Abstract Background Postoperative bleeding is a major concern in cardiac surgery, often leading to significant transfusion requirements. Despite this high transfusion demand, the use of postoperative autologous blood transfusion (PABT)..
Read MoreAbstract Cancer surgery accounts for a substantial proportion of allogeneic blood use. As demographic changes lead to a growing number of oncologic procedures, transfusion demands are increasing, while blood supply..
Read MoreAbstract Heart transplantation (HT) is the definitive therapy for end-stage heart failure. Patients unwilling to receive blood product transfusions are often considered ineligible for HT due to the significant perioperative..
Read MoreAbstract Objectives Bleeding is a common complication of extracorporeal membrane oxygenation (ECMO) support. While chest tube treatment is infrequently linked to bleeding in non-ECMO patients, several reports suggest a markedly..
Read MoreAbstract Background Fibrinogen concentrate may reduce allogeneic blood product transfusion in cardiac surgery patients with bleeding associated with acquired hypofibrinogenemia. The European Society of Anaesthesiology and Intensive Care (ESAIC) has..
Read MoreAbstract The utilisation of cardiopulmonary bypass (CPB) during cardiac surgery is often associated with complex haemostatic perturbations, frequently manifesting as a paradoxical risk of both bleeding and thrombosis. This is..
Read MoreAbstract Objectives To evaluate whether platelet function is preserved after intraoperative autotransfusion using the Same system, a device designed to retain both red blood cells and platelets in patients undergoing..
Read MoreAbstract The anticoagulant proteins antithrombin, protein C, protein S, and tissue factor pathway inhibitor are physiological regulators of the blood coagulation pathway and have complex roles in causing or modifying..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is increasingly being utilized in critical care globally to allow for adequate oxygenation in patients with cardiac and/or respiratory failure. Unfortunately, haemostatic complications – both..
Read MoreAbstract Background The optimal haemoglobin threshold for use of red blood cell (RBC) transfusions in anaemic patients remains an active area of research. Blood is a limited resource, and there..
Read MoreAbstract Treating severe lung diseases with extracorporeal membrane oxygenation (ECMO) is often accompanied by serious complications, restricting applicability and adversely affecting outcomes. Membrane oxygenators, based on hollow fiber membranes (HFM),..
Read MoreAbstract Purpose Fibrinogen is widely used in cardiac surgery. Still, reported associations between plasma fibrinogen level and chest tube drainage are weak. The results of trials on fibrinogen supplementation are..
Read MoreAbstract Pumping blood through an extracorporeal membrane oxygenation (ECMO) circuit in critically ill patients inevitably leads to a pathophysiological response characterized by platelet and procoagulant activation, fibrin deposition, and immunomodulation. This..
Read MoreAbstract Purpose Postoperative bleeding is a major concern in pediatric cardiac surgery under cardiopulmonary bypass (CPB). The comparative utility of viscoelastic testing and central laboratory assays for predicting bleeding risk..
Read MoreAbstract Introduction Patients who undergo cardiac surgery have a high risk of significant blood loss and anemia. While allogeneic red blood cell (RBC) transfusions are effective, they are associated with..
Read MoreAbstract Background Tranexamic acid (TXA) is recommended for reducing blood loss and transfusion in cardiac surgery. However, there are concerns regarding the safety profile of TXA, especially its proconvulsant effects...
Read MoreAbstract Introduction Bleeding events are common during the provision of Venoarterial ECMO (VA ECMO). Previous observational has suggested that these bleeding events are associated with an increased risk of in-hospital..
Read MoreAbstract Background This study aimed to analyze the postoperative blood transfusion demand and safety of intraoperative cell salvage (ICS) without leukocyte depletion filters in cesarean sections complicated by placenta previa...
Read MoreAbstract Objectives To evaluate whether autologous platelet-rich plasma (aPRP) improves blood conservation and postoperative outcomes in emergency surgery for acute type A aortic dissection (ATAAD). Design Systematic review and meta-analysis..
Read MoreAbstract Objectives Activated recombinant factor VII (rFVIIa) has been used to treat cardiac surgical bleeding in an off-label manner. Due to the high risk of mortality with ongoing hemorrhage, assessing..
Read MoreAbstract Objective To determine the state of patient blood management (PBM) practice in leading US cardiac surgery centers. Design A survey tool addressing PBM program structure and PBM program operations..
Read MoreAbstract Background: The purpose of this survey was to delineate and compare patient blood management (PBM) approaches in cardiac surgery across nine Middle Eastern countries while identifying the main challenges..
Read MoreAbstract Background Blood is a biological, irreplaceable, and perishable resource, provided through voluntary, altruistic, and free donation in Brazil. Although blood components are widely used in hospital settings, several challenges..
Read MoreAbstract Background: Low hematocrit level is a hematological problem that is frequently encountered during cardiopulmonary bypass (CPB) in patients undergoing on-pump coronary artery bypass grafting (CABG). This study aimed to..
Read MoreAbstract Purpose Coagulopathy is a common perioperative complication in aortic surgery, increasing the risk of bleeding and transfusion requirements. This study aimed to evaluate the impact of autologous plateletpheresis on..
Read MoreAbstract Background Patients on heart transplant waiting lists are often on antithrombotic (AT) drugs. Emergency orthotopic heart transplantation (OHT) when performed on such patients without optimal washout periods increases the..
Read MoreAbstract Background has become a first-line adjunctive therapy for in patients with acute intermediate-risk (PE). This prospective study evaluated the safety and efficacy of percutaneous mechanical with autologous blood reinfusion using the next-generation..
Read MoreAbstract Background: Revision hip arthroplasty is associated with significant blood loss and a subsequent need for blood transfusion. Intraoperative cell salvage (ICS) is a method of recovering a patient’s blood..
Read MoreAbstract Objective This systematic review aims to evaluate the extensive application of platelet-rich plasma (PRP) as a novel autologous cell therapy across various clinical disciplines in recent years. Method A..
Read MoreAbstract Globally, postpartum hemorrhage is still among the most significant factors in preventable maternal morbidity and mortality. Although early recognition and intervention have improved with advances in obstetric care, transfusion..
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