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Intraoperative Hypotension–Physiologic Basis and Future Directions

Abstract Intraoperative hypotension (IOH) is a major concern to the anesthesiologist. Its appropriate identification and management require an understanding of the physiology of blood pressure regulation, prudent blood pressure monitoring,..

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First Transcatheter TricValve System Implanted for Tricuspid Regurgitation in North America

Abstract In February 2022, Cleveland Clinic interventional cardiologists performed the first implantation of the TricValve® Transcatheter Bicaval Valves System in a patient in North America. The successful case, completed in an..

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Imaging the acute respiratory distress syndrome: past, present and future

Abstract In patients with the acute respiratory distress syndrome (ARDS), lung imaging is a fundamental tool in the study of the morphological and mechanistic features of the lungs. Chest computed..

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Reliability of the Minto model for target-controlled infusion of remifentanil during cardiac surgery with cardiopulmonary bypass

Abstract Background The Minto pharmacokinetic model is used for target-controlled infusion of remifentanil. The reliability of this model has never been evaluated during normothermic cardiac surgery with cardiopulmonary bypass (CPB)...

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Deliberate practices of speaking up and responding skills: the Speak-PREP e-learning module for healthcare professionals

Abstract Purpose Speaking up and responding to others’ concerns promotes patient safety. We describe health professionals’ utilisation of these important skills. Method We developed an interactive e-learning module, Speak-PREP, to train healthcare..

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Veno-arterial extracorporeal membrane oxygenation without allogeneic blood transfusion: An observational cohort study

Abstract Introduction It remains unclear whether patients who will not accept allogeneic blood transfusion can be managed successfully with veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO). The objective of our study..

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Cardiac Arrest, E-CPR, & Post-Arrest Care with Dr. Jason Bartos

Abstract Approximately 350,000 adults per year in the US experienced out-of-hospital cardiac arrest (OHCA). Only about 10% of such patients survive their initial hospitalization. The key drivers of successful resuscitation..

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Single-Dose St. Thomas Versus Custodiol® Cardioplegia for Right Mini-thoracotomy Mitral Valve Surgery

Abstract Objective Custodiol® and St. Thomas cardioplegia are widely employed in mini-thoracotomy mitral valve (MV) operations. One-dose of the former provides 3 h of myocardial protection. Conversely, St. Thomas solution is..

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Nosocomial infections during extracorporeal membrane oxygenation

Abstract Purpose of the review  The aim of this review is to present the latest evidence regarding the prevention, diagnosis and treatment of nosocomial infections during extracorporeal membrane oxygenation (ECMO)..

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Central venous pressure (CVP)

Abstract Until recently, the central venous pressure (CVP) was the preferred variable to guide fluid therapy [1]. The interest for CVP has declined in the last few years, mainly after..

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Head and thorax elevation prevents the rise of intracranial pressure during extracorporeal resuscitation in swine

Abstract Aim  Head and thorax elevation during cardio-pulmonary resuscitation improves cerebral hemodynamics and ultimate neurological outcome after cardiac arrest. Its effect during extracorporeal cardiopulmonary resuscitation (E-CPR) is unknown. We tested..

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Respiratory indications for ECMO: focus on COVID‑19

Abstract Extracorporeal membrane oxygenation (ECMO) is increasingly being used for patients with severe respiratory failure and has received particular attention during the coronavirus disease 2019 (COVID-19) pandemic. Evidence from two..

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Mortality and cost of post-cardiotomy extracorporeal support in the United States

Abstract Background Extracorporeal membrane oxygenation (ECMO) has been used increasingly for cardiopulmonary rescue. Despite recent advances however, post-cardiotomy shock (PCS)-ECMO survival remains comparatively poor. We sought to evaluate outcomes and..

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Patient-centered weaning from venoarterial extracorporeal membrane oxygenation: “A practice-oriented narrative review of literature”

Abstract Venoarterial extracorporeal membrane oxygenation (V-A ECMO) is increasingly used in cardiogenic shock for rapid stabilization and bridging towards recovery, long-term mechanical circulatory support or transplant. Although technological advances have..

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How to Do It: A Safe Bedside Protocol for Dual-Lumen Right Internal Jugular Cannulation for Venovenous Extracorporeal Membrane Oxygenation in…

Abstract In appropriately selected patients with COVID-19 acute respiratory distress syndrome, venovenous extracorporeal membrane oxygenation (VV ECMO) may offer a promising bridge to lung recovery or lung transplantation if lung recovery..

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Everything you need to know about deresuscitation

Why deresuscitation? While fluid administration is one of the most common therapeutic interventions in critical care, it carries high potential for harm as overzealous fluid resuscitation may lead to glycocalix..

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Development of a Standardized Assessment of Simulation-based Extracorporeal Membrane Oxygenation Educational Courses

Abstract Background In 2020, the Extracorporeal Life Support Organization education task force identified seven extracorporeal membrane oxygenation (ECMO) educational domains that would benefit from international collaborative efforts. These included research..

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Role of extracorporeal membrane oxygenation and surgical embolectomy in acute pulmonary embolism

Abstract Purpose of review  Surgery is an important option to consider in patients with massive and submassive pulmonary emboli. Earlier intervention, better patient selection, improved surgical techniques and the use of..

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Mitral Valve Dysfunction in Patients With Annular Calcification

Abstract Various anticoagulant properties have been associated with hydroxyethyl starch (HES). However, the mechanism remains unclear and it has not been fully considered whether these properties are beyond the dilutional..

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Protective ventilation

Abstract Following the initial observation in animal models as early as 1967, a key paper in 1974 demonstrating that high inspiratory pressures caused lung injury [] (Fig. ), crystallized the recognition..

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Advancements of DragonHeart BiVentricular Assist Device

Abstract Purpose of Study: Availability of mechanical circulatory support of both sides of the heart for pediatric patients has been limited due to size constraints. By combining 2 scaled down ventricular..

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En Bomba Vol. 6 Núm. 1 (2022) ; revista Asociación Latinoamericana de perfusión.

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Metabolomic profiling demonstrates evidence for kidney and urine metabolic dysregulation in a piglet model of cardiac surgery-induced acute kidney injury

Abstract Acute kidney injury (AKI) is a common cause of morbidity after congenital heart disease surgery. Progress on diagnosis and therapy remains limited, however, in part due to poor mechanistic..

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Intraoperative hemoadsorption in high-risk patients with infective endocarditis

Abstract Background Postoperative sepsis is an important cause of morbidity and mortality in patients with infective endocarditis undergoing surgical therapy. Blood purification using hemoadsorption therapy shows promising results in the..

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Thrombosis in Extracorporeal Membrane Oxygenation (ECMO) Circuits

Abstract Thrombosis in extracorporeal membrane oxygenation (ECMO) circuits remains a frequent complication. We characterize the location, extent, structure, and clinical implications of thrombi in 53 ECMO circuits from 46 pediatric patients...

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Cannulas and Cannulation Options for Minimally Invasive Surgery

Abstract Traditionally, cardiac surgery has been practiced primarily through a median sternotomy; however, as instrumentation and experience continue to advance at exponential rates, the field of minimally invasive cardiac surgery..

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A prospective observational study on the effect of emboli exposure on cerebral autoregulation in cardiac surgery requiring cardiopulmonary bypass

Abstract Objective: Cerebrovascular autoregulation impairment has been associated with stroke risk in cardiac surgery. We hypothesized that greater arterial emboli exposure in open-chamber surgery might promote dysautoreguation. Methods: Forty patients..

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Key characteristics impacting survival of COVID-19 extracorporeal membrane oxygenation

Abstract Background Severe COVID-19 induced acute respiratory distress syndrome (ARDS) often requires extracorporeal membrane oxygenation (ECMO). Recent German health insurance data revealed low ICU survival rates. Patient characteristics and experience..

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Effect of Intraoperative Handovers of Anesthesia Care on Mortality, Readmission, or Postoperative Complications Among Adults

Abstract Importance  Intraoperative handovers of anesthesia care are common. Handovers might improve care by reducing physician fatigue, but there is also an inherent risk of losing critical information. Large observational analyses..

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The Predictive Value of the 4Ts and HEP Score at Recommended Cutoffs in Patients With Mechanical Circulatory Support Devices

Abstract Objectives Despite the increasing utilization of mechanical circulatory support (MCS) devices, the 4Ts and heparin-induced thrombocytopenia (HIT) Expert Probability (HEP) scores have not been validated in patients with suspected..

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