Archives

Perfusfind S.L.

Abstract Introduction: Red blood cell (RBC) transfusions are frequent in cardiac surgery and are associated with higher morbidity, mortality, prolonged hospitalization, and increased healthcare costs. Several patient- and procedure-related factors have..

Perfusfind S.L.

Abstract Design Apixaban is a direct oral anticoagulant that inhibits factor Xa. Our objective was to examine the effect of apixaban on perioperative transfusion requirements in pediatric patients undergoing cardiac..

Perfusfind S.L.

Abstract The transfusion of ABO compatible but not ABO identical red blood cells and plasma and the transfusion of platelets and cryoprecipitate without concern for ABO in any manner, are..

Perfusfind S.L.

Abstract Background and Objectives Red blood cells are often overprepared for surgery, leading to waste and increased costs, despite the need for cross-matching tests. This study aimed to develop a..

Perfusfind S.L.

Abstract Red blood cells (RBCs) play a crucial role in delivering oxygen to tissues with their distinctive shape. However, the mechanisms underlying cellular deformation and rupture due to stress, which..

Perfusfind S.L.

Abstract Background ECMO-associated coagulopathy is a common phenomenon in patients undergoing ECMO therapy. However, data on coagulation trajectories in the post ECMO decannulation period are limited. This study aimed to..

Perfusfind S.L.

Abstract Shear-induced platelet activation and receptor shedding in mechanical circulatory support (MCS) paradoxically increase risks of thrombosis and bleeding. Although flow cytometry commonly assesses platelet activation and receptor expression, correlations..

Perfusfind S.L.

Abstract Background The microaxial flow pump (mAFP) has demonstrated improved outcomes in selected patients with ST-segment elevation acute myocardial infarction and cardiogenic shock (STEMI-CS). However, its use has been associated..

Perfusfind S.L.

Abstract Aim Erythrocytes from patients with thalassemia might be susceptible to hemolysis during recycling and washing. Therefore, autologous erythrocyte transfusion using erythrocytes from parturient women with thalassemia has been suggested..

Perfusfind S.L.

Abstract A previously well 23-year-old man presented to the Trauma Department of a large urban Level 1 Trauma Centre in South Africa. The patient sustained a stab wound to the..

Perfusfind S.L.

Abstract Objectives:  This study aims to compare intraoperative blood transfusion and perioperative outcomes for patients undergoing left ventricular assist device (LVAD) implantation before and after the implementation of a blood..

Perfusfind S.L.

Abstract Background Hemogram is a novel biodegradable powdered hemostatic agent developed by binding calcium ions (Ca²+) to carboxymethyl starch (CM-starch) and applying granulation technology to enhance blood absorption and hemostatic..

Perfusfind S.L.

Abstract Postoperative thrombocytopenia (TP) is a serious complication of cardiopulmonary bypass (CPB). An accurate prediction model is crucial for the early identification of high-risk patients. This study aimed to develop..

Perfusfind S.L.

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR), an emerging resuscitative therapy following refractory cardiac arrests, is associated with hemorrhagic complications that potentially affect patient outcomes. Objectives This study evaluated the risks..

Perfusfind S.L.

Abstract Objective This scoping review systematically examines the use of intraoperative cell salvage in bacterially contaminated surgical settings, examining contamination levels, decontamination strategies, and clinical outcomes following the reinfusion of..

Perfusfind S.L.

Abstract Background Up to half of patients with infective endocarditis (IE) require cardiac surgery. Although anaemia is common, its precise prevalence, transfusion practices and impact on outcomes in surgically treated IE..

Perfusfind S.L.

Abstract Objectives CytoSorb, an extracorporeal blood purification device composed of biocompatible, highly porous polymer beads, is being increasingly adopted in different critically ill settings to allow for both enhanced organ..

Perfusfind S.L.

Abstract Background: Postoperative thrombocytopenia is a frequent finding after cardiac surgery, affecting approximately 10–40% of patients. The early decline in platelet count, typically observed within the first 48–72 h, is..

Perfusfind S.L.

Abstract Objective: The global shortage of blood resources has become a significant concern. This study aimed to assess the effects and feasibility of preoperative autologous blood donation (PABD) in elective..

Perfusfind S.L.

Abstract There are three reasons why perfusionists and autotransfusionists around the globe still use Normal Saline with cell savers; (1) This what they were taught by their peers and/or didactic..

Perfusfind S.L.

Abstract Cold-stored platelets were abandoned in the 1960s after demonstration of an increased clearance in vivo due to an irreversible activated phenotype. Difficulties in storage, logistics, and the increased requirement..

Perfusfind S.L.

Abstract  Objective: To compare the effects of intraoperative cell salvage (ICS) and preoperative autologous blood donation (PABD) on postoperative coagulation and platelet function in patients undergoing cardiac surgery, and to..

Perfusfind S.L.

Abstract Importance  Platelet transfusion is critical in managing major bleeding, but access to liquid-stored platelets is limited by their 5- to 7-day shelf life. Cryopreserved platelets last up to 2 years..

Perfusfind S.L.

Abstract Background Coronary artery bypass grafting (CABG) carries a high risk of bleeding and allogeneic blood transfusions, both associated with poor outcomes. We assessed perioperative transfusions and factors associated with..

Perfusfind S.L.

Abstract Purpose: Cryoprecipitate has been covered by Japanese national health insurance since 2020 for cardiopulmonary bypass (CPB)-induced hypofibrinogenemia. This study evaluated the clinical efficacy of in-house cryoprecipitate use in patients..

Perfusfind S.L.

Abstract Background Postoperative bleeding is a major concern in cardiac surgery, often leading to significant transfusion requirements. Despite this high transfusion demand, the use of postoperative autologous blood transfusion (PABT)..

Perfusfind S.L.

Abstract Cancer surgery accounts for a substantial proportion of allogeneic blood use. As demographic changes lead to a growing number of oncologic procedures, transfusion demands are increasing, while blood supply..

Perfusfind S.L.

Abstract Heart transplantation (HT) is the definitive therapy for end-stage heart failure. Patients unwilling to receive blood product transfusions are often considered ineligible for HT due to the significant perioperative..

Perfusfind S.L.

Abstract Objectives Bleeding is a common complication of extracorporeal membrane oxygenation (ECMO) support. While chest tube treatment is infrequently linked to bleeding in non-ECMO patients, several reports suggest a markedly..

Perfusfind S.L.

Abstract Background Fibrinogen concentrate may reduce allogeneic blood product transfusion in cardiac surgery patients with bleeding associated with acquired hypofibrinogenemia. The European Society of Anaesthesiology and Intensive Care (ESAIC) has..