Perfusfind S.L.
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Leukocytes in atrial fibrillation: mechanisms and therapeutics

Abstract Atrial fibrillation (AF) is a highly prevalent arrhythmia and a major cause of morbidity and mortality. Although AF is not a primarily immunologic disorder, increasing clinical, translational, and experimental..

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Resuscitative Transesophageal Echocardiography Simulation Based Education for Extracorporeal Cardiopulmonary Resuscitation Cannulation Guidance

Abstract Extracorporeal membrane oxygenation (ECMO) cannulation during refractory cardiac arrest has become a key therapeutic option in contemporary critical care medicine. When initiated in a timely manner, extracorporeal cardiopulmonary resuscitation..

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Mechanical circulatory support strategy in post–myocardial infarction ventricular septal defect repair

Abstract Post–myocardial infarction (PMI) ventricular septal defect (VSD) repair is associated with high mortality., The pathophysiology varies based on the size of the infarction and the VSD, which results in..

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A Novel Extracorporeal Membrane Oxygenation System With Enhanced Hemocompatibility and Long-Term Stability

Abstract To optimize and evaluate the hydrodynamic performance and gas exchange efficiency of a newly developed centrifugal blood pump and membrane oxygenator for extracorporeal membrane oxygenation (ECMO) support, blood pump..

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Mean arterial blood pressure during the first 24 hours after cardiac surgery and acute kidney injury: an observational cohort study

Abstract Objective(s): Mean arterial pressure (MAP) after cardiac surgery may contribute to acute kidney injury (AKI). We sought to identify threshold MAP values during the first 24 hours (h) postoperatively..

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REANIMATE 12 - Nov 18/19

Learn ECMO, ECPR, and Bleeding Edge Resuscitation A sim lab, a procedure lab, and one-on-one teaching so you can initiate ECMO and perform the most advanced hemodynamic resuscitation on your..

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Adult ECMO Simulation Course - April 12/15

This course is designed for learners who have completed the ELSO Virtual ECMO Training Course, ELSO Foundations: Adult ECMO Training Course, or for practitioners with a strong foundational knowledge of..

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Lactate and pH as Predictors of In-Hospital Mortality in Extracorporeal Cardiopulmonary Resuscitation: A Single-Center Retrospective Study

Abstract Objectives Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly employed for patients with refractory cardiac arrest, yet optimal criteria for patient selection remain poorly understood. Pre-cannulation lactate and pH values are..

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Platelets in Children: Physiological Function, Developmental Regulation, and Clinical Significance in Disease States

Abstract Platelets play a fundamental role in hemostasis; however, their phenotype, reactivity, and function vary across the pediatric age spectrum. While developmental differences in plasma coagulation proteins have been well-characterized..

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How to monitor and manage unfractionated heparin in practice (Part 1)? Guidance from the SSC of the ISTH

Abstract The International Society on Thrombosis and Haemostasis (ISTH) recently published a survey on the management of unfractionated heparin (UFH), which revealed substantial heterogeneity in practice and highlighted the need..

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Protecting the DCD lung: the importance of inmediate atrial decompression

      Dr.Sam Zeraatian Nejad Davani, Cardiovascular and Thoracic Surgeon, Transplant and Thoracic Organs Recovery Surgeon. Director of Georgia Atlanta Procure on Demand Thoracic Organs Transplant and Procurement Surgery. ..

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Venous first double TA-NRP in extended warm-ischemia DCD

    In Thoracoabdominal Normothermic Regional Perfusion (TA-NRP) for Donation after Circulatory Death (DCD), initiating central cannulation with a venous-first approach serves as a critical step to decompress an acutely..

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Early active normothermia versus no temperature control in a porcine model of extracorporeal cardiopulmonary resuscitation

Abstract Aim Early downward temperature drift is a common event of pre-hospital extracorporeal cardiopulmonary resuscitation (e-CPR), since prehospital extracorporeal membrane oxygenation (VA-ECMO) circuits often lack heat-exchangers. However, whether this core..

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Relative hematocrit declines at the time of transfusion and postoperative outcomes after coronary artery bypass grafting: a retrospective cohort study

Abstract Background Despite advances in patient blood management, the optimal hemoglobin threshold for Red Blood Cell (RBC) transfusion remains controversial. This observational study evaluated the association between the relative decline..

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Influence of microaxial flow pump level on haemolysis and kidney injury in patients with cardiogenic shock: a retrospective study

Abstract Aims Acute kidney injury (AKI) is common in patients treated with microaxial flow pumps (mAFP). Plasma-free haemoglobin (PFHb) due to haemolysis is known to increase kidney injury in a..

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Acute Kidney Injury After Cardiac Surgery in Low‑ and Middle‑Income Countries

Abstract Background: Cardiac‑surgery‑associated acute kidney injury (CSA‑AKI) is a frequent postoperative complication worldwide and is associated with increased mortality, prolonged intensive care unit stay, and substantial resource utilization. While reported..

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Early Decline in Serum Haptoglobin During Impella CP Support Compared With Intra‐Aortic Balloon Pump in Cardiogenic Shock: A Single‐Center Observational…

Abstract Background Hemolysis is a recognized complication of mechanical circulatory support and may contribute to acute kidney injury in patients with cardiogenic shock. Early hemolysis during Impella support, particularly compared..

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Considerations and future challenges in managing ECMO for pediatric patients

Abstract In managing ECMO, preventing thrombus formation and hemolysis is crucial. While centrifugal pumps are increasingly used in pediatric ECMO, pumps designed for low flow range are not approved in..

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Haematocrit During Cardiopulmonary Bypass and Risk for Acute Kidney Injury: An Observational Single-Centre Study

Abstract Objectives Low haematocrit during cardiopulmonary bypass is a known risk factor for acute kidney injury, but it is unclear whether high haematocrit also increases acute kidney injury risk. We..

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Re-evaluation of oxygenation and oxygen exposure in patients with ARDS and veno-venous extracorporeal membrane oxygenation

Abstract Optimal oxygen target levels for critically ill patients have been discussed for decades and very low but also high PaO2-levels were both associated with higher mortality [, ]. In..

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Anticoagulation Strategies for Cardiopulmonary Bypass in Heparin-Induced Thrombocytopenia: A Brief Review and Practical Algorithm

Abstract Heparin-induced thrombocytopenia (HIT) represents a high-risk perioperative challenge in patients undergoing cardiac surgery. Although unfractionated heparin remains the standard anticoagulant for cardiopulmonary bypass (CPB), its use in patients with..

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Liquid Lung Rest During Extracorporeal Life Support in a Neonatal Porcine Model of Acute Lung Injury

Abstract In patients with severe lung injury, extracorporeal life support (ECLS) enables lung rest, but the optimal strategy is unknown. This study compared liquid lung rest (LLR) versus standard gas rest ventilation..

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Nadir Oxygen Delivery During Pediatric Cardiopulmonary Bypass and Postoperative Acute Kidney Injury: A Pilot Cohort Study

Abstract Background: Among infants undergoing cardiac surgery, AKI may affect as many as 40% of this population and carries an unfavorable prognosis. A range of contributors has been implicated, including early..

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What is missing from fluid balance calculations during ECMO? Water loss from the membrane lung

Abstract Fluid administration and fluid balance are both important clinical considerations in the management of patients receiving extracorporeal membrane oxygenation (ECMO). Insufficient intravascular volume may limit the output of preload-dependent..

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Endoscopic Minimally Invasive Beating-Heart Tricuspid Valve Surgery Without Jugular Vein Cannulation or Caval Snaring: Clinical Outcomes Using Novel Percutaneous Venous…

Abstract Background and Objectives: Endoscopic beating-heart tricuspid valve (TV) surgery is increasingly adopted in cardiac surgery due to its association with improved postoperative recovery. Conventional approaches require jugular vein cannulation..

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Prosthetic valve thrombosis on venoarterial extracorporeal membrane oxygenation support: Risk factors and outcomes

Abstract Introduction In patients with prior valve replacement requiring venoarterial extracorporeal membrane oxygenation (VA ECMO), there is a risk of prosthetic valve thrombosis (PVT) due to intracardiac stasis. We describe..

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Bilateral radial arterial pressure concordance as a real-time bedside marker of native cardiac recovery during peripheral VA-ECMO weaning

Abstract Patients supported with peripheral femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO) frequently face the challenge of determining the optimal timing for weaning trials, as no universally standardized bedside method is..

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Rehabilitation Intensity and Discharge Outcomes in Venovenous Extracorporeal Membrane Oxygenation Used as a Bridge to Recovery

Abstract Early rehabilitation during venovenous extracorporeal membrane oxygenation used as a bridge to recovery (VV ECMO–BTR) may help preserve functional capacity. We retrospectively analyzed 153 adults supported with VV ECMO–BTR..

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Dapagliflozin and Acute Kidney Injury Following Cardiac Surgery

Abstract Importance  Two percent to 50% of patients undergoing elective cardiac surgery experience acute kidney injury (AKI) postoperatively. Medications to prevent AKI after elective cardiac surgery have not been identified. Objective  In..

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Lactate clearance and volume status at cannulation are associated with survival in trauma VV ECMO patients

Abstract Background Veno-venous extracorporeal membrane oxygenation (VV ECMO) is an advanced therapy for patients with respiratory failure refractory to conventional management. Volume overload and elevated lactate levels have been associated..

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