Perfusfind S.L.

Abstract Purpose To assess the effects of conventional ultrafiltration and conventional plus zero-balanced ultrafiltration on delirium and cognition in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods A total..

Perfusfind S.L.

Abstract Although the goal of extracorporeal cardiopulmonary resuscitation (ECPR) remains survival with meaningful neurologic recovery, secondary contribution to organ donation is increasingly recognized. We identified standardized outcome metrics for quality..

Perfusfind S.L.

Abstract Background Cardiac rhythm is a well-established prognostic factor in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR); however, existing evidence is primarily limited to small, single-center studies. This study aimed to..

Perfusfind S.L.

Abstract Severe respiratory failure is frequently complicated by right ventricular dysfunction (RVD), which occurs in 20–50% of cases. In patients on venovenous extracorporeal membrane oxygenation (VV ECMO) with refractory RVD,..

Perfusfind S.L.

Abstract Background: Unfractionated heparin (UFH) is the standard anticoagulant during cardiopulmonary bypass (CPB). A clinically relevant subset develops heparin resistance (HR)—failure to reach adequate anticoagulation with usual UFH—raising thrombotic risk..

Perfusfind S.L.

Abstract Infection is a common indication and complication for extracorporeal membrane oxygenation (ECMO), and adult ECMO recipients face increased nosocomial infection risk. Effective antimicrobial dosing in these patients remains difficult..

Perfusfind S.L.

Abstract Hyperoxia in pediatric cardiopulmonary bypass patients is associated with adverse effects, including reoxygenation injury, increased mortality, heightened inflammatory response, and cerebral injury. Although prior research has demonstrated a correlation..

Perfusfind S.L.

Abstract Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and cardiopulmonary bypass (CPB) are used during pediatric heart surgery to provide cardiopulmonary support to patients as they undergo and recover from surgical..

Perfusfind S.L.

Abstract Background:Infants with CHD who undergo cardiopulmonary bypass surgery are at risk of impaired growth and neurodevelopment. However, few studies have thoroughly investigated the risk factors for growth and neurodevelopmental..

Perfusfind S.L.

Abstract OBJECTIVES:  Vasoplegia is a common complication of cardiac surgery that uses cardiopulmonary bypass and contributes to morbidity and mortality, yet a consensus definition does not exist. The objective of..

Perfusfind S.L.

Abstract Cold-stored platelets were abandoned in the 1960s after demonstration of an increased clearance in vivo due to an irreversible activated phenotype. Difficulties in storage, logistics, and the increased requirement..

Perfusfind S.L.

Abstract Baseline cerebral regional oxygen saturation (rSO₂) measured with the INVOS 5100C near-infrared spectroscopy (NIRS) device has been reported to correlate primarily with preoperative B-type natriuretic peptide (BNP) and hemoglobin..

Perfusfind S.L.

Abstract  Objective: To compare the effects of intraoperative cell salvage (ICS) and preoperative autologous blood donation (PABD) on postoperative coagulation and platelet function in patients undergoing cardiac surgery, and to..

Perfusfind S.L.

Abstract Acute kidney injury (AKI) affects 40–50% of cardiac surgery patients and is closely linked to renal medullary hypoxia. Although urinary oxygen partial pressure (PuO2) offers real-time insight into renal..

Perfusfind S.L.

Abstract Background This study aimed to develop a data-driven prediction model for cardiac surgery-associated acute kidney injury (CSA-AKI) at the end of surgery using machine learning (ML) algorithms. Methods We..

Perfusfind S.L.

Abstract Background Simulation-based education (SBE) improves learner competence, patient safety and workforce readiness. Yet, existing frameworks such as INACSL and ASPiH provide limited guidance on developing sustainable, institution-wide strategies, particularly..

Perfusfind S.L.

Abstract Importance  Platelet transfusion is critical in managing major bleeding, but access to liquid-stored platelets is limited by their 5- to 7-day shelf life. Cryopreserved platelets last up to 2 years..

Perfusfind S.L.

Abstract Background Coronary artery bypass grafting (CABG) carries a high risk of bleeding and allogeneic blood transfusions, both associated with poor outcomes. We assessed perioperative transfusions and factors associated with..

Perfusfind S.L.

Abstract Optimized Extracorporeal Perfusion Strategy: A New Concept Early heart-lung machines were mechanically simple, with rudimentary monitoring capabilities, and caused pronounced physiological disturbances due to large priming volumes and uncoated..

Perfusfind S.L.

Abstract Pulmonary endarterectomy (PEA) remains the curative surgical option for chronic thromboembolic pulmonary hypertension (CTEPH), a condition requiring precise cardiopulmonary bypass (CPB) management to balance cerebral protection, myocardial preservation, and..

Perfusfind S.L.

Abstract Purpose: Cryoprecipitate has been covered by Japanese national health insurance since 2020 for cardiopulmonary bypass (CPB)-induced hypofibrinogenemia. This study evaluated the clinical efficacy of in-house cryoprecipitate use in patients..

Perfusfind S.L.

Abstract Background/Objectives: Whether a remote history of SARS-CoV-2 infection independently affects early haemodynamic stability after elective cardiopulmonary bypass (CPB) remains uncertain. We evaluated whether prior COVID-19 (>7 weeks before surgery)..

Perfusfind S.L.

Abstract Acute kidney injury (AKI) is a significant complication following cardiac surgery, affecting 20% to 30% of patients and contributing to increased morbidity and mortality. Cardiac surgery–associated AKI (CSA-AKI) is..

Perfusfind S.L.

Abstract Cardiac surgery poses specific challenges in fluid management. The role of albumin administration during cardiac surgery has long been controversial. Although it has theoretical advantages, it is expensive and..

Perfusfind S.L.

Abstract Background Elevated central venous pressure during cardiac surgery can lead to increased renal venous pressure, subsequently resulting in renal insufficiency. However, there is a lack of animal models available..

Perfusfind S.L.

Abstract This narrative review summarizes current evidence on the role of aminothiols as biomarkers of oxidative stress in patients undergoing coronary artery bypass grafting (CABG). CABG is accompanied by profound..

Perfusfind S.L.

Abstract Background Children with congenital heart disease are at risk for poor neurodevelopment. The gut microbiome may influence neurodevelopmental outcomes through the gut-brain axis. This study investigated the association of..

Perfusfind S.L.

Abstract Separation from cardiopulmonary bypass (CPB) is a critical phase of cardiac surgery, particularly in patients with pulmonary hypertension and right heart failure. Milrinone, a phosphodiesterase inhibitor, is often used..

Perfusfind S.L.

Abstract Introduction Vacuum-assisted venous drainage (VAVD) has been proposed as a better alternative option than conventional gravitational venous drainage (GVD) in cardiac surgery. However, the literature reports conflicting results between..

Perfusfind S.L.

Abstract Background Postoperative bleeding is a major concern in cardiac surgery, often leading to significant transfusion requirements. Despite this high transfusion demand, the use of postoperative autologous blood transfusion (PABT)..