Venovenous extracorporeal membrane oxygenation (VVECMO) is a potent salvage therapy for ARDS patients who remain severely hypoxemic despite the use of more conventional treatments. In a study done in the UK, VVECMO improved the outcome of severe ARDS patients [1]. Critically ill patients require a high degree of acute care resources and nurses who have specialized knowledge and skills. Education and preparation beyond their basic nursing degree is therefore mandatory in order to provide an optimal level of care. In this short review, we describe ten important tips for nurses caring for patients receiving ECMO.