Pediatric

Perfusfind S.L.

Abstract Objective Several human studies have associated nitric oxide administration via the cardiopulmonary bypass circuit with decreased incidence of cardiopulmonary bypass–associated acute kidney injury, but histopathologic and serologic evidence of nitric oxide efficacy for acute kidney injury attenuation are lacking. Methods By using a survival ovine model (72 hours), acute kidney..

Perfusfind S.L.

Abstract Pediatric Literature As the practice of ultrafiltration arose from pediatric cardiac surgery, much of the evidence to support MUF is from low-powered pediatric studies. Some early, single-center literature, as published by Schlünzen et al., observed that MUF, when compared with CUF, increased systolic blood pressure, hematocrit, arterial oxygen, and..

Perfusfind S.L.

Abstract Hemodilution and Volume Overload The use of CPB necessitates priming of the CPB circuit, which is typically accomplished using 1-to-2 liters of a crystalloid solution. In addition, 1-to-3 liters of cardioplegia (CP) are primed within a separate arm of the CPB circuit, all of which eventually make their way..

Perfusfind S.L.

The patient is a two-and-a-half-year-old child with d-TGA/VSD/PS who underwent aortic translocation. The patient’s anatomy was typical of d-transposition with VSD and PS. Both coronaries were favorable in that they were off of the epicardium. The information and views presented on CTSNet.org represent the views of the authors and contributors..

Perfusfind S.L.

Abstract Clinicians caring for children with cardiopulmonary failure using extracorporeal membrane oxygenation (ECMO) are refining bedside clinical practices by focusing on minimizing morbidity associated with neurologic complications. Neurologic complications are the main drivers of survival and survivorship (). Both enhanced neuromonitoring (,) and neuroimaging () serve to characterize neurologic morbidity to help the field establish..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) augments cardiopulmonary function in critically ill children through use of large vessel cannulation and an external pump-oxygenator system. While advances in ECMO have allowed more children to survive otherwise fatal illnesses, the incidence of significant neurologic injury, such as cerebral ischemia, hemorrhage, or brain death has..

Perfusfind S.L.

Abstract The advantages and disadvantages of using corticosteroids in children undergoing cardiac surgery is still contentious. To examine how perioperative corticosteroids affect postoperative mortality and clinical outcomes in pediatric cardiac surgery with cardiopulmonary bypass (CPB). We used MEDLINE, EMBASE, and the Cochrane Database to conduct a comprehensive search up through..

Perfusfind S.L.

Abstract Children with cardiac disease are at a higher risk of cardiac arrest as compared to healthy children. Delivering adequate cardiopulmonary resuscitation (CPR) can be challenging due to anatomic characteristics, risk profiles, and physiologies. We aimed to review the physiological aspects of resuscitation in different cardiac physiologies, summarize the current..

Perfusfind S.L.

Abstract Background  Fluid overload is a serious complication in the treatment of infants with extracorporeal membrane oxygenation (ECMO). Volume overload leads to prolonged ECMO therapy if left untreated. The renal replacement therapy of choice in pediatric patients is peritoneal dialysis or conventional dialysis using a “large” hemofiltration machine via a..

Perfusfind S.L.

Abstract Longitudinal assessment of brain perfusion is a critical parameter for neurodevelopmental outcome of neonates undergoing cardiopulmonary bypass procedure. In this study, we aim to measure the variations of cerebral blood volume (CBV) in human neonates during cardiac surgery, using Ultrafast Power Doppler and freehand scanning. To be clinically relevant,..