Tags Archives: Acute kidney injury (AKI)

thumbnail
0 comment

Risk factors, outcomes, and early prediction of cardiac surgery-associated acute kidney injury: a post hoc subgroup analysis of the Epidemiology…

Abstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and important complication. The risk factors for CSA-AKI remain poorly described. We aimed to identify risk factors for CSA-AKI..

Read More
thumbnail
0 comment

Biomarkers of multi-organ dysfunction in ECMO: prognostic signposts for palliative transitions

Abstract Consistently high lactate levels and poor clearance on ECMO are important early signs of poor perfusion and useless care. For example, lactate levels over 8 mmol/L at 12 h, staying above..

Read More
thumbnail
0 comment

Predictive Power of the Association of Cardiothoracic Anesthetists Perioperative Risk of Blood Transfusion Score for Cardiac Surgery–Associated Acute Kidney Injury:…

Abstract Objectives The Association of Cardiothoracic Anesthetists Perioperative Risk of Blood Transfusion (ACTA-PORT) score was originally developed to predict the need for transfusion in cardiac surgery patients. Given the inter-relationship..

Read More
thumbnail
0 comment

From Coronary Contrast to Renal Injury: The Emerging Role of Endothelial Dysfunction

Abstract Introduction Contrast-induced acute kidney injury (CIAKI) is a common and serious complication of coronary angiography, caused by iodinated contrast agents. It significantly worsens cardiovascular prognosis and increases in-hospital morbidity..

Read More
thumbnail
0 comment

Intraoperative Hemoadsorption and Acute Kidney Injury in Cardiac Surgery: Systematic Review and Meta-analysis

Abstract Cardiovascular surgery with cardiopulmonary bypass (CPB) is associated with several potential complications, including the activation of inflammatory and coagulation pathways, which may lead to acute kidney injury (AKI). In..

Read More
thumbnail
0 comment

Early Predictors of Acute Kidney Injury After Pediatric Cardiopulmonary Bypass: A Retrospective Cohort Analysis

Abstract Background:  Acute kidney injury (AKI) is a frequent complication of congenital heart surgery with cardiopulmonary bypass (CPB) in pediatric patients, contributing to significant morbidity and mortality. Aim:  To determine..

Read More
thumbnail
0 comment

Predicting In-Hospital Acute Kidney Injury after Cardiac Surgery Using Machine Learning

Abstract Objective We aimed to develop and evaluate cardiac surgery–associated acute kidney injury (CSA-AKI) machine learning prediction models that included clinical variables, biomarkers, and high-frequency hemodynamic measurements. Design A prospective,..

Read More
thumbnail
0 comment

Improving urinary oxygen monitoring with a transit time algorithm: enhancing AKI detection in cardiac surgery

Abstract Acute kidney injury (AKI) affects 40–50% of cardiac surgery patients and is closely linked to renal medullary hypoxia. Although urinary oxygen partial pressure (PuO2) offers real-time insight into renal..

Read More
thumbnail
0 comment

Explainable machine learning models for early prediction of acute kidney injury after cardiac surgery

Abstract Background This study aimed to develop a data-driven prediction model for cardiac surgery-associated acute kidney injury (CSA-AKI) at the end of surgery using machine learning (ML) algorithms. Methods We..

Read More
thumbnail
0 comment

Acute Kidney Injury in Cardiac Surgery: A Comprehensive Review of Perioperative Strategies and Emerging Biomarkers

Abstract Acute kidney injury (AKI) is a significant complication following cardiac surgery, affecting 20% to 30% of patients and contributing to increased morbidity and mortality. Cardiac surgery–associated AKI (CSA-AKI) is..

Read More
thumbnail
0 comment

Iron-related protein in prediction of acute kidney injury in the pediatric population after cardiac surgery

Abstract Background Acute Kidney Injury (AKI) is a frequent post-operative complication following cardiac surgery in the clinical setting. Iron metabolism disorders are a key cause of kidney injury during the..

Read More
thumbnail
0 comment

Perioperative Acute Kidney Injury: What’s New in 2025?

Abstract Perioperative acute kidney injury (AKI) is a frequent complication that affects outcomes well beyond the perioperative period. Its mechanisms remain incompletely understood, arising from the interplay of comorbidities, surgical..

Read More
thumbnail
0 comment

Continuous furosemide does not prevent cardiopulmonary bypass-related acute kidney injury in minimally invasive cardiac surgery: the randomized furosemide trial

Abstract Objectives: This study aimed to assess whether continuous furosemide administration during cardiopulmonary bypass (CPB) in minimally invasive cardiac surgery (MICS) reduces the incidence of cardiac surgery-associated acute kidney injury..

Read More
thumbnail
0 comment

Development and validation of a prediction model for acute kidney injury following cardiopulmonary bypass surgery

Abstract Background Acute renal impairment following cardiopulmonary bypass (CPB) is a serious perioperative complication with sustained occurrence. Proactive risk assessment and preventive strategies are crucial for enhancing surgical outcomes. Methods..

Read More
thumbnail
0 comment

Performance of Supervised Machine Learning Models for Cardiac Surgery-Associated Acute Kidney Injury in Children: Multicenter Retrospective Cohort Study, 2019–2022

Abstract Objectives:  To derive and externally validate supervised machine learning (ML) models predictive of cardiac surgery-associated acute kidney injury (CS-AKI). Design:  Retrospective cohort analysis. Setting:  Multicenter (4), cardiac surgical centers..

Read More
thumbnail
0 comment

Tissue Oxygen Saturation Combined With Serum Lactic Acid Can Predict Cardiac Surgery–Associated Acute Kidney Injury

Abstract Objectives To investigate the potential contribution of tissue oxygenation prediction in cardiac surgery–associated acute kidney injury (CSA-AKI) using near-infrared spectroscopy (NIRS) and serum lactate level measurements. Design A retrospective..

Read More
thumbnail
0 comment

Single-cell immune landscape of acute kidney injury after cardiac surgery with cardiopulmonary bypass

Abstract Objectives Acute kidney injury (AKI) occurs in 19–42% of patients with cardiac surgery under cardiopulmonary bypass (CPB). Clarifying their landscape of immune cells may help discover the mechanisms and..

Read More
thumbnail
0 comment

Acute Kidney Injury After Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest

Abstract OBJECTIVES:  Acute kidney injury (AKI) occurs frequently in ICUs and is associated with poor outcomes. However, little is known about AKI in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR) for..

Read More
thumbnail
0 comment

Kidney & extracorporeal support interactions: a narrative review

Abstract Purpose of review  Acute kidney injury (AKI) is common in critically ill patients, especially among those with severe and advanced organ failure. The use of extracorporeal support (ECS) is..

Read More
thumbnail
0 comment

Dextran vs. Crystalloid Priming Solution in Cardiac Surgery: A Randomized Trial on Acute Kidney Injury

Abstract Background Acute kidney injury (AKI) is a frequent complication following cardiac surgery involving cardiopulmonary bypass (CPB). This is partly attributable to crystalloid-based priming solutions causing both hemolysis and loss..

Read More
thumbnail
0 comment

Patient-Specific Susceptibility to the Nadir Oxygen Delivery on Cardiopulmonary Bypass

Abstract Objectives Maintaining a nadir oxygen delivery ≥ 280 mL/min/m2 during cardiopulmonary bypass is a pillar of the goal-directed perfusion strategy in cardiac surgery. However, there are patients who develop a..

Read More
thumbnail
0 comment

Prognostic value of venous-to-arterial pCO2 gap during cardiopulmonary bypass for predicting cardiac surgery-associated kidney injury: A bicentric retrospective study

Abstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is one of the most frequent and severe complications after cardiac surgery. The association between acute kidney injury and the mismatch between..

Read More
thumbnail
0 comment

Development, Validation, and Testing of a Simple Risk Score System Incorporating Routine Clinical and Laboratory Variables to Predict Moderate-to-Severe Acute…

Abstract Objectives Early prediction is crucial for cardiac surgery-associated acute kidney injury (CSA-AKI). We aimed to develop and validate a simple, clinical- and laboratory-based risk score system for better CSA-AKI..

Read More
thumbnail
0 comment

Intraoperative Dexmedetomidine Enhances Postoperative Microcirculation and Reduces Acute Kidney Injury in Cardiac Surgery: A Double-Blind Randomized Trial

Abstract Purpose: Dexmedetomidine, an alpha-2 adrenergic agonist, has shown potential benefits in various surgical settings, but its impact on microcirculation and renal function in cardiac surgery patients remains unclear. Patients and..

Read More
thumbnail
0 comment

Monitoring Oxygen Delivery During Cardiopulmonary Bypass: A Preliminary Multinational Practice Survey

Abstract Objectives Oxygen delivery (DO2) is a pivotal factor in maintaining adequate tissue protection during cardiopulmonary bypass (CPB). Despite its clinical significance, there is currently no global consensus regarding standardized..

Read More
thumbnail
0 comment

Decreased renal or cerebral oxygen saturation increases the risk of cardiac surgery-associated acute kidney injury in adult patients: a prospective…

Abstract Objective To determine the relationship between intraoperative decreased renal and cerebral oxygen saturation, as measured using near-infrared spectroscopy (NIRS), and cardiac surgery-associated acute kidney injury (CSA-AKI) in adults. Methods..

Read More
thumbnail
0 comment

Mean arterial pressure difference before and during cardiopulmonary bypass: what should be the ideal mean perfusion pressure?

Abstract Objectives: The difference between mean arterial pressure (MAP) before cardiopulmonary bypass (CPB) and mean perfusion pressure (MPP) during CPB is thought to be a strong predictor of acute kidney injury..

Read More
thumbnail
0 comment

Hemolysis Index and Cardiopulmonary Bypass Time as Predictors of Cardiac Surgery-associated Acute Kidney Injury: An Observational Cohort Study

Abstract Objectives Acute kidney injury (AKI) is a common and serious complication of cardiac surgery, often linked to the use and duration of cardiopulmonary bypass (CPB). The Hemolysis Index (HI)..

Read More
thumbnail
0 comment

Cell-free hemoglobin is associated with microcirculatory perfusion disturbances and acute kidney injury in rats on extracorporeal membrane oxygenation

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life-saving treatment, but carries a high risk of complications such as acute kidney injury (AKI). A contributor to AKI is hemolysis, which..

Read More
thumbnail
0 comment

Assessment of Renal Vein Flow Index by Transesophageal Echocardiography: Precision, Variability, and Association with Cardiac Index During Cardiac Surgery

Abstract Objectives Cardiac surgery-associated acute kidney injury (CSA-AKI) is a frequent and important complication often attributed to decreased kidney blood flow. Ultrasound measurement of renal  has been associated with adverse cardiac..

Read More