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Vasoplegic syndrome and its treatment with vasopressin during cardiac surgery with cardiopulmonary bypass

Abstract Cardiac surgery with cardiopulmonary bypass is associated with systemic inflammatory response. In some cases this clinical condition is characterized by severe hypotension due to low systemic vascular resistance during..

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Cirugía cardiaca con circulación extracorpórea: síndrome vasoplégico y vasopresina

La cirugía cardiaca con circulación extracorpórea (CEC) se acompaña de una respuesta inflamatoria sistémica, caracterizada por vasodilatación y por disminución de la resistencia vascular sistémica (RVS). Esta condición patológica se..

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Efecto de la circulación extracorpórea sobre la perfusión microvascular en pacientes sometidos a cirugía cardíaca.

RESUMEN  La vía final común de los efectos de la circulación extracorpórea es la hipoperfusión periférica, que se valora indirectamente a través de la utilización de O2 en la periferia. El Orthogonal..

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Lesiones neurológicas durante la circulación extracorpórea: fisiopatología, monitorización y protección neurológica

RESUMEN La incidencia de lesiones neurológicas graves tras la cirugía cardíaca se ha establecido en un 6,1%: un 3,1% de lesiones focales y un 3% de lesiones difusas. Parece que..

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¿Qué es la Circulación Extracorpórea?

¿Qué es una bomba de circulación extracorpórea? Gran parte de los procedimientos de Cirugía Cardiaca se realizan mediante “Circulación extracorpórea”, técnica que, aunque ya tiene unas cuantas décadas, es fundamental..

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Circulación extracorpórea en la cirugía de la aorta

RESUMEN La perfusión en la enfermedad patología sigue siendo un gran reto. Los constantes cambios que se han producido en la canulación, han producido como consecuencia la modificación del sentido..

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Adherence to blood product transfusion guidelines—An observational study of the current transfusion practice in a medical intensive care unit

Abstract Background Blood transfusions though life‐saving are not entirely benign. They are the most overused procedure in the hospital and have been under scrutiny by the ‘Choosing Wisely campaign’. The..

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Usefulness of Self-Expanding Drainage Cannula in Venovenous Extracorporeal Membrane Oxygenation

Abstract Inadequate venous drainage decreases the efficiency of extracorporeal membrane oxygenation (ECMO). Pump augmentation may even make it worse due to collapse of the venous system under negative pressures. Furthermore, recirculation is..

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Early Decompressive Laparotomy for Intra-Abdominal Hypertension Following Initiation of Venovenous Extracorporeal Membrane Oxygenation

Abstract Patients supported with venovenous extracorporeal membrane oxygenation are at risk for intra-abdominal hypertension and abdominal compartment syndrome. Flow through the return cannula may be compromised in these patients, resulting..

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Recirculation in Venovenous Extracorporeal Membrane Oxygenation

Abstract Recirculation, a phenomenon in which reinfused oxygenated blood is withdrawn by the drainage cannula without passing through the systemic circulation, decreases the efficiency with which venovenous extracorporeal membrane oxygenation..

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Physiologic Basis for Venovenous Extracorporeal Membrane Oxygenation Management

Abstract To the Editor: Tay et al provide an excellent overview on the practical management of venovenous extracorporeal membrane oxygenation (VV-ECMO). The physiologic basis for the proposed algorithms should be discussed..

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World-first paediatric heart transplant technique boosts number of life-saving operations for children in the UK

Abstract Great Ormond Street Hospital (GOSH) and Royal Papworth Hospital (RPH) have collaborated to introduce a world-first paediatric heart transplant technique that has successfully expanded the donor pool and increased..

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Can Peroperative Neutrophil To Lymphocyte Ratio Change (Deltanlr) Be Used as a Parameter in Predicting Acute Renal Failure Following Coronary…

Abstract Background:  Inflammation plays a significant role in the pathogenesis of many diseases as well as postoperative acute renal failure (ARF). Preoperative neutrophil to lymphocyte ratio (NLR) values have a..

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Acute Response of Human Aortic Endothelial Cells to Loss of Pulsatility as Seen during Cardiopulmonary Bypass

Abstract Cardiopulmonary bypass (CPB) results in short-term (3–5 h) exposure to flow with diminished pulsatility often referred to as “continuous flow”. It is unclear if short-term exposure to continuous flow..

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Unconscious (Implicit) Bias

Abstract Recognition, acknowledgment, and acceptance of biases in a nonjudgmental manner is key to advancing knowledge and avoiding biased behaviors. Unconscious biases do not mean people are bad, and they..

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The association between intraoperative cell salvage and red blood cell transfusion in cardiac surgery – an observational study in a…

Abstract Cardiac surgery is commonly associated with high blood loss and the need for allogeneic red blood cell (RBC) transfusion. In addition, 20–30% of cardiac surgical patients suffer from anaemia..

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Cardiac Biomarkers for Risk Stratification of Acute Kidney Injury After Pediatric Cardiac Surgery

Abstract Background Children undergoing a cardiac surgical procedure are at increased risk for acute kidney injury (AKI). Novel biomarkers are needed to improve risk stratification of AKI after cardiac surgery...

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Prepump autologous blood collection is associated with reduced intraoperative transfusions in aortic surgery with circulatory arrest: A propensity score-matched analysis

Abstract Objective To evaluate the effect of autologous whole blood (AWB) collection on intraoperative/postoperative allogeneic blood transfusion rate in complex aortic surgery with hypothermic circulatory arrest. Methods This retrospective study..

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Vasopressor Therapy in Cardiac Surgery—An Experts’ Consensus Statement

Abstract Hemodynamic conditions with reduced  commonly are observed in patients undergoing cardiac surgery and may range from moderate reductions in , as a side effect of general anesthetics, to a profound vasodilatory..

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Dual veno-arterial extra-corporeal membrane oxygenation support in a patient with refractory hyperdynamic septic shock: a case report

Abstract The hypodynamic septic shock appears to be a promising indication to veno-arterial membrane oxygenation (VA-ECMO) support of a patient with insufficient cardiac output. With cardiac recovery most of those..

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A Computational Fluid Dynamics Study of the Extracorporeal Membrane Oxygenation-Failing Heart Circulation

Abstract Extracorporeal membrane oxygenation (ECMO) is increasingly deployed to provide percutaneous mechanical circulatory support despite incomplete understanding of its complex interactions with the failing heart and its effects on hemodynamics and perfusion...

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The diagnostic accuracy of procalcitonin in infectious patients after cardiac surgery: a systematic review and meta-analysis

Abstract Cardiac surgery with cardiopulmonary bypass (CPB) induces an acute inflammatory response that may lead to a systemic inflammatory response syndrome. The interest in procalcitonin (PCT) in the diagnosis of..

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Anticoagulation and Transfusion Management During Neonatal and Pediatric Extracorporeal Membrane Oxygenation

Abstract Objectives:  To compare current practices within the United States of anticoagulation management and blood transfusion in neonatal and pediatric extracorporeal membrane oxygenation patients with a 2013 international report. Design: ..

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Point-of-Care Platelet Function Monitoring: Implications for Patients With Platelet Inhibitors in Cardiac Surgery

Abstract Although most physicians are comfortable managing the limited  effect of aspirin, the recent administration of potent P2Y12 receptor inhibitors in patients undergoing cardiac surgery remains a dilemma. Guidelines recommend discontinuation of..

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Peer-review of “A history of cardiac surgery: an adventurous voyage from antiquity to the artificial heart” by Ugo Filippo Tesler

Abstract The storytelling of contemporary cardiac surgery is narrated from early extra cardiac procedures to open heart surgery. The Italian author, Dr. Tesler, has been a testimonial of any step...

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Cardiopulmonary Bypass Suppresses Forkhead Box O3 and Downstream Autophagy in the Diabetic Human Heart

Abstract Background Autophagy is an integral component of cellular  and metabolism. The exact mechanism of impaired autophagy in diabetes mellitus is unknown. Forkhead Box O3 (FOXO3α) is a key regulator of..

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Balancing the Blood Component Transfusion Ratio for High- and Ultra High–Dose Cell Salvage Cases

Abstract Objective To assess the ratio of non-red blood cell to red blood cell components required to avoid coagulopathy when transfusing large amounts of salvaged blood using laboratory test–guided therapy...

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Collateral flow at circle of Willis in healthy condition

Abstract Experimental simulation of cerebrovascular system would be very beneficial tool to evaluate millions of human body cascade sequence. The Circle of Willis (CoW) recently named Cerebral Arterial Circle (CAC)..

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Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries

Abstract Importance  Tracheal intubation is one of the most commonly performed and high-risk interventions in critically ill patients. Limited information is available on adverse peri-intubation events. Objective  To evaluate the incidence and..

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Respiratory and Hemodynamic Effects of Prophylactic Alveolar Recruitment During Liver Transplant: A Randomized Controlled Trial.

Abstract Objectives Prolonged surgical retraction may cause atelectasis. We aimed to recruit collapsed alveoli, stepwise, monitored by lung dynamic compliance and observe effects on arterial oxygenation and systemic and graft..

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