In February 2022, Cleveland Clinic interventional cardiologists performed the first implantation of the TricValve^® Transcatheter Bicaval Valves System in a patient in North America. The successful case, completed in an 82-year-old man with severe symptomatic tricuspid regurgitation (TR) and right heart failure (RHF), was carried out under a compassionate-use clearance from the FDA.