Pediatric

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Hemolysis during Pediatric Extracorporeal Membrane Oxygenation: Associations with Circuitry, Complications,…

Abstract Objective: To describe factors associated with hemolysis during pediatric extracorporeal membrane oxygenation (ECMO), and the relationships between hemolysis, complications and mortality. Design: Secondary analysis of data collected prospectively by the Collaborative Pediatric Critical Care Research Network (CPCCRN) between December 2012 and September 2014. Setting: Three CPCCRN-affiliated hospitals. Patients: Age..

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Transfusion policy in pediatric extracorporeal membrane oxygenation patients: Less could…

Abstract Objective To evaluate a restrictive transfusion policy of red blood cells (RBC) and platelets in pediatric patients submitted to extracorporeal membrane oxygenation (ECMO). Methods Retrospective descriptive study of pediatric patients supported with ECMO, from January 2010 to December 2019. Hemoglobin, platelet, lactate and mixed venous oxygen saturation (SvO2) values..

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Bivalirudin vs. heparin in paediatric and adult patients on extracorporeal…

Abstract Aims Unfractionated heparin (UFH) has been the primary anticoagulant of choice on extracorporeal membrane oxygenation (ECMO). However, it is debatable whether bivalirudin (BIV), a direct thrombin inhibitor, may be considered a better alternative anticoagulant option. Methods We searched Embase, Pubmed, Cochrane library, , CNKI and Wanfang databases up to 15..

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Inferior and Superior Vena Cava Saturation Monitoring After Neonatal Cardiac…

Abstract OBJECTIVES:  Superior vena cava oxygen saturation (SVC O2) monitoring is well described for early detection of hemodynamic deterioration after neonatal cardiac surgery but inferior vena cava vein oxygen saturation (IVC O2) monitoring data are limited. DESIGN:  Retrospective cohort study of 118 neonates with congenital heart disease (52 single ventricle) from February 2008 to..

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Optimal Sweep Gas to Blood Flow Ratio (V/Q) for Initiation…

Abstract The optimal setting to achieve a suitable PaCO2 value of 35–45 mmHg upon initiating cardiopulmonary bypass (CPB) in the pediatric population is undefined in the literature. Sweep gas is set upon initiating and modified throughout CPB to reduce potential complications related to compensatory metabolic acidosis or metabolic alkalosis and associated..

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Extracorporeal Membrane Oxygenation Outcomes in Children With Preexisting Neurologic Disorders…

Abstract OBJECTIVE:  Patient selection for pediatric extracorporeal membrane oxygenation (ECMO) support has broadened over the years to include children with pre-existing neurologic morbidities. We aimed to determine the prevalence and nature of pre-ECMO neurologic disorders or disability and investigate the association between pre-ECMO neurologic disorders or disability and mortality and..

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Del Nido cardioplegia: from an infant conceive to an adult…

Abstract The increasing number of minimally invasive procedures prompted the quest for a simple and effective single shot cardioplegia to allow the surgeons to focus on their workflow. The originally pediatric Del Nido solution was successfully tested in several centers and gradually extended to regular coronary and valvular cases. In..

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Recent advancements in pediatric cardiopulmonary bypass technology for better outcomes…

Abstract Background Pediatric cardiac surgery is in itself very enigmatic and individualized. Presently, there has been a slew of new developments aimed primarily toward pediatric cardiopulmonary bypass for safer, patient-centered pediatric cardiac surgery. Still, lot of technological challenges need to be resolved, and their safer application in pediatric and neonate..

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Hemoadsorption for severe MIS-C in critically ill children, should we…

This case reports on a 13 year old boy (weight 60 kg, height 160 cm) who presented with fever, rash, abdominal pain, and vomiting. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/08/CoW_32_2022_E_web_compressed.pdf"]

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Thrombosis in Extracorporeal Membrane Oxygenation (ECMO) Circuits

Abstract Thrombosis in extracorporeal membrane oxygenation (ECMO) circuits remains a frequent complication. We characterize the location, extent, structure, and clinical implications of thrombi in 53 ECMO circuits from 46 pediatric patients. The tubing, pump, and oxygenator were examined for visible thrombi. Representative samples of thrombi were collected for histologic, immunofluorescence, and..

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