Abstract Background Postoperative pulmonary complications increase mortality after cardiac surgery. Conventional ultrafiltration may reduce pulmonary complications by removing mediators of bypass-induced inflammation and countering hemodilution. We tested the primary hypothesis..
Read MoreAbstract Acute kidney injury (AKI) is a frequent complication of cardiac surgery that contributes to postoperative morbidity and mortality. The timing of renal replacement therapy (RRT) remains unclear. The Artificial..
Read MoreAbstract Many young adults require heart valve replacements. Current options for valve replacement in adults include mechanical valves, bioprosthetic valves, or the Ross procedure. Of these, mechanical and bioprosthetic valves..
Read MoreAbstract Background Refractory out-of-hospital cardiac arrest (OHCA) treated with standard advanced cardiac life support (ACLS) has poor outcomes. Transport to hospital followed by in-hospital extracorporeal cardiopulmonary resuscitation (ECPR) initiation may..
Read MoreAbstract Interhospital transport of acute respiratory distress syndrome (ARDS) patients bears transport-associated risks. It is unknown how interhospital extracorporeal membrane oxygenation (ECMO) transfer of COVID-19 patients by mobile ECMO units affects ARDS mortality. We compared the outcome..
Read MoreAbstract Venlafaxine is a serotonin and noradrenalin reuptake inhibitor prescribed as an antidepressant. Overdose clinically manifests with neurological, cardiovascular and gastrointestinal abnormalities based on, amongst others, serotonin syndrome and can..
Read MoreAbstract Membrane oxygenator failure during venovenous (V-V) extracorporeal membrane oxygenation (ECMO) can lead to life-threatening hypoxia, high replacement costs, and may be associated with a hyperfibrinolytic state and bleeding. The current understanding..
Read MoreAbstract Refractory right ventricular failure has significant morbidity and mortality. Extracorporeal membrane oxygenation is indicated when medical interventions are deemed ineffective. However, it is still being determined if one configuration is better. We conducted..
Read MoreAbstract Background Valve reintervention after transcatheter aortic valve replacement (TAVR) failure has not been studied in detail. Objectives The authors sought to determine outcomes of TAVR surgical explantation (TAVR-explant)..
Read MoreAbstract Background Anaemia and blood transfusion are two independent contributing factors to perioperative morbidity in cardiac surgery. While preoperative treatment of anaemia has been shown to improve outcomes, in real..
Read MoreAbstract Introduction Off-pump coronary artery bypass grafting (OPCABG) was introduced many years ago aiming to reduce the known complications of conventional on-pump coronary surgeries. Heparin is required during the procedures,..
Read MoreAbstract OBJECTIVES Minimally invasive mitral valve surgery (MIMVS) has evolved over the last 2 decades. The aim of the study was to identify the impact of era and technical improvements..
Read MoreAbstract Background: Neurocognitive decline (NCD) is a common complication of cardiac surgery. Understanding risk factors helps surgeons counsel patients pre- and peri-operatively about risk, prevention, and treatment. Results: Eighty-four patients undergoing cardiac surgery utilizing..
Read MoreHigh- versus Low-Flow Extracorporeal Respiratory Support in Experimental Hypoxemic Acute Lung Injury
Abstract Rationale: In the EOLIA (ECMO to Rescue Lung Injury in Severe ARDS) trial, oxygenation was similar between intervention and conventional groups, whereas V˙V˙e was reduced in the intervention group. Comparable reductions in..
Read MoreAbstract Objective Packed during is known to be associated with . However, the association of the timing between transfusions in relation to discharge and 30-day postoperative outcomes has not been studied. The study..
Read MoreAbstract Objectives: Cardiopulmonary bypass (CPB) induces inflammatory homeostasis dysregulation, closely related to many postoperative adverse effects. Minimizing the systemic inflammatory response to CPB is imperative to improving cardiac surgery safety...
Read MoreAbstract Congenital heart defect (CHD) surgeries are performed with cardiopulmonary bypass (CPB) and are complicated by several factors that affect the child’s brain. However, to date, the number of studies..
Read MoreAbstract Objective No recent prospective studies have analyzed the accuracy of standard coagulation tests and thromboelastography (TEG) to identify patients with excessive microvascular bleeding following cardiopulmonary bypass (CPB). The aim..
Read MoreAbstract There is little understanding about what proportion of the target audience have read guidelines published through the traditional approach. The COVID-19 pandemic created a particularly difficult scenario for healthcare..
Read MoreAbstract Objectives To compare the safety and efficacy of del-Nido cardioplegia (DNC) with traditional 4:1 cold blood cardioplegia (CBC) in coronary artery bypass grafting and/or valve surgeries in elderly patients...
Read MoreAbstract Inherited and acquired coagulopathy are frequently associated with major bleeding in severe trauma, cardiac surgery with cardiopulmonary bypass, and postpartum hemorrhage. Perioperative management is multifactorial and includes preoperative optimization..
Read MoreAbstract Background The high-quality evidence on managing COVID-19 patients requiring extracorporeal membrane oxygenation (ECMO) support is insufficient. Furthermore, there is little consensus on allocating ECMO resources when scarce. The paucity..
Read MoreAbstract Objectives The benefit of using gelatin solution in cardiac surgery is still controversial. Previous data suggested adverse interactions of gelatin infusion with (AKI) or . The purpose of this study was..
Read MoreAbstract Objective Cognitive impairment is a common neurologic complication after cardiac surgery with cardiopulmonary bypass (CPB). This study evaluated postoperative cognitive function to determine predictors of cognitive dysfunction, including intraoperative..
Read MoreAbstract Treatment recommendations for rewarming patients in severe accidental hypothermia with preserved spontaneous circulation have a weak evidence due to the absence of randomized clinical trials. We aimed to compare the outcomes..
Read MoreAbstract The aim of this experimantal study which is applied on rats, is to determine the differences on the clotting factors over the application of low and high intraabdominal pressure..
Read MoreAbstract Objective: The aim of this study was to describe decisions about the escalation and withdrawal of treatment for patients on extracorporeal membrane oxygenation (ECMO). Summary Background Data: Interventions premised..
Read MoreAbstract The identification of individuals at risk for acute aortic disease, by virtue of its silent pathogenesis, is vital for patient outcome. However, ineffective screening methods hamper the efforts of..
Read MoreAbstract Although uncommon, oxygenator thrombosis in extra-corporeal membrane oxygenation (ECMO) devicesremains a potential reason for exchanging the circuit,the risk of thrombosis increases with the duration ofECMO therapy and with procoagulant..
Read MoreAbstract Various cohort studies, both retrospective and prospective, showed that low antithrombin levels after cardiac surgery (at the arrival in the intensive care unit and during the next days) were..
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