Pediatric

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Early Implantation of Extracorporeal Membrane Oxygenator After Open-Heart Surgery

Abstract Extracorporeal membrane oxygenator (ECMO) is effective for maintaining oxygenation and hemodynamic support in patients with post-cardiotomy cardiogenic shock (PCCS). Researchers, led by Ahmed Abdeljawad, sought to compare the effect of early ECMO implantation in emergency patients versus elective patients who developed univentricular or biventricular pump failure. After their trial,..

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Extracorporeal membrane oxygenation in children with COVID-19 and PIMS-TS during…

Abstract During the first wave of the COVID-19 pandemic, the European Extracorporeal Life Support Organization (ELSO) established a prospective survey including 52 European neonatal and paediatric centres and reported the use of extracorporeal membrane oxygenation (ECMO) in seven children with acute respiratory distress syndrome (ARDS) related to COVID-19 and paediatric..

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The myocardial protective effects of adenosine pretreatment in children undergoing…

Abstract Objective: Adenosine pretreatment reduces injury caused by ischemia-reperfusion. To investigate the hypothesis that adenosine pretreatment would modulate injury induced by cardiopulmonary bypass (CPB) and myocardial ischemia/reperfusion, we conducted a randomized controlled trial on the effects of adenosine pretreatment in children undergoing surgery to repair congenital heart defects. Methods: Children undergoing surgery..

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The association between end-tidal carbon dioxide and arterial partial pressure…

Abstract Introduction: Evidence suggests the high capability of non-invasive assessment of the End-tidal carbondioxide (ETCO2) in predicting changes in arterial carbon dioxide pressure (PCO2) following major surgeries in children. We aimed to compare EtCO2 values measured by capnography with mainstream device and EtCO2 values assessed by arterial blood gas analysis before..

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A systematic review of the evidence supporting post-operative antithrombotic use…

Abstract Objectives:To determine the optimal antithrombotic agent choice, timing of initiation, dosing and duration of therapy for paediatric patients undergoing cardiac surgery with cardiopulmonary bypass. Methods:We used PubMed and EMBASE to systematically review the existing literature of clinical trials involving antithrombotics following cardiac surgery from 2000 to 2020 in children..

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Evaluating the Impact of Cardiopulmonary Bypass Priming Fluids on Bleeding…

Abstract Objectives Cardiopulmonary bypass (CPB) predisposes young children to coagulopathy. The authors evaluated possible effects of CPB priming fluids on perioperative bleeding in pediatric cardiac surgery. Design Meta-analysis and systematic review of previously published studies. Setting Each study was conducted in a surgical center or intensive care unit. Participants Studies..

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Extracorporeal Life Support Organization Guideline for Transport and Retrieval of…

Abstract Disclaimer:  This extracorporeal life support organization guideline describes the preparation for and undertaking of transport and retrieval of patients on extracorporeal membrane oxygenation (ECMO). The guideline describes useful and safe practice put together by an international multidisciplinary team with extensive experience in the field of ECMO and ECMO transport...

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The Fundamental Skills and Deconstructed Sub-Steps of Pediatric Cardiopulmonary Bypass

Abstract Perfusion education programs use simulation to provide students with clinical skills prior to entering the operating room. To teach the psychomotor execution of skills in a simulation lab requires a list of validated skills and deconstructed sub-steps to fully optimize adult learning. A list of the fundamental skills of..

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Effect of CPB Glucose Levels on Inflammatory Response After Pediatric…

Abstract Background: Systemic inflammatory response syndrome (SIRS) is a common complication after cardiac surgery. There are no definite optimal glycemic threshold for pediatric patients receiving open-heart surgery with CPB. The study aimed to investigate the optimal cardiopulmonary bypass (CPB) glucose in patients undergoing cardiac surgery. Methods: We enrolled children with..

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Plasma and Platelet Transfusions Strategies in Neonates and Children Undergoing…

Abstract Objectives:  To present the recommendations and consensus statements with supporting literature for plasma and platelet transfusions in critically ill neonates and children undergoing cardiac surgery with cardiopulmonary bypass or supported by extracorporeal membrane oxygenation from the Transfusion and Anemia EXpertise Initiative–Control/Avoidance of Bleeding. Design:  Systematic review and consensus conference..

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