Tags Archives: ultrafiltration

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High-Exchange Ultrafiltration to Enhance Recovery After Pediatric Cardiac Surgery: The ULTRA Randomized Controlled Trial

Abstract Background Pediatric cardiac surgery with cardiopulmonary bypass (CPB) is associated with systemic inflammation. This trial aimed to determine whether continuous high-exchange ultrafiltration during CPB has a clinical immunomodulatory effect...

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Ultrafiltration in the critically ill patient: a framework for personalized care

Abstract Fluid overload is common after resuscitation in critically ill patients and is independently associated with unfavorable outcomes. Ultrafiltration (UF) during renal replacement therapy is a common strategy to reverse..

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Zero-Balance Ultrafiltration Reduces Postoperative Delirium After Cardiac Surgery with Cardiopulmonary Bypass: A Randomized Controlled Trial

Abstract Purpose To assess the effects of conventional ultrafiltration and conventional plus zero-balanced ultrafiltration on delirium and cognition in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods A total..

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Blood Prime Of The Cardiopulmonary Bypass Circuit In Congenital Heart Surgery

Abstract Introduction: The use of cardiopulmonary bypass (CPB) is necessary during the repair of most congenital heart disease (CHD). The surface area of the CPB circuit and the volume of..

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Preparation of a cardiopulmonary bypass priming solution for infants and neonates – effect of pre-bypass ultrafiltration on heparinization

Abstract Introduction Heparin is usually added to infant cardiopulmonary bypass circuit primes. Ultrafiltration is often used to minimise prime volume before commencing bypass. The extent of heparin removal from bypass..

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Pre-bypass ultrafiltration reduces cytokine burden of blood prime in pediatric cardiac surgery

Abstract Allogeneic red blood cells (RBCs) are commonly used for cardiopulmonary bypass (CPB) circuit priming in congenital heart surgery. While convection-based pre-bypass ultrafiltration (PBUF) corrects acid–base, electrolyte, and metabolite imbalances,..

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Ultrafiltration During Cardiopulmonary Bypass: Enhanced Review of Clinical Evidence and Application

1. Introduction Cardiopulmonary bypass (CPB) leads to pronounced hemodilution and provokes a systemic inflammatory response from blood interaction with artificial surfaces (Ziyaeifard et al., 2014) (, ). Ultrafiltration (UF) mitigates these effects..

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Postoperative hemoglobin changes following ultrafiltration in cardiac patients

Abstract Introduction This retrospective study investigated the relationship between differing thresholds of Conventional Ultrafiltration (CUF) and postoperative hemoglobin (HGB) in cardiac surgery cases involving cardiopulmonary bypass. Methods The study utilized..

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Ultrafiltration During Cardiac Surgery Requiring Cardiopulmonary Bypass and Its Effect on Acute Kidney Injury

Abstract Objective To explore whether ultrafiltration (UF) volume adjusted for weight is associated with an increased risk of acute kidney injury (AKI) after cardiopulmonary bypass (CPB) in cardiac surgery patients...

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High-exchange ULTrafiltration to enhance recovery after paediatric cardiac surgery (ULTRA): study protocol for a Canadian double-blinded randomised controlled trial

Abstract Introduction Surgical repair is the standard of care for most infants and children with congenital heart disease. Cardiopulmonary bypass (CPB) is required to facilitate these operations but elicits a systemic..

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Is ultrafiltration volume a predictor of postoperative acute kidney injury in patients undergoing cardiopulmonary bypass?

Abstract Introduction: Intraoperative ultrafiltration (UF) is a procedure used during cardiopulmonary bypass (CPB) to reduce haemodilution and prevent excessive blood transfusion. However, the effect of UF volume on acute kidney injury..

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Development of new colloid osmotic pressure measurement method using ultrafiltration membrane during cardiopulmonary bypass

Abstract Background: Clinical practice of measuring colloid osmotic pressure (COP) was abandoned after correcting hypoosmolarity did not improve overall patient outcomes. However, the use of albumin and colloidal solutions has..

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Impact of pre-bypass ultrafiltration on prime values and clinical outcomes in neonatal and infant cardiopulmonary bypass

Abstract Background: A standard blood prime for cardiopulmonary bypass (CPB) in congenital cardiac surgery may possess non-physiologic values for electrolytes, glucose, and lactate. Pre-bypass Ultrafiltration (PBUF) can make these values..

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Continuous Ultrafiltration Enhances Recovery After Adult Cardiac Surgery With Cardiopulmonary Bypass: A Systematic Review and Meta-analysis

Abstract Background Cardiac surgery with cardiopulmonary bypass is associated with systemic inflammation. Ultrafiltration used throughout the cardiopulmonary bypass time, continuously, is hypothesized to be an immunomodulatory therapy. Methods A systematic..

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Ultrafiltration in cardiac surgery: Results of a systematic review and meta-analysis

Abstract Background:   Ultrafiltration is used with cardiopulmonary bypass to reduce the effects of hemodilution and restore electrolyte balance. We performed a systematic review and meta-analysis to analyze the effect..

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Clinical Predictive Tool for Pediatric Cardiac Patients on Extracorporeal Membrane Oxygenation Therapy and Ultrafiltration

Abstract Fluid overload is common among pediatric cardiac patients receiving extracorporeal membrane oxygenation (ECMO) and is often treated with in-line ultrafiltration (UF) or continuous renal replacement therapy (CRRT). We assessed whether..

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Ultrafiltration and cardiopulmonary bypass associated acute kidney injury: A systematic review and meta-analysis

Abstract Background Cardiopulmonary bypass is known to raise the risk of acute kidney injury (AKI). Previous studies have identified numerous risk factors of cardiopulmonary bypass including the possible impact of..

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Subzero balance - simple modified ultrafiltration (SBUF-SMUF) technique for pediatric cardiopulmonary bypass

Abstract The use of cardiopulmonary bypass (CPB) can be associated with significant hemodilution, coagulopathy and a systemic inflammatory response for infants and children undergoing cardiac surgery. Intra-operative ultrafiltration has been..

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Retrograde Autologous Pump Prime (RAPP) vs UltraFiltration (UF)

Interesting a lively debate on Retrograde Autologous Pump Prime (RAPP) versus Ultrafiltration (UF) for volume control during cardiopulmonary bypass procedures.  

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RAPP Versus Ultrafiltration. Optimizing HGB. Alarm Desensitization.

Lectures and discussions about RAPP, On-Pump Ultrafiltration, Transfusion Management, and Alarm Desensitization.  

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Controversies in Perfusion. When to transfuse (Blood Transfusions)

Controversies in perfusion and cardiac surgery are common place. This program explores the controversial topic of transfusion and lowest acceptable hematocrit on pump. The panel also discusses ultrafiltration, flow rates..

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Impact of miniaturized cardiopulmonary bypass circuits on ultrafiltration during congenital heart surgery

Abstract   Objective: To investigate whether the miniaturized cardiopulmonary bypass (CPB) system decreased the usage of ultrafiltration (UF), and to explore whether the non-UF with miniaturized CPB strategy could get..

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The influence of ultrafiltration on red blood cell transfusion during cardiopulmonary bypass

Abstract Background: Ultrafiltration during cardiopulmonary bypass (CPB) reduces fluid overload and inflammatory mediators in open-heart surgery and is thought to reduce the risk of red blood cell (RBC) transfusion. We..

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Zero‐Balance Ultrafiltration of Priming Blood Attenuates Procalcitonin and Improves the Respiratory Function in Infants After Cardiopulmonary Bypass: A Randomized Controlled…

Abstract Blood priming is needed for cardiopulmonary bypass (CPB) in neonates and infants to avoid exceeding hemodilution; however, transfusion‐related inflammation affects post‐CPB outcomes in infant open‐heart surgery. Procalcitonin, a newly..

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Conventional Ultrafiltration During Elective Cardiac Surgery and Postoperative Acute Kidney Injury

Abstract Objective Conventional ultrafiltration (CUF) during cardiopulmonary bypass (CPB) serves to hemoconcentrate blood volume to avoid allogeneic blood transfusions. Previous studies have determined CUF volumes as a continuous variable are..

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