Abstract Objectives To evaluate the analgesic and anti-haemorrhagic efficacy of platelet-rich plasma (PRP) among patients undergoing tonsillectomy. Design A systematic review and meta-analysis of randomised controlled trials (RCTs). Setting PubMed,..
Read MoreAbstract Introduction Hyperlactatemia, a problem reported in up to 30% of cardiac surgery patients, results from excessive production of or decreased clearance of lactate. It is typically a symptom of..
Read MoreManaging a team in the operating room: The science of teamwork and non-technical skills for surgeons
Abstract At 3:15 AM on an otherwise unremarkable Thursday morning, a routine appendectomy was about to begin. Well, at least everyone thought it would be routine. Nothing about the 22-year-old..
Read MoreAbstract Over the last several years, the use of extracorporeal membrane oxygenation (ECMO) has exponentially increased. As the technology advanced, the rate of devastating complications has decreased somewhat, and the..
Read MoreAbstract Background Clinical trials inform on average efficacy, but individualized risk assessments for outcome prediction are important in guiding treatment implementation. Objectives The authors developed and validated a patient-specific risk..
Read MoreAbstract Purpose Dual-lumen (ECMO) is considered technically challenging and harbors the risk of potential life-threatening complications during cannulation. Dual-lumen insertion is performed under either ultrasound or guidance. Both techniques have significant disadvantages, such as..
Read MoreAbstract Background Undergoing cardiac surgery often result in perioperative loss of health-related quality of life (HRQOL). Although participation rates in Australia is low, cardiac rehabilitation (CR) has been demonstrated to..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) has become an important therapeutic approach in the COVID-19 pandemic. The development and research in this field strongly relies on animal models; however, efforts are..
Read MoreAbstract BACKGROUND A recent prospective study reported a decrease in postoperative mortality when cardiac surgery was started in the afternoon instead of in the morning. In contrast, several large retrospective..
Read MoreAbstract Academic medical centers have a duty to serve as hospitals of last resort for advanced cardiac surgical care and therefore manage patients at elevated risk of postoperative morbidity and..
Read MoreAbstract Background: Preventable surgical errors of varying degrees of physical, emotional, and financial harm account for a significant number of adverse events. These errors are frequently tied to systemic problems..
Read MoreAbstract The provision of cardiac surgery services nationwide has been affected by the COVID-19 pandemic. We noticed a high COVID-19 mortality rate in unvaccinated patients who were diagnosed with COVID-19..
Read MoreMachine Learning to Predict Outcomes and Cost by Phase of Care After Coronary Artery Bypass Grafting
Abstract Background Machine learning may enhance prediction of outcomes after (CABG). We sought to develop and validate a dynamic machine learning model to predict CABG outcomes at clinically relevant pre- and..
Read MoreAbstract Background: Patients on direct oral anticoagulants are at high risk of perioperative bleeding complicaapitions. We analyzed the results of intraoperative hemoadsorption (HA) in patients undergoing cardiac surgery who were..
Read MoreAbstract Background Shock severity predicts mortality in patients with cardiogenic shock (CS). We evaluated the association between pre-cannulation Society for Cardiovascular Angiography and Interventions (SCAI) shock classification and mortality among..
Read MoreAbstract Background Minimally invasive extracorporeal circulation (MiECC) is employed as a strategy to attenuate the physiologic disturbance caused by cardiopulmonary bypass. The aim of this study was to compare the..
Read MoreAbstract During a 6 week period beginning early March 2020, 30 patients with severe coronavirus disease 2019 (COVID-19) were supported with venovenous extracorporeal membrane oxygenation (ECMO). This volume increase mandated..
Read MoreAbstract Background Treatment of significant coagulopathic cardiac surgical field bleeding with immediate higher-dose (PCC) without (FFP) or is unexplored. Aims To study characteristics, , and clinical outcomes of patients with significant coagulopathic surgical field..
Read MoreAbstract The implantation of the left ventricular assist device Abbott HeartMate 3TM is being increasingly performed for management of end-stage heart failure. LVAD implantation might be associated with early or..
Read MoreAbstract Mitral valve prolapse (MVP) is the most common primary valvular abnormality, associated with various degrees of incompetent function and sequelae, including heart failure and sudden cardiac death. Recent improvements..
Read MoreAbstract Background: This study aimed to estimate the cost-effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for in-hospital cardiac arrest treatment. Methods: A decision tree and Markov model were constructed based on current literature...
Read MoreAbstract Left ventricular assist devices (LVADs) are safer and provide better survival and better quality of life than biventricular assist devices (BVADs) but end-stage heart failure often involves both ventricles,..
Read MoreAbstract We describe three successful cases of HeartMate left ventricular assist device (LVAD; Thermo Cardiosystems, Woburn, MA, USA) implantation in patients with end-stage heart failure for long-term circulatory support. Patient..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is a treatment that provides hemodynamic or respiratory support to severely critically ill patients. However, ECMO introduces many variables that must be considered for antibiotic..
Read MoreAbstract Out-of-hospital cardiac arrest is a leading cause of mortality with survival rates of less than 10%. In selected patients, survival may be improved via timely application of extracorporeal cardiopulmonary resuscitation (ECPR)...
Read MoreAbstract Introduction Lactate levels have been recognized as a reliable tool for monitoring critically ill patients requiring venoarterial extracorporeal membrane oxygenation (VA ECMO) or venovenous extracorporeal membrane oxygenation (VV ECMO)..
Read MoreAbstract BACKGROUND: Perioperative hemodynamic instability mediated by anaphylaxis is a life-threatening complication in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). This study aimed to evaluate the effect of clemastine fumarate..
Read MoreAbstract Clinical presentation and mortality of patients treated with extracorporeal membrane oxygenation (ECMO) for COVID-19 acute respiratory distress syndrome (CARDS) were different during the French epidemic waves. The management of..
Read MoreAbstract Background: Extracorporeal membrane oxygenation (ECMO) is widely utilized for severe cardiopulmonary insufficiency, but its application to the oncologic population has been debated given concern for increased risk of infection. This..
Read MoreAbstract Aim To evaluate the ability of the DrugSorb™-AntiThrombotic Removal (ATR) haemoadsorption device utilizing porous polymer bead sorbent technology to remove three commonly used antithrombotic drugs from whole blood. Methods..
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