Tags Archives: anemia

thumbnail
0 comment

Twenty-eight cases of thalassemia: A retrospective study of autologous and allogeneic erythrocyte transfusions during cesarean section

Abstract Aim Erythrocytes from patients with thalassemia might be susceptible to hemolysis during recycling and washing. Therefore, autologous erythrocyte transfusion using erythrocytes from parturient women with thalassemia has been suggested..

Read More
thumbnail
0 comment

Hemoglobin Optimization and Transfusion Reduction Through Anemia and Iron Deficiency Correction: A Post Hoc Prospective Study in Cardiac Surgery

Abstract Objectives To assess whether systematic perioperative correction of anemia and/or iron deficiency (ID) improves hemoglobin (Hb) levels and reduces transfusion requirements in elective cardiac surgery. Design Post hoc analysis..

Read More
thumbnail
0 comment

Anaemia and blood transfusion in cardiac surgery with infective endocarditis

Abstract Background Up to half of patients with infective endocarditis (IE) require cardiac surgery. Although anaemia is common, its precise prevalence, transfusion practices and impact on outcomes in surgically treated IE..

Read More
thumbnail
0 comment

Liberal or Restrictive Postoperative Transfusion in Patients at High Cardiac Risk

Abstract Importance  Postoperative red blood cell transfusion guidelines recommend transfusion for hemoglobin levels less than 7 g/dL. However, the safety of this strategy in patients at high risk of cardiac events..

Read More
thumbnail
0 comment

Early Postoperative Intravenous Iron Versus Oral Iron for the Treatment of Anemia Following Cardiac Surgery: A Randomized Controlled Trial

Abstract BACKGROUND:  Postoperative anemia is a common complication after cardiac surgery, often persisting for months and substantially affecting patient recovery. Despite its prevalence, optimal treatment strategies are lacking. We aimed..

Read More
thumbnail
0 comment

Analysis of Anemia, Transfusions, and CABG Outcomes in The Society of Thoracic Surgeons National Database

Abstract Background This study characterized the association of preoperative anemia and intraoperative red blood cell (RBC) transfusion on outcomes of elective coronary artery bypass grafting (CABG). Methods Data from 53,856..

Read More
thumbnail
0 comment

Alternative blood transfusion triggers: a narrative review

Abstract Background Anemia, characterized by low hemoglobin levels, is a global public health concern. Anemia is an independent factor worsening outcomes in various patient groups. Blood transfusion has been the..

Read More
thumbnail
0 comment

Preoperative Anemia and Postoperative Outcomes in Cardiac Surgery: A Mediation Analysis Evaluating Intraoperative Transfusion Exposures

Abstract BACKGROUND:  Preoperative anemia is associated with adverse outcomes in cardiac surgery, yet it remains unclear what proportion of this association is mediated through red blood cell (RBC) transfusions. METHODS: ..

Read More
thumbnail
0 comment

How low can you go: Restrictive transfusion strategies in major surgery and physiological triggers

Abstract Anemia and red blood cell transfusion are associated with adverse outcomes. Large randomized trials have demonstrated that restrictive transfusion strategies can safely reduce patient exposure to transfusion, forming a..

Read More
thumbnail
0 comment

Postoperative anemia in cardiac surgery patients: a narrative review

Abstract Purpose Anemia reduces the blood’s ability to carry and deliver oxygen. Following cardiac surgery, anemia is very common and affects up to 90% of patients. Nevertheless, there is a..

Read More
thumbnail
0 comment

Preoperative anemia and anemia treatment in cardiac surgery: a systematic review and meta-analysis

Abstract Purpose: We aimed to conduct a systematic review and meta-analysis to assess the effects of anemia and anemia severity on patient outcomes in cardiac surgery and determine whether preoperative treatments..

Read More
thumbnail
0 comment

Red Blood Cell Transfusion Requirements Before and After Implementation of a Perioperative Patient Blood Management Program in Adult Patients Undergoing…

Abstract Objectives Anemia and transfusion are common in cardiac surgery patients, and are associated with significant morbidity and mortality. Multiple perioperative interventions have been described to reduce blood transfusion, but..

Read More
thumbnail
0 comment

Methemoglobin as a marker of acute anemic stress in cardiac surgery

Abstract Biological evidence supports plasma methemoglobin as a biomarker for anemia-induced tissue hypoxia. In this translational planned substudy of the multinational randomized controlled transfusion thresholds in cardiac surgery (TRICS-III) trial,..

Read More
thumbnail
0 comment

Perioperative Trajectory of Haemoglobin, Predictors of Blood Transfusion and Tailoring Targets for Patient Blood Management Interventions: A Single-centre, Retrospective Study…

Abstract Background Anaemia and blood transfusion are two independent contributing factors to perioperative morbidity in cardiac surgery. While preoperative treatment of anaemia has been shown to improve outcomes, in real..

Read More
thumbnail
0 comment

Severe Acute Blood Loss Anemia in Jehovah's Witnesses Undergoing Cardiac Surgery: Single Academic Center Experience

Abstract Objective To determine the effect of severe acute blood loss anemia (ABLA) on postoperative outcomes in Jehovah's Witness (JW) patients undergoing cardiac surgery. Design This was a  of adult JW..

Read More
thumbnail
0 comment

The pressure field as a methodology for fluid management and red cell preservation during cardiac surgery

Abstract Purpose Anemia and red cell transfusion contribute to morbidity and mortality of surgery. The concept of patient blood management to mitigate preoperative anemia, optimize coagulation, conserve red cells intraoperatively..

Read More
thumbnail
0 comment

Cell Salvage at the ICU

Abstract Patient Blood Management (PBM) is a patient-centered, systemic and evidence-based approach. Its target is to manage and to preserve the patient’s own blood. The aim of PBM is to..

Read More
thumbnail
0 comment

Interaction of hemoglobin, transfusion, and acute kidney injury in patients undergoing cardiopulmonary bypass: a group-based trajectory analysis

Abstract Anemia is a risk factor for acute kidney injury (AKI) following cardiopulmonary bypass (CPB). Whether red blood cell (RBC) transfusion-enhanced hemoglobin levels contribute to low AKI rates remains unclear...

Read More
thumbnail
0 comment

Perioperative Quality Initiative and Enhanced Recovery After Surgery-Cardiac Society Consensus Statement on the Management of Preoperative Anemia and Iron Deficiency…

Abstract Preoperative anemia is common in patients presenting for cardiac surgery, with a prevalence of approximately 1 in 4, and has been associated with worse outcomes including increased risk of..

Read More
thumbnail
0 comment

Critical Preoperative Hemoglobin Value to Predict Anemia-Related Complications After Cardiac Surgery

Abstract Objectives Preoperative anemia is frequent in patients undergoing cardiac surgery and is associated with increased postoperative complications.  Design A retrospective observational cohort study. Setting A tertiary-care medical center from..

Read More
thumbnail
0 comment

Challenges in Patient Blood Management for Cardiac Surgery: A Narrative Review

Abstract About 15 years ago, Patient Blood Management (PBM) emerged as a new paradigm in perioperative medicine and rapidly found support of all major medical societies and government bodies. Blood..

Read More
thumbnail
0 comment

Effect of Perioperative Intravenous Iron Supplementation for Complex Cardiac Surgery on Transfusion Requirements

Abstract Objectives:  We investigated whether routine perioperative intravenous iron replenishment reduces the requirement for packed erythrocytes (pRBC) transfusion. Summary of Background Data:  Patients undergoing complex cardiac surgery are at high risk..

Read More
thumbnail
0 comment

Management of Perioperative Iron Deficiency in Cardiac Surgery: A Modified RAND Delphi Study

Abstract Background Over the last decade, preoperative anemia has become recognized as a clinical condition in need of management. Although the etiology of preoperative anemia can be multifactorial, two thirds..

Read More
thumbnail
0 comment

Preoperative Anemia and Risk for Perioperative Neurocognitive Dysfunction in Cardiac Surgery Patients: A Retrospective Analysis

Abstract Objectives To evaluate whether there is a relationship between preoperative anemia and domain-specific cognitive performance in patients undergoing cardiac surgery. Design Retrospective analysis of data collected from a randomized..

Read More
thumbnail
0 comment

Preoperative Anemia and Outcomes After Corrective Surgery in Neonates With Dextro-Transposition of the Great Arteries

Abstract Objectives The authors aimed to assess whether untreated preoperative anemia was associated with increased risk for adverse outcomes after the arterial switch operation in neonates with dextro-transposition of the..

Read More
thumbnail
0 comment

Towards manufactured red blood cells for the treatment of inherited anemia

Abstract Patients with inherited anemia and hemoglobinopathies (such as sickle cell disease and β-thalassemia) are treated with red blood cell (RBC) transfusions to alleviate their symptoms. Some of these patients..

Read More
thumbnail
0 comment

Controversies in the Clinical Practice of Patient Blood Management

Abstract Patient blood management (PBM) has been proposed as a standard of care in modern . PBM-related interventions usually are implemented as bundles, but randomized controlled trials on the implementation of..

Read More
thumbnail
0 comment

Rationale and design of the intravenous iron for treatment of anemia before cardiac surgery trial

Abstract Background Approximately 20% to 30% of patients awaiting cardiac surgery are anemic. Anemia increases the likelihood of requiring a red cell transfusion and is associated with increased complications, intensive care,..

Read More
thumbnail
0 comment

Randomized Pilot Trial of Acute Normovolemic Hemodilution in Pediatric Cardiac Surgery Patients

Abstract Background: Due to the substantial improvement in survival among pediatric patients undergoing congenital heart surgery, reducing early and long-term morbidity is becoming the major focus of care. Blood transfusion is..

Read More
thumbnail
0 comment

Blood transfusion trends by disease category in the United States, 2000 to 2014

Abstract Background Better understanding of blood usage rates could identify trends in transfusion practices over time and inform more efficient management. Methods Inpatient admissions from the Healthcare Cost and Utilization..

Read More