Tags Archives: anesthesia

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Volatile Anesthesia in Contemporary Cardiac Surgery: Clinical Implications, Organ Protection and Perspectives for Personalized Perioperative Care

Abstract Background: Interest in inhalational anesthesia in cardiac surgery has resurged as volatile anesthetics exert biological effects extending beyond hypnosis. Sevoflurane and desflurane activate mitochondrial cytoprotective signaling pathways, modulate inflammatory..

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Integration of Anesthesia and Perfusion Variables into Europe’s Largest Congenital Cardiac Surgery Outcomes Database: Methods and First List of Candidate…

Abstract Objectives Numerous databases exist in the field of cardiac surgery across Europe, but none of them combine the entire captured data of all clinical specialties involved in the care..

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Anesthetic Perspective on Total Arch Replacement With Frozen Elephant Trunk Surgery

Abstract The total arch replacement with frozen elephant trunk (TARFET) technique has emerged as a leading treatment for extensive aortic pathologies that span from the aortic arch to the proximal..

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Total Intravenous Versus Volatile Anesthesia in Pediatric Cardiac Surgery: Inflammatory Response and Early Recovery Profiles

Abstract Objectives To compare the effects of total intravenous anesthesia (TIVA) versus volatile anesthesia on systemic inflammation and early postoperative cognitive recovery in pediatric patients undergoing cardiac surgery with cardiopulmonary..

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Innovations in Risk Assessment, Monitoring, and Management in Cardiothoracic and Vascular Anesthesia

Abstract As the perioperative care in cardiothoracic and vascular anesthesia continues to evolve, more emphasis is being placed on developing innovative methods for risk assessment and early detection of operative..

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The role of extracorporeal membrane oxygenation in thoracic anesthesia

Abstract Purpose of review Circulatory and respiratory support with extracorporeal membrane oxygenation (ECMO) has gained widespread acceptance during high-end thoracic surgery. The purpose of this review is to summarize the..

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A novel, cassette-based nitric oxide delivery system with an advanced feedback control algorithm accurately delivers nitric oxide via the anesthesia…

Abstract Nitric oxide (NO), a selective pulmonary vasodilator, can be delivered via conventional ICU and anesthesia machine ventilators. Anesthesia machines are designed for rebreathing of circulating gases, reducing volatile anesthetic..

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The evolving role of the modern perfusionist: Insights from processed electro-encephalography

Abstract Introduction: Since its origin in the 1920s, electroencephalography (EEG) has become a viable option for anesthesia and perfusion teams to monitor anesthetic delivery, optimizing drug dosage and enhancing patient safety...

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Comparison of Propofol-Based Total Intravenous Anesthesia versus Volatile Anesthesia with Sevoflurane for Postoperative Delirium in Adult Coronary Artery Bypass Grafting…

Abstract Objectives To compare the incidence of delirium and early (at 1 week)  (POCD) between propofol-based  (TIVA) and volatile anesthesia with  in adult patients undergoing elective  (CABG) with  (CPB). Design This was a prospective randomized..

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Cardiopulmonary bypass for anesthetic management anterior medistinal teratoma: Case report

Abstract Introduction and importance Perioperative anesthetic management in cases of severe airway obstruction with positional symptoms can be associated with difficulties in ventilation or intubation, with a risk of acute..

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Complications of Cardiopulmonary Bypass From an Anesthesia Perspective: A Clinical Review

Abstract Cardiopulmonary bypass (CPB) is frequently used for open heart surgery and other procedures that utilize temporary substitution or support of heart and lung function. While it is widely accepted..

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Five commercial ‘depth of anaesthesia’ monitors provide discordant clinical recommendations in response to identical emergence-like EEG signals

Abstract Background ‘Depth of anaesthesia’ monitors claim to measure hypnotic depth during general anaesthesia from the EEG, and clinicians could reasonably expect agreement between monitors if presented with the same..

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Age-dependent electroencephalogram (EEG) patterns during sevoflurane general anesthesia in infants

Abstract Electroencephalogram (EEG) approaches may provide important information about developmental changes in brain-state dynamics during general anesthesia. We used multi-electrode EEG, analyzed with multitaper spectral methods and video recording of..

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Effect of Intraoperative Handovers of Anesthesia Care on Mortality, Readmission, or Postoperative Complications Among Adults

Abstract Importance  Intraoperative handovers of anesthesia care are common. Handovers might improve care by reducing physician fatigue, but there is also an inherent risk of losing critical information. Large observational analyses..

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Safety Culture in the Operating Room: Variability Among Perioperative Healthcare Workers

Abstract Introduction  Safety culture is defined as the product of individual and group values, attitudes, perceptions, competencies, and patterns of behavior that determine an organization’s health and safety management. There..

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The Case for the Anesthesiologist-Informaticist

Abstract Health care has been transformed by computerization, and the use of electronic health record systems has become widespread. Anesthesia information management systems are commonly used in the operating room..

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A Theoretical Model of Flow Disruptions for the Anesthesia Team During Cardiovascular Surgery

Abstract Objectives  This investigation explores flow disruptions observed during cardiothoracic surgery and how they serve to disconnect anesthesia providers from their primary task. We can improve our understanding of this..

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A Pharmacokinetic and Plasmin-Generation Pharmacodynamic Assessment of a Tranexamic Acid Regimen Designed for Cardiac Surgery With Cardiopulmonary Bypass

Abstract Objectives To examine the  (PK) and  of a tranexamic (TXA) regimen designed for cardiac surgery with  (CPB). Design A pilot study quantifying TXA concentrations,  markers, and a plasmin- generation (PG) assay. For comparison,..

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Rationale and design of the intravenous iron for treatment of anemia before cardiac surgery trial

Abstract Background Approximately 20% to 30% of patients awaiting cardiac surgery are anemic. Anemia increases the likelihood of requiring a red cell transfusion and is associated with increased complications, intensive care,..

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Anesthetic Management of Patients on ECMO

Abstract The management of a patient placed on extracorporeal membrane oxygenation (ECMO) is a team effort. The anesthesiology team plays an integral part during cannulation and oftentimes as well during..

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Intraoperative transfusion practices in Europe

Abstract Background.  Transfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to..

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An innovative technique to improve safety of volatile anesthetics suction from the cardiopulmonary bypass circuit

Abstract Context:  Myocardial injury during cardiac surgery on cardiopulmonary bypass (CPB) is a major determinant of morbidity and mortality. Preclinical and clinical evidence of dose- and time-related cardioprotective effects of..

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Vasopressinase Activity: A Potential Early Biomarker for Detecting Cardiopulmonary Bypass-Associated Acute Kidney Injury?

Abstract Background Acute kidney injury (AKI) is a common and serious complication of surgeries that include cardiopulmonary bypass (CPB). Currently, increases in serum creatinine levels are used to diagnose AKI,..

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Feasibility of autologous intraoperative blood collection and retransfusion in small children with complex congenital heart defects undergoing cardiopulmonary bypass

Abstract Introduction Allogeneic blood product transfusion is common in pediatric patients undergoing cardiopulmonary bypass although it is associated with an increased risk for adverse events. Furthermore, numerous donor exposures may..

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