Pediatric

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Association of Arterial Hyperoxia With Outcomes in Critically Ill Children

Abstract Importance  Oxygen supplementation is a cornerstone treatment in pediatric critical care. Accumulating evidence suggests that overzealous use of oxygen, leading to hyperoxia, is associated with worse outcomes compared with patients with normoxia. Objectives  To evaluate the association of arterial hyperoxia with clinical outcome in critically ill children among studies using varied..

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Extracorporeal Membrane Oxygenation for Septic Shock in Children

Abstract Extracorporeal membrane oxygenation (ECMO) is a rescue treatment used in children and adults with reversible cardiorespiratory failure. The role of ECMO is not fully established in pediatric sepsis. In this retrospective single-center study, we aimed to investigate risk factors and survival in pediatric septic shock supported with peripheral cannulation ECMO. All..

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ELSO Guidelines for Adult and Pediatric Extracorporeal Membrane Oxygenation Circuits

Abstract This guideline describes the ECMO circuit for all patient populations. These guidelines describe safe practice based on extensive experience and are considered consensus guidelines. These guidelines are not intended to define standard of care and are revised at regular intervals as new information, devices, medications, and techniques become available.

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Tracheostomy Practices and Outcomes in Children During Respiratory Extracorporeal Membrane…

Abstract Objectives:  Children receiving prolonged extracorporeal membrane oxygenation (ECMO) support may benefit from tracheostomy during ECMO by facilitating rehabilitation; however, the procedure carries risks, especially hemorrhagic complications. Knowledge of tracheostomy practices and outcomes of ECMO-supported children who undergo tracheostomy on ECMO may inform decision-making. Design:  Retrospective cohort study. Setting:  ECMO centers contributing to the Extracorporeal Life..

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2021 ELSO Adult and Pediatric Anticoagulation Guidelines

Abstract Anticoagulation is necessary for most pediatric and adult extracorporeal membrane oxygenation (ECMO) patients to prevent circuit clotting. Inherently, the most common side effect of anticoagulation is bleeding. Anticoagulation during ECMO is complex due to patient critical illness, interactions between the patient and ECMO circuit, and the inflammatory responses of..

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Somatic Support with Veno-venous ECMO in a Pregnant Woman with…

Abstract Supporting homeostasis in a pregnant woman with brain death to achieve fetal viability is called somatic support. We present a case of young pregnant woman at 21 weeks’ gestation who developed acute respiratory distress syndrome secondary to influenza A H2N3 infection requiring veno-venous extracorporeal membrane oxygenation (VV ECMO) support..

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Vacuum-assisted venous drainage, angel or demon: PRO?

Abstract Vacuum-assisted venous drainage (VAVD) was proposed to optimize venous drainage during bypass through femoral venous cannulation. It is currently used in both adult and pediatric surgery when siphon gravity venous drainage is suboptimal. In pediatric surgery, the major advantages of VAVD are a significant decrease in cardiopulmonary bypass prime..

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Antithrombin III infusion improves anticoagulation in congenital diaphragmatic hernia patients…

Abstract Purpose Achieving effective anticoagulation during neonatal extracorporeal membrane oxygenation (ECMO) without increasing the risk of hemorrhage remains challenging. The use of antithrombin III (AT-III) for this purpose has been examined, but studies have been limited to intermittent bolus dosing. We aimed to evaluate the efficacy and safety of an..

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Use of Extracorporeal Membrane Oxygenation in Acutely Poisoned Pediatric Patients…

Abstract Objectives:  To describe the use of extracorporeal membrane oxygenation (ECMO) in the management of pediatric poisoning in the United States and to identify predictors of mortality. Design:  Retrospective cohort study. Setting:  Data reported to the Extracorporeal Life Support Organization by 76 U.S. ECMO centers from 2003 to 2019. Patients:  Pediatric patients..

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