Perfusfind S.L.

Abstract Wound healing after myocardial infarction (MI) is a dynamic and multifaceted process that links the molecular alterations induced by or in response to prolonged ischemia with structural and physiological..

Perfusfind S.L.

Abstract Background Audiovisual recording technology, referred to as the Operating Room Black Box (ORBB), is increasingly adopted in operating rooms (ORs) across several countries. It is described as beneficial, with..

Perfusfind S.L.

Abstract Since the use of heparin reversed by protamine is the gold standard for anticoagulation during cardiopulmonary bypass (CPB), a documented allergy to protamine represents a serious challenge for cardiac..

Perfusfind S.L.

Abstract Background: Andexanet alfa, a Gla-domainless mutant factor Xa (GDXa), reverses oral FXa inhibitors but can cause severe heparin resistance during cardiopulmonary bypass (CPB). Antithrombin (AT) supplementation may mitigate this..

Perfusfind S.L.

Abstract SEVERE HEMOPTYSIS REMAINS A significant medical emergency, often requiring a multidisciplinary approach to identify the bleeding source and implement effective treatment. Airway obstruction due to clots secondary to massive..

Perfusfind S.L.

Abstract Background Extracorporeal membrane oxygenation (ECMO) has emerged as a crucial modality in managing severe cardiac and respiratory failure; however, nosocomial infections and complex antimicrobial prescribing challenges may accompany its..

Perfusfind S.L.

Abstract Background Protamine is administered to reverse unfractionated heparin (UFH) after cardiopulmonary bypass (CPB), but dosing strategies—typically based on protamine-to-heparin (P:H) ratios—vary, and the minimal effective dose remains unclear. Reversal..

Perfusfind S.L.

Abstract Despite significant advancements in critical care practice and extracorporeal technology, refractory hypoxia remains a persistent clinical challenge during extracorporeal membrane oxygenation (ECMO). To demonstrate a systematic, algorithmic pathway for..

Perfusfind S.L.

Abstract Objectives To evaluate the efficacy of intraoperative hemoadsorption (HA) during cardiopulmonary bypass (CPB) in reducing acute kidney injury (AKI) and other major postoperative complications in patients undergoing cardiac surgery...

Perfusfind S.L.

Abstract Background After chemotherapy, a small subset of mediastinal non-seminomatous germ cell tumors evolves into growing benign teratoma masses despite normalized tumor markers. This condition is termed the growing teratoma..

Perfusfind S.L.

Abstract Objective(s) To evaluate survival outcomes and identify candidate profiles for venoarterial extracorporeal membrane oxygenation in adult patients with sepsis-induced cardiomyopathy. Design The authors systematically searched PubMed, Embase, and Google..

Perfusfind S.L.

Abstract Background Drawing on more than 30 years of valuable expertise in in-vitro, in-vivo, and clinical trials, we report the key findings of our institutional research on pulsatile cardiopulmonary bypass..

Perfusfind S.L.

Abstract Previously, limited cumulative experience has been linked to poor transplantation outcomes following ex vivo lung perfusion (EVLP). We sought to determine if EVLP performed at external perfusion centers (EPC) could mitigate..

Perfusfind S.L.

Abstract Background The COVID-19 pandemic has exacerbated the backlog of elective surgeries across the National Health Service (NHS). This is particularly critical for patients awaiting cardiac surgery, where even short delays..

Perfusfind S.L.

Abstract Background While the use of pre-hospital extracorporeal cardiopulmonary resuscitation for refractory out of hospital cardiac arrest is increasing, there is little data on whether it is cost-effective. This study..

Perfusfind S.L.

Abstract Background: Veno-arterial ExtraCorporeal Membrane Oxygenation (V-A ECMO) as a bridge to recovery or long-term assist devices in severe cardiocirculatory failure typically lasts 5-7 days. There is scarce guidance on..

Perfusfind S.L.

Abstract Purpose Cardiopulmonary bypass (CPB) is a well-established procedure that uses cannulae during cardiac surgery to drain and return blood. In challenging cases (e.g. aortic dissection, reoperation), peripheral cannulation in..

Perfusfind S.L.

Abstract Background Heparin is commonly administered to prevent thrombosis during cardiopulmonary bypass (CPB). However, the development of intracardiac thrombi under CPB has still been reported. Case summary A 79-year-old man..

Perfusfind S.L.

Abstract Fast-track extubation has emerged as a vital component of Enhanced Recovery After Surgery pathways, designed to optimize recovery and resource utilization after cardiac surgery, contrasting with traditional prolonged ventilation...

Perfusfind S.L.

Abstract Objective Cardiopulmonary bypass (CPB), which induces pulmonary injury, significantly impacts the quality of life in patients undergoing cardiac surgery. Preventing and treating pulmonary complications has become a critical clinical..

Perfusfind S.L.

Abstract Malignant hyperthermia (MH) is a rare but potentially fatal disorder characterized by a hypermetabolic state produced by exposure to triggering agents such as volatile anesthetics and succinylcholine., MH crises have..

Perfusfind S.L.

Abstract Background Cardiac surgery with cardiopulmonary bypass (CPB) is associated with microcirculatory changes. Little is known about the effect of CPB on the structural and vascular parameters of the retina...

Perfusfind S.L.

Abstract INTRODUCTION Unfractionated heparin (UFH) is the most commonly used anticoagulant during extracorporeal membrane oxygenation (ECMO) (1). However, UFH also has several limitations: (i) it requires individualized dosing and close..

Perfusfind S.L.

Abstract Introduction Veno-venous extracorporeal membrane oxygenation (VV ECMO) is a life-sustaining technology that supports patients with severe acute respiratory failure. Indications and contraindications to VV ECMO are evolving and professional..

Perfusfind S.L.

Abstract Background Patients undergoing cardiac surgery frequently suffer impaired myocardial redox protection during cardiopulmonary bypass (CPB), with elderly patients facing higher complication risks. We investigated the redox-protective effects of blood..

Perfusfind S.L.

Abstract Background: Intraoperative iatrogenic aortic dissection (IAD) is an uncommon but serious complication of cardiac surgery, and available evidence remains limited, with most reports based on small series. This study..

Perfusfind S.L.

Abstract Background Acute kidney injury (AKI) is a common complication after pediatric cardiac surgery using cardiopulmonary bypass (CPB). This study evaluated renal regional oxygen saturation (R-rSO₂), measured via near-infrared spectroscopy..

Perfusfind S.L.

Abstract More than 1 million patients worldwide undergo cardiac surgery each year, amounting to approximately 123 per 100,000 population. Cardiopulmonary bypass has been central to this success, facilitating the possibility of..

Perfusfind S.L.

Abstract BACKGROUND:  Haptoglobin may reduce hemolysis-induced kidney injury in patients undergoing cardiovascular surgery with cardiopulmonary bypass (CPB). Haptoglobin may be given empirically when hemolytic urine is observed, or pre-emptively when..

Perfusfind S.L.

Abstract Objectives Del Nido cardioplegia has gained increasing popularity, evolving from its original use in paediatric and congenital heart surgery to widespread adoption in adult cardiac procedures. This review aims..