Pediatric

Perfusfind S.L.

Abstract Purpose Achieving effective anticoagulation during neonatal extracorporeal membrane oxygenation (ECMO) without increasing the risk of hemorrhage remains challenging. The use of antithrombin III (AT-III) for this purpose has been examined, but studies have been limited to intermittent bolus dosing. We aimed to evaluate the efficacy and safety of an..

Perfusfind S.L.

Abstract Objectives:  To describe the use of extracorporeal membrane oxygenation (ECMO) in the management of pediatric poisoning in the United States and to identify predictors of mortality. Design:  Retrospective cohort study. Setting:  Data reported to the Extracorporeal Life Support Organization by 76 U.S. ECMO centers from 2003 to 2019. Patients:  Pediatric patients..

Perfusfind S.L.

Abstract Background Delirium is acute brain dysfunction associated with serious illness. Emerging data indicate that delirium occurs in greater than 20% of children in pediatric intensive care units. Cardiac bypass surgery is a known risk factor for delirium in adults, but has never been systematically studied in pediatrics. Objectives To..

Perfusfind S.L.

Abstract This retrospective cohort study describes all children transported on extracorporeal life support (ECLS) by the Stollery Children’s Hospital Pediatric Transport team (SCH-PTT) between 2004 and 2018. We compared outcomes and complications between primary (SCH-PTT performed ECLS cannulation) vs. secondary (cannulation performed by referring facility) transports, as well as secondary transports from referring centers..

Perfusfind S.L.

Abstract È l’Ospedale Pediatrico Bambino Gesù, in collaborazione con 5 società scientifiche internazionali, a mettere per la prima volta a disposizione di rianimatori e oncoematologi le Linee Guida per il trattamento con ossigenazione extracorporea (ECMO) dei pazienti pediatrici sottoposti al . Il documento, strutturato in 36 raccomandazioni, pone anche l’attenzione sugli aspetti etici dell’uso dell’ECMO..

Perfusfind S.L.

Abstract Use of extracorporeal membrane oxygenation (ECMO) in children receiving haematopoietic cell transplantation (HCT) and immune effector cell therapy is controversial and evidence-based guidelines have not been established. Remarkable advancements in HCT and immune effector cell therapies have changed expectations around reversibility of organ dysfunction and survival for affected patients...

Perfusfind S.L.

Abstract OBJECTIVES:  To describe the association between left heart decompression on veno-arterial extracorporeal membrane oxygenation and survival in patients with myocarditis and dilated cardiomyopathy. The secondary outcome is to study association of left heart decompression with survival in children with myocarditis compared with those with dilated cardiomyopathy. DESIGN:  Retrospective study..

Perfusfind S.L.

Abstract Background Inflammatory and endothelial activation responses during extracorporeal membrane oxygenation (ECMO) support in children are poorly understood. In this study, we aimed to determine if circulating inflammatory, endothelial activation, and fibrinolytic markers are associated with mortality and with neurologic outcomes in children on ECMO. Methods We conducted a secondary..

Perfusfind S.L.

Abstract BACKGROUND  The relicensing of aprotinin in Europe and Canada has stimulated discussions on its usefulness in paediatric cardiac surgery. OBJECTIVE  To systematically evaluate the available evidence on the efficacy and safety of aprotinin in paediatric cardiac surgery. DESIGN  Systematic review of all randomised and observational studies comparing aprotinin with..

Perfusfind S.L.

Abstract Background Suboptimal tissue perfusion and oxygenation may be the root cause of certain perioperative complications in neonates and infants having complicated aortic coarctation repair. Practical, effective, and real-time monitoring of organ perfusion and/or tissue oxygenation may provide early warning of end-organ mal-perfusion. Methods Neonates/infants who were scheduled for aortic..