Archives

Perfusfind S.L.

Abstract Background Optimal hemodynamic targets for preventing acute kidney injury (AKI) have remained elusive. We hypothesized that lower tissue perfusion pressure (TPP), a novel perfusion index representing the difference between..

Perfusfind S.L.

Abstract Traditionally, the diagnosis of kidney disease has relied primarily on serum creatinine (SCr). For acute kidney injury (AKI), changes in urine output (UO) have also been recognized as a..

Perfusfind S.L.

Abstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and important complication. The risk factors for CSA-AKI remain poorly described. We aimed to identify risk factors for CSA-AKI..

Perfusfind S.L.

Abstract Ex situ normothermic machine perfusion (NMP) of the liver has emerged as a dynamic preservation strategy, enabling the maintenance of metabolic activity and assessment of grafts prior to transplantation. Prolonged..

Perfusfind S.L.

Abstract Consistently high lactate levels and poor clearance on ECMO are important early signs of poor perfusion and useless care. For example, lactate levels over 8 mmol/L at 12 h, staying above..

Perfusfind S.L.

Abstract Objectives The Association of Cardiothoracic Anesthetists Perioperative Risk of Blood Transfusion (ACTA-PORT) score was originally developed to predict the need for transfusion in cardiac surgery patients. Given the inter-relationship..

Perfusfind S.L.

Abstract Cardiovascular surgery with cardiopulmonary bypass (CPB) is associated with several potential complications, including the activation of inflammatory and coagulation pathways, which may lead to acute kidney injury (AKI). In..

Perfusfind S.L.

Abstract Background:  Acute kidney injury (AKI) is a frequent complication of congenital heart surgery with cardiopulmonary bypass (CPB) in pediatric patients, contributing to significant morbidity and mortality. Aim:  To determine..

Perfusfind S.L.

Abstract Objective We aimed to develop and evaluate cardiac surgery–associated acute kidney injury (CSA-AKI) machine learning prediction models that included clinical variables, biomarkers, and high-frequency hemodynamic measurements. Design A prospective,..

Perfusfind S.L.

Abstract Acute kidney injury (AKI) affects 40–50% of cardiac surgery patients and is closely linked to renal medullary hypoxia. Although urinary oxygen partial pressure (PuO2) offers real-time insight into renal..

Perfusfind S.L.

Abstract Background This study aimed to develop a data-driven prediction model for cardiac surgery-associated acute kidney injury (CSA-AKI) at the end of surgery using machine learning (ML) algorithms. Methods We..

Perfusfind S.L.

Abstract Acute kidney injury (AKI) is a significant complication following cardiac surgery, affecting 20% to 30% of patients and contributing to increased morbidity and mortality. Cardiac surgery–associated AKI (CSA-AKI) is..

Perfusfind S.L.

Abstract Background Elevated central venous pressure during cardiac surgery can lead to increased renal venous pressure, subsequently resulting in renal insufficiency. However, there is a lack of animal models available..

Perfusfind S.L.

Abstract Perioperative acute kidney injury (AKI) is a frequent complication that affects outcomes well beyond the perioperative period. Its mechanisms remain incompletely understood, arising from the interplay of comorbidities, surgical..

Perfusfind S.L.

Abstract Objectives: This study aimed to assess whether continuous furosemide administration during cardiopulmonary bypass (CPB) in minimally invasive cardiac surgery (MICS) reduces the incidence of cardiac surgery-associated acute kidney injury..

Perfusfind S.L.

Abstract Background Acute renal impairment following cardiopulmonary bypass (CPB) is a serious perioperative complication with sustained occurrence. Proactive risk assessment and preventive strategies are crucial for enhancing surgical outcomes. Methods..

Perfusfind S.L.

Abstract Objectives:  To derive and externally validate supervised machine learning (ML) models predictive of cardiac surgery-associated acute kidney injury (CS-AKI). Design:  Retrospective cohort analysis. Setting:  Multicenter (4), cardiac surgical centers..

Perfusfind S.L.

Abstract Objectives To investigate the potential contribution of tissue oxygenation prediction in cardiac surgery–associated acute kidney injury (CSA-AKI) using near-infrared spectroscopy (NIRS) and serum lactate level measurements. Design A retrospective..

Perfusfind S.L.

Abstract Objectives Acute kidney injury (AKI) occurs in 19–42% of patients with cardiac surgery under cardiopulmonary bypass (CPB). Clarifying their landscape of immune cells may help discover the mechanisms and..

Perfusfind S.L.

Abstract This retrospective cohort study evaluates the validity of the Renal Angina Index (RAI) in predicting acute kidney injury (AKI) in 272 patients receiving extracorporeal membrane oxygenation (ECMO) support. The..

Perfusfind S.L.

Abstract Background Acute kidney injury (AKI) is a frequent complication following cardiac surgery involving cardiopulmonary bypass (CPB). This is partly attributable to crystalloid-based priming solutions causing both hemolysis and loss..

Perfusfind S.L.

Abstract Objectives Maintaining a nadir oxygen delivery ≥ 280 mL/min/m2 during cardiopulmonary bypass is a pillar of the goal-directed perfusion strategy in cardiac surgery. However, there are patients who develop a..

Perfusfind S.L.

Abstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is one of the most frequent and severe complications after cardiac surgery. The association between acute kidney injury and the mismatch between..

Perfusfind S.L.

Abstract Objectives Early prediction is crucial for cardiac surgery-associated acute kidney injury (CSA-AKI). We aimed to develop and validate a simple, clinical- and laboratory-based risk score system for better CSA-AKI..

Perfusfind S.L.

Abstract Cardiac procedures carry a higher perioperative risk than other operations for major adverse cardiovascular events and kidney injury, especially since patients with multiple comorbidities have been accepted as candidates..

Perfusfind S.L.

Abstract Purpose: Dexmedetomidine, an alpha-2 adrenergic agonist, has shown potential benefits in various surgical settings, but its impact on microcirculation and renal function in cardiac surgery patients remains unclear. Patients and..

Perfusfind S.L.

Abstract Objectives Oxygen delivery (DO2) is a pivotal factor in maintaining adequate tissue protection during cardiopulmonary bypass (CPB). Despite its clinical significance, there is currently no global consensus regarding standardized..

Perfusfind S.L.

Abstract Objective To determine the relationship between intraoperative decreased renal and cerebral oxygen saturation, as measured using near-infrared spectroscopy (NIRS), and cardiac surgery-associated acute kidney injury (CSA-AKI) in adults. Methods..

Perfusfind S.L.

Abstract Objectives: The difference between mean arterial pressure (MAP) before cardiopulmonary bypass (CPB) and mean perfusion pressure (MPP) during CPB is thought to be a strong predictor of acute kidney injury..

Perfusfind S.L.

Abstract Objectives Acute kidney injury (AKI) is a common and serious complication of cardiac surgery, often linked to the use and duration of cardiopulmonary bypass (CPB). The Hemolysis Index (HI)..