoption due to data reporting times (central laboratory coagulation assay-CLCA and laboratory VET tests) and interpretation (predicate VET devices). Three point..

Perfusfind S.L.

Abstract Critically ill patients often require complex extracorporeal treatments, such as extracorporeal blood purification (EBP). At the bedside, there can be reluctance or uncertainty about when to initiate EBP, and..

Perfusfind S.L.

Abstract Background The Emergency Bypass System (EBS, Terumo Corporation) and Permanent Life Support (PLS, MAQUET Cardiopulmonary GmbH) platforms differ in pump design and surface coating, which may influence hemocompatibility. This study..

Perfusfind S.L.

Abstract Blood clots are pivotal for haemostasis and regeneration, but they are mechanically weak and form slowly, posing risks for life-threatening haemorrhage and limiting broader applications,,. These limitations are attributed..

Perfusfind S.L.

Abstract Introduction Bleeding and clotting phenotypes are common in patients supported with Extracorporeal Membrane Oxygenation (ECMO) and are associated with increased mortality. However, tools to distinguish bleeding from clotting phenotypes..

Perfusfind S.L.

Abstract Despite the advances in technology, new patient populations, new medications, and multiple monitoring algorithms for anticoagulation, bleeding, and thrombosis complications remain high among those receiving extracorporeal life support (ECLS)..

Perfusfind S.L.

Abstract Background Pediatric cardiac surgery with cardiopulmonary bypass (CPB) carries substantial transfusion requirements, exposing patients to increased risks of complications during hospital stay. This study evaluates the clinical impact of..

Perfusfind S.L.

Abstract Background There is no universally accepted definition of perioperative blood loss in cardiac surgery. Existing methods are based on chest tube output and are not normalised for patient weight...

Perfusfind S.L.

Abstract Open thoracoabdominal aortic aneurysm repair (TAAAR) is associated with mortality rates of between 8% and 25%. One of the characteristics of TAAAR is massive bleeding that requires multiple units..

Perfusfind S.L.

Abstract Anaemia is the term for low red blood cell numbers or a deficiency of hemoglobin, the protein that carries oxygen in red blood cells. This results in a reduction..

Perfusfind S.L.

Abstract The past year has yielded important advances in coagulation and transfusion practice across cardiothoracic and vascular care. Patient blood management remains central, with growing evidence supporting restrictive transfusion thresholds,..

Perfusfind S.L.

Abstract Background Intraoperative cell salvage (CS) reduces allogeneic transfusion in cardiac surgery but depletes coagulation factors, potentially causing dose-dependent coagulopathy. Although mechanistic studies suggest hemostatic impairment at higher volumes, nearly..

Perfusfind S.L.

Abstract Objectives Postcardiopulmonary bypass bleeding is frequent and distinctive because of its associated coagulopathy. Despite diagnostic and therapeutic progress, substantial variability persists in hemostatic transfusion practices. Because transfusion of hemostatic..

Perfusfind S.L.

Abstract Background Bleeding and thrombosis are major complications of micro-axial flow pump (mAFP) support in cardiogenic shock (CS), yet contemporary data on their incidence, temporal trends, and prognostic impact remain..

Perfusfind S.L.

Abstract Background Major bleeding is a common and serious complication of veno-arterial extracorporeal membrane oxygenation (VA ECMO). Current perspectives on bleeding risk fail to reflect dynamic changes over time in..

Perfusfind S.L.

Abstract Introduction: During cardiopulmonary bypass (CPB), adequate prime solution allows pre-treatment of the tubing line, oxygenator and blood pump, evacuation of air from the arterial conduit, and appropriate blood dilution. However,..

Perfusfind S.L.

Abstract Heart failure is a significant complication of chronic intravascular hemolysis, a condition characterized by red blood cells (RBCs) breakdown, leading to the release of acellular hemoglobin (Hb) and its..

Perfusfind S.L.

Abstract Background Postoperative bleeding following cardiopulmonary bypass (CPB) remains a significant challenge. Although viscoelastic testing is increasingly used, the relative contributions of fibrinogen, platelet count and clot firmness to blood..

Perfusfind S.L.

Abstract Objective This study assessed the impact of intraoperative goal-directed fluid therapy integrated within an Enhanced Recovery After Surgery program on early coagulation parameters, transfusion requirements, hemoglobin levels, chest tube..